Quantifying variation in human dental development sequences: An EVO-DEVO perspective

2007 ◽  
pp. 247-261 ◽  
Author(s):  
J. Braga ◽  
Y. Heuze
Keyword(s):  
Dental Development ◽  
Evo Devo

Dental Development in Children After Chemotherapy

2017 ◽  
Vol 68 (6) ◽  
pp. 1397-1400
Author(s):  
Cristina Bica ◽  
Mihaela Chincesan ◽  
Daniela Esian ◽  
Krisztina Martha ◽  
Valentin Ion ◽  
...  
Keyword(s):  
Acute Lymphoblastic Leukemia ◽  
Tooth Development ◽  
Lymphoblastic Leukemia ◽  
Treatment Method ◽  
Paediatric Oncology ◽  
Structural Defects ◽  
Dental Development ◽  
Cytostatic Agents ◽  
Dental Abnormalities ◽  
Tooth Buds

Chemotherapy, as a treatment method in paediatric oncology, coincides with the physiological process of tooth development. The interference between cytostatic agents and the cycle of the cells with specialised functions in the formation and mineralisation of dental structures leads to the appearance of abnormalities in the development of the tooth buds, structural defects and disorderly eruption. We have looked into the distribution of developmental tooth disorders in a group of children suffering from malignant ailments. The study reveals a high occurrence of microdontia and agenesis of premolars among children diagnosed with high-risk acute lymphoblastic leukemia at the age between 1 and 6, as well as tooth eruption disturbances in 70% of the children. The nature and the severity of dental abnormalities depend on the type of cytostatic medication, the dosage and the frequency of therapeutic cycles, the age of the child at the beginning of the oncological therapy, as well as on the stage of the odontogenesis.

Serial Homology as a Challenge to Evolutionary Theory

2017 ◽  
Author(s):  
Stéphane Schmitt
Keyword(s):  
Biological Sciences ◽  
Evolutionary Theory ◽  
Serial Homology ◽  
The Core ◽  
Long Period ◽  
Colonial Theory ◽  
Experimental Approaches ◽  
Evo Devo ◽  
The 19Th Century ◽  
Development And Evolution

The problem of the repeated parts of organisms was at the center of the biological sciences as early as the first decades of the 19th century. Some concepts and theories (e.g., serial homology, unity of plan, or colonial theory) introduced in order to explain the similarity as well as the differences between the repeated structures of an organism were reused throughout the 19th and the 20th century, in spite of the fundamental changes during this long period that saw the diffusion of the evolutionary theory, the rise of experimental approaches, and the emergence of new fields and disciplines. Interestingly, this conceptual heritage was at the core of any attempt to unify the problems of inheritance, development, and evolution, in particular in the last decades, with the rise of “evo-devo.” This chapter examines the conditions of this theoretical continuity and the challenges it brings out for the current evolutionary sciences.

Evo-Devo and the Structure(s) of Evolutionary Theory

2017 ◽  
Author(s):  
Alan C. Love
Keyword(s):  
Developmental Biology ◽  
Evolutionary Theory ◽  
Mechanistic Explanation ◽  
Evolutionary Developmental Biology ◽  
Primary Concern ◽  
Adaptive Function ◽  
Specific Content ◽  
Central Location ◽  
Developmental Form ◽  
Evo Devo

Many researchers have argued that evolutionary developmental biology (evo-devo) constitutes a challenge to standard evolutionary theory, requiring the explicit inclusion of developmental processes that generate variation and attention to organismal form (rather than adaptive function). An analysis of these developmental-form challenges indicates that the primary concern is not the inclusion of specific content but the epistemic organization or structure of evolutionary theory. Proponents of developmental-form challenges favor moving their considerations to a more central location in evolutionary theorizing, in part because of a commitment to the value of mechanistic explanation. This chapter argues there are multiple legitimate structures for evolutionary theory, instead of a single, overarching or canonical organization, and different theory presentations can be understood as idealizations that serve different investigative and explanatory goals in evolutionary inquiry.

Comment on “Evo‐Devo and the lungfish: the last gasp of intelligent design”

2007 ◽  
Vol 21 (11) ◽  
pp. 2640-2641 ◽  
Author(s):  
J. S. Torday ◽  
Virender K. Rehan
Keyword(s):  
Intelligent Design ◽  
Evo Devo

Deconstructing and reconstructing joint hypermobility on an evo-devo perspective

Rheumatology ◽  
2021 ◽  
Author(s):  
Marco Castori
Keyword(s):  
Evolutionary Biology ◽  
Phenotypic Variability ◽  
Morphological Variability ◽  
Complex Trait ◽  
Joint Hypermobility ◽  
Integration Model ◽  
Ehlers Danlos Syndrome ◽  
Evo Devo ◽  
Derivatives Of ◽  
Continuous Traits

Abstract Joint hypermobility is a common characteristic in humans. Its non-casual association with various musculoskeletal complaints is known and currently defined “the spectrum”. It includes hypermobile Ehlers–Danlos syndrome (hEDS) and hypermobility spectrum disorders (HSD). hEDS is recognized by a set of descriptive criteria, while HSD is the background diagnosis for individuals not fulfilling these criteria. Little is known about the aetiopathogenesis of the spectrum. It may be interpreted as a complex trait according to the integration model. Particularly, the spectrum is common in the general population, affects morphology, presents extreme clinical variability and is characterized by marked sex bias without a clear Mendelian or hormonal explanation. Joint hypermobility and the other hEDS systemic criteria are intended as qualitative derivatives of continuous traits of normal morphological variability. The need for a minimum set of criteria for hEDS diagnosis implies a tendency to co-vary of these underlying continuous traits. In evolutionary biology, such a co-variation (i.e. integration) is driven by multiple forces, including genetic, developmental, functional and environmental/acquired interactors. The aetiopathogenesis of the spectrum may be resolved by a deeper understanding of phenotypic variability, which superimposes on normal morphological variability.

scholarly journals Eco-evo-devo advances with butterfly eyespots

2021 ◽  
Vol 69 ◽  
pp. 6-13
Author(s):  
Patrícia Beldade ◽  
Antónia Monteiro
Keyword(s):  
Evo Devo

scholarly journals The importance of TNAP/Tnap for dental development in human cell culture and in zebrafish

Bone Reports ◽  
2021 ◽  
Vol 14 ◽  
pp. 101006
Author(s):  
Stephanie Graser ◽  
Sofia Paulus ◽  
Elisa Riekert ◽  
Franz Jakob ◽  
Eva Klopocki ◽  
...  
Keyword(s):  
Cell Culture ◽  
Human Cell ◽  
Dental Development ◽  
Human Cell Culture
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