Transport Systems for Arsenic, Antimony, and Cadmium Ions Encoded by Bacterial Plasmids

Author(s):  
Anita R. Lynn ◽  
Barry P. Rosen
1990 ◽  
Vol 22 (4) ◽  
pp. 493-507 ◽  
Author(s):  
Louis S. Tisa ◽  
Barry P. Rosen

Author(s):  
Andrew Thacker

This innovative book examines the development of modernism in four European cities: London, Paris, Berlin, and Vienna. Focusing upon how literary and cultural outsiders represented various spaces in these cities, it draws upon contemporary theories of affect, mood, and literary geography to offer an original account of the geographical emotions of modernism. It considers three broad features of urban modernism: the built environment of the particular cities, such as cafés or transport systems; the cultural institutions of publishing that underpinned the development of modernism in these locations; and the complex perceptions of writers and artists who were outsiders to the four cities. Particular attention is thus given to the transnational qualities of modernism by examining figures whose view of the cities considered is that of migrants, exiles, or strangers. The writers and artists discussed include Mulk Raj Anand, Gwendolyn Bennett, Bryher, Blaise Cendrars, Joseph Conrad, T. S. Eliot, Christopher Isherwood, Hope Mirlees, Noami Mitchison, Jean Rhys, Sam Selon, and Stephen Spender.


2020 ◽  
Vol 31 (1) ◽  
pp. 3-10
Author(s):  
V. S. Nedzvetsky ◽  
V. Ya. Gasso ◽  
A. M. Hahut ◽  
I. A. Hasso

Cadmium is a common transition metal that entails an extremely wide range of toxic effects in humans and animals. The cytotoxicity of cadmium ions and its compounds is due to various genotoxic effects, including both DNA damage and chromosomal aberrations. Some bone diseases, kidney and digestive system diseases are determined as pathologies that are closely associated with cadmium intoxication. In addition, cadmium is included in the list of carcinogens because of its ability to initiate the development of tumors of several forms of cancer under conditions of chronic or acute intoxication. Despite many studies of the effects of cadmium in animal models and cohorts of patients, in which cadmium effects has occurred, its molecular mechanisms of action are not fully understood. The genotoxic effects of cadmium and the induction of programmed cell death have attracted the attention of researchers in the last decade. In recent years, the results obtained for in vivo and in vitro experimental models have shown extremely high cytotoxicity of sublethal concentrations of cadmium and its compounds in various tissues. One of the most studied causes of cadmium cytotoxicity is the development of oxidative stress and associated oxidative damage to macromolecules of lipids, proteins and nucleic acids. Brain cells are most sensitive to oxidative damage and can be a critical target of cadmium cytotoxicity. Thus, oxidative damage caused by cadmium can initiate genotoxicity, programmed cell death and inhibit their viability in the human and animal brains. To test our hypothesis, cadmium cytotoxicity was assessed in vivo in U251 glioma cells through viability determinants and markers of oxidative stress and apoptosis. The result of the cell viability analysis showed the dose-dependent action of cadmium chloride in glioma cells, as well as the generation of oxidative stress (p <0.05). Calculated for 48 hours of exposure, the LD50 was 3.1 μg×ml-1. The rates of apoptotic death of glioma cells also progressively increased depending on the dose of cadmium ions. A high correlation between cadmium concentration and apoptotic response (p <0.01) was found for cells exposed to 3–4 μg×ml-1 cadmium chloride. Moreover, a significant correlation was found between oxidative stress (lipid peroxidation) and induction of apoptosis. The results indicate a strong relationship between the generation of oxidative damage by macromolecules and the initiation of programmed cell death in glial cells under conditions of low doses of cadmium chloride. The presented results show that cadmium ions can induce oxidative damage in brain cells and inhibit their viability through the induction of programmed death. Such effects of cadmium intoxication can be considered as a model of the impact of heavy metal pollution on vertebrates.


2016 ◽  
Vol 52 (4) ◽  
pp. 74-80
Author(s):  
Yu. I. Senyk ◽  
V. O. Khomenchuk ◽  
V. Z. Kurant ◽  
V. V. Grubinko
Keyword(s):  

2018 ◽  
Vol 4 (10) ◽  
pp. 10
Author(s):  
Ankur Mishra ◽  
Aayushi Priya

Transportation or transport sector is a legal source to take or carry things from one place to another. With the passage of time, transportation faces many issues like high accidents rate, traffic congestion, traffic & carbon emissions air pollution, etc. In some cases, transportation sector faced alleviating the brutality of crash related injuries in accident. Due to such complexity, researchers integrate virtual technologies with transportation which known as Intelligent Transport System. Intelligent Transport Systems (ITS) provide transport solutions by utilizing state-of-the-art information and telecommunications technologies. It is an integrated system of people, roads and vehicles, designed to significantly contribute to improve road safety, efficiency and comfort, as well as environmental conservation through realization of smoother traffic by relieving traffic congestion. This paper aims to elucidate various aspects of ITS - it's need, the various user applications, technologies utilized and concludes by emphasizing the case study of IBM ITS.


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