Cellular FLICE-Inhibitory Protein Regulates Tissue Homeostasis

Author(s):  
Hiroyasu Nakano ◽  
Xuehua Piao ◽  
Ryodai Shindo ◽  
Sachiko Komazawa-Sakon

Planta Medica ◽  
2014 ◽  
Vol 80 (10) ◽  
Author(s):  
J Oh ◽  
H Li ◽  
WM Elshamy ◽  
MT Hamann


Author(s):  
Natale D'Alessandro ◽  
Lydia Giannitrapani ◽  
Manuela Labbozzetta ◽  
Paola Poma ◽  
Luigi Inguglia ◽  
...  


2020 ◽  
Vol 10 (5) ◽  
pp. 861-877
Author(s):  
Ziqiao Yuan ◽  
Zihang Yuan ◽  
Muhammad Hasnat ◽  
Haoran Zhang ◽  
Peishi Liang ◽  
...  


Biomolecules ◽  
2021 ◽  
Vol 11 (2) ◽  
pp. 336
Author(s):  
Roberta Melchionna ◽  
Paola Trono ◽  
Annalisa Tocci ◽  
Paola Nisticò

Human tissues, to maintain their architecture and function, respond to injuries by activating intricate biochemical and physical mechanisms that regulates intercellular communication crucial in maintaining tissue homeostasis. Coordination of the communication occurs through the activity of different actin cytoskeletal regulators, physically connected to extracellular matrix through integrins, generating a platform of biochemical and biomechanical signaling that is deregulated in cancer. Among the major pathways, a controller of cellular functions is the cytokine transforming growth factor β (TGFβ), which remains a complex and central signaling network still to be interpreted and explained in cancer progression. Here, we discuss the link between actin dynamics and TGFβ signaling with the aim of exploring their aberrant interaction in cancer.



2021 ◽  
Vol 1862 (7) ◽  
pp. 148429
Author(s):  
Romero-Aguilar Lucero ◽  
Esparza-Perusquía Mercedes ◽  
Langner Thorsten ◽  
García-Cruz Giovanni ◽  
Feldbrügge Michael ◽  
...  


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