The Influence of Calcium on Mitochondrial Membrane Transport and Fluidity

1986 ◽  
pp. 425-426
Author(s):  
A. Cooke ◽  
D. Collison ◽  
F. E. Mabbs ◽  
M. J. Earnshaw
Keyword(s):  
Membrane Transport ◽  
Mitochondrial Membrane

SVCT2-Dependent plasma and mitochondrial membrane transport of ascorbic acid in differentiating myoblasts

2020 ◽  
Vol 159 ◽  
pp. 105042
Author(s):  
Mara Fiorani ◽  
Maddalena Scotti ◽  
Andrea Guidarelli ◽  
Sabrina Burattini ◽  
Elisabetta Falcieri ◽  
...  
Keyword(s):  
Ascorbic Acid ◽  
Membrane Transport ◽  
Mitochondrial Membrane

scholarly journals Shock-Induced Alterations of Mitochondrial Membrane Transport

1972 ◽  
Vol 176 (5) ◽  
pp. 579-584 ◽  
Author(s):  
GARY G. NICHOLAS ◽  
LEENA M. MELA ◽  
LEONARD D. MILLER
Keyword(s):  
Membrane Transport ◽  
Mitochondrial Membrane

Early alterations in mitochondrial membrane transport during endotoxemia

1974 ◽  
Vol 16 (4) ◽  
pp. 375-383 ◽  
Author(s):  
Gary G. Nicholas ◽  
Leena M. Mela ◽  
Leonard D. Miller
Keyword(s):  
Membrane Transport ◽  
Mitochondrial Membrane

Glucose metabolism in cancer cells: immunogold localization of hexokinase to the outer mitochondrial membrane

1995 ◽  
Vol 53 ◽  
pp. 1044-1045
Author(s):  
Krishan K. Arora ◽  
Glenn L. Decker ◽  
Peter L. Pedersen
Keyword(s):  
Tumor Cells ◽  
Mitochondrial Membrane ◽  
Present Report ◽  
Large Fraction ◽  
Mitochondrial Fraction ◽  
Immunogold Labeling ◽  
Outer Mitochondrial Membrane ◽  
Immunogold Localization ◽  
Hexokinase Activity ◽  
Normal Tissues

Hexokinase (ATP: D-hexose 6-phophotransferase EC 2.7.1.1) is the first enzyme of the glycolytic pathway which commits glucose to catabolism by catalyzing the phosphorylation of glucose with ATP. Previous studies have shown diat hexokinase activity is markedly elevated in rapidly growing tumor cells exhibiting high glucose catabolic rates. A large fraction (50-80%) of this enzyme activity is bound to the mitochondrial fraction (1,2) where it has preferred access to ATP (3). In contrast,the hexokinase activity of normal tissues is quite low, with one exception being brain which is a glucose-utilizing tissue (4). Biochemical evidence involving rigorous subfractionation studies have revealed striking differences between the subcellular distribution of hexokinase in normal and tumor cells [See review by Arora et al (4)].In the present report, we have utilized immunogold labeling techniques to evaluate die subcellular localization of hexokinase in highly glycolytic AS-30D hepatoma cells and in the tissue of its origin, i.e., rat liver.

Modulation of the calcium-activated BK-channel of the inner mitochondrial membrane by hypoxia

2007 ◽  
Vol 34 (S 2) ◽  
Author(s):  
D Siemen ◽  
Y Cheng ◽  
X Gu ◽  
P Bednarczyk ◽  
GG Haddad ◽  
...  
Keyword(s):  
Mitochondrial Membrane ◽  
Bk Channel ◽  
Inner Mitochondrial Membrane
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