Introduction to the Different Classes of Biosynthetic Enzymes

2009 ◽  
pp. 143-163 ◽  
Author(s):  
Luzia V. Modolo ◽  
Angelika I. Reichert ◽  
Richard A. Dixon
Keyword(s):  
Biosynthetic Enzymes

scholarly journals A roadmap for metagenomic enzyme discovery

2021 ◽  
Author(s):  
Serina L. Robinson ◽  
Jörn Piel ◽  
Shinichi Sunagawa
Keyword(s):  
Biosynthetic Enzymes ◽  
Functional Metagenomics ◽  
Enzyme Discovery ◽  
Experimental Strategies

Shotgun metagenomic approaches to uncover new enzymes are underdeveloped relative to PCR- or activity-based functional metagenomics. Here we review computational and experimental strategies to discover biosynthetic enzymes from metagenomes.

scholarly journals Ancient origin of fucosylated xyloglucan in charophycean green algae

2021 ◽  
Vol 4 (1) ◽  
Author(s):  
Maria Dalgaard Mikkelsen ◽  
Jesper Harholt ◽  
Bjørge Westereng ◽  
David Domozych ◽  
Stephen C. Fry ◽  
...  
Keyword(s):  
Green Algae ◽  
Structural Component ◽  
Cell Walls ◽  
Uronic Acid ◽  
Structural Elucidation ◽  
Land Plants ◽  
Evolutionary Significance ◽  
Biosynthetic Enzymes ◽  
Major Structural Component ◽  
Mesotaenium Caldariorum

AbstractThe charophycean green algae (CGA or basal streptophytes) are of particular evolutionary significance because their ancestors gave rise to land plants. One outstanding feature of these algae is that their cell walls exhibit remarkable similarities to those of land plants. Xyloglucan (XyG) is a major structural component of the cell walls of most land plants and was originally thought to be absent in CGA. This study presents evidence that XyG evolved in the CGA. This is based on a) the identification of orthologs of the genetic machinery to produce XyG, b) the identification of XyG in a range of CGA and, c) the structural elucidation of XyG, including uronic acid-containing XyG, in selected CGA. Most notably, XyG fucosylation, a feature considered as a late evolutionary elaboration of the basic XyG structure and orthologs to the corresponding biosynthetic enzymes are shown to be present in Mesotaenium caldariorum.

Gene expression of catecholamine biosynthetic enzymes following exercise: modulation by age

Neuroscience ◽  
2001 ◽  
Vol 103 (3) ◽  
pp. 703-711 ◽  
Author(s):  
N. Tümer ◽  
H.A. Demirel ◽  
L. Serova ◽  
E.L. Sabban ◽  
C.S. Broxson ◽  
...  
Keyword(s):  
Gene Expression ◽  
Biosynthetic Enzymes

scholarly journals Spontaneous Amplification of the Actinorhodin Gene Cluster in Streptomyces coelicolor Involving Native Insertion Sequence IS466

2008 ◽  
Vol 190 (13) ◽  
pp. 4754-4758 ◽  
Author(s):  
E. M. Widenbrant ◽  
Hsiu-Hui Tsai ◽  
Carton W. Chen ◽  
C. M. Kao
Keyword(s):  
Transposable Element ◽  
Gene Cluster ◽  
Insertion Sequence ◽  
Streptomyces Coelicolor ◽  
Biosynthetic Enzymes ◽  
Genes Encoding ◽  
Amplification Mechanism

ABSTRACT We observed a spontaneous amplification of the Streptomyces coelicolor chromosome, including genes encoding biosynthetic enzymes of the antibiotic actinorhodin. A new junction of two tandem segments has, inserted within it, a third copy of a transposable element existing in two places elsewhere in the chromosome, suggesting its involvement in the amplification mechanism.

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