Cancer Growth: A Nonclassical Nonlinear Phenomenon?

2006 ◽  
pp. 119-129
Author(s):  
C. A. Condat ◽  
B. F. Gregor ◽  
Y. Mansury ◽  
T. S. Deisboeck
Keyword(s):  
Cancer Growth ◽  
Nonlinear Phenomenon

Extracellular matrix: the gatekeeper of tumor angiogenesis

2019 ◽  
Vol 47 (5) ◽  
pp. 1543-1555 ◽  
Author(s):  
Maurizio Mongiat ◽  
Simone Buraschi ◽  
Eva Andreuzzi ◽  
Thomas Neill ◽  
Renato V. Iozzo
Keyword(s):  
Extracellular Matrix ◽  
Tumor Angiogenesis ◽  
Signaling Cascades ◽  
Cancer Growth ◽  
Cell Behavior ◽  
Metastatic Progression ◽  
Surface Receptors ◽  
The Matrix ◽  
Multiple Signaling

Abstract The extracellular matrix is a network of secreted macromolecules that provides a harmonious meshwork for the growth and homeostatic development of organisms. It conveys multiple signaling cascades affecting specific surface receptors that impact cell behavior. During cancer growth, this bioactive meshwork is remodeled and enriched in newly formed blood vessels, which provide nutrients and oxygen to the growing tumor cells. Remodeling of the tumor microenvironment leads to the formation of bioactive fragments that may have a distinct function from their parent molecules, and the balance among these factors directly influence cell viability and metastatic progression. Indeed, the matrix acts as a gatekeeper by regulating the access of cancer cells to nutrients. Here, we will critically evaluate the role of selected matrix constituents in regulating tumor angiogenesis and provide up-to-date information concerning their primary mechanisms of action.

Passive smoking may speed cancer growth

Nature ◽  
2003 ◽  
Author(s):  
HelenR. Pilcher
Keyword(s):  
Passive Smoking ◽  
Cancer Growth

Is GH a cancer growth factor?

2017 ◽  
Author(s):  
Shlomo Melmed
Keyword(s):  
Growth Factor ◽  
Cancer Growth

Combined Treatment with Exendin-4 and Metformin Attenuates Breast Cancer Growth

Diabetes ◽  
2018 ◽  
Vol 67 (Supplement 1) ◽  
pp. 1227-P
Author(s):  
CHIKAYO IWAYA ◽  
TAKASHI NOMIYAMA ◽  
TAKAKO KAWANAMI ◽  
YURIKO HAMAGUCHI ◽  
TOMOKO TANAKA ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Combined Treatment ◽  
Cancer Growth ◽  
Breast Cancer Growth

1955-P: GLP-1R Activation Attenuates Prostate Cancer Growth via Inhibiting Cell Cycle Progression

Diabetes ◽  
2019 ◽  
Vol 68 (Supplement 1) ◽  
pp. 1955-P
Author(s):  
TORU SHIGEOKA ◽  
TAKASHI NOMIYAMA ◽  
TAKAKO KAWANAMI ◽  
YURIKO HAMAGUCHI ◽  
TOMOKO TANAKA ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Cell Cycle ◽  
Cell Cycle Progression ◽  
Cancer Growth ◽  
Cycle Progression
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