scholarly journals Severe Respiratory Acidosis in Status Epilepticus as a Possible Etiology of Sudden Death in Lesch–Nyhan Disease: A Case Report and Review of the Literature

2016 ◽  
pp. 23-28 ◽  
Author(s):  
Alison Christy ◽  
William Nyhan ◽  
Jenny Wilson
Author(s):  
Gabriela Tantillo ◽  
Navyamani Kagita ◽  
Maite LaVega-Talbott ◽  
Anuradha Singh ◽  
David Kaufman

AbstractNorovirus is a common cause of acute gastroenteritis outbreaks worldwide. The disease can present with varying degrees of neurologic impairment from benign convulsions to rare cases of severe encephalopathy. We describe a case report of a North American infant who presented with norovirus gastroenteritis, status epilepticus, severe encephalopathy, and abnormal but reversible diffusion restriction changes on magnetic resonance imaging of brain.


Injury ◽  
2005 ◽  
Vol 36 (1) ◽  
pp. 213-217 ◽  
Author(s):  
Theodore Vougiouklakis ◽  
Dimitrios Peschos ◽  
Apostolos Doulis ◽  
Anna Batistatou ◽  
Antigone Mitselou ◽  
...  

2015 ◽  
Vol 19 (6) ◽  
pp. 730-732 ◽  
Author(s):  
Orkun Tolunay ◽  
Tamer Çelik ◽  
Mustafa Kömür ◽  
Ali Emre Gezgin ◽  
Musa Soner Kaya ◽  
...  

Author(s):  
Alberto M. Cappellari ◽  
Donata Rossetti ◽  
Sabrina Avignone ◽  
Elisa Scola ◽  
Antonio Di Cesare

AbstractMetronidazole-induced encephalopathy is a rare toxic encephalopathy secondary to the common use to this antimicrobial drug. It has been reported mainly in adult patients but only rarely in children. Owing to possible devastating complication of this disease, clinicians should have a higher index of suspicion for encephalopathic patients on metronidazole therapy. Here, we report a 5-month-old infant with metronidazole-induced encephalopathy presenting with nonconvulsive status epilepticus. A review of the literature in pediatric, as well as adult metronidazole-induced encephalopathy, is also provided.


2017 ◽  
Vol 5 ◽  
pp. 2050313X1774520 ◽  
Author(s):  
Marc-Alain Babi ◽  
Christopher P Robinson ◽  
Carolina B Maciel

Synthetic cannabinoids refer to a wide variety of chemicals engineered to bind cannabinoid receptors (CB1 and CB2) and mimic the effects of delta-9-tetrahydrocanabinol. The potential for severe toxicity and limited in vivo data make synthetic cannabinoid intake an important public health and safety concern. Neurologic toxidromes associated with their use include mental status changes, panic attacks, memory distortions, acute psychosis (e.g. paranoia, delusional thoughts), disorganized behavior, and suicidal and homicidal thoughts. Systemic complications include vomiting, sinus tachycardia, myocardial infarction, and acute kidney injury. Seizures are common; however, status epilepticus is not widely reported. In this case report, we describe a patient who developed acute psychosis and new-onset refractory status epilepticus necessitating emergent neurological life-support and prolonged admission to an intensive care unit following abuse of synthetic cannabinoids. We include a brief review of the literature to prepare the treating clinician for the broad clinical spectrum of this increasingly common intoxication.


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