Some Research Needs to Support Mutagenicity Risk Assessments from Whole Mammal Studies

Author(s):  
Ernest R. Jackson ◽  
John R. Fowle ◽  
Peter E. Voytek
2001 ◽  
Vol 36 (2) ◽  
pp. 303-317
Author(s):  
Roger Sutcliffe

Abstract The ecological risk assessment of commercial chemicals in Canada by the regulatory programs of the Commercial Chemicals Evaluation Branch, Environment Canada, are based on results from traditional toxicity data (e.g., lethality, effects to growth or reproduction). Some of the chemicals under consideration are known to alter endocrine systems in exposed organisms; however, effects to the endocrine system are used only as additional supporting information. Presently, there are no internationally accepted methodologies or tests for endocrine disrupting substances that can be used by these regulatory programs. The need for research with respect to hormone disrupting substances has been recognized in the revised Canadian Environmental Protection Act, 1999 (CEPA 1999). This paper describes the framework for the ecological risk assessment of new and existing substances and identifies issues and research needs in both screening level and in-depth ecological risk assessments with respect to the identification and assessment of potentially endocrine disrupting substances.


2015 ◽  
Vol 25 (1) ◽  
pp. 15-23 ◽  
Author(s):  
Ryan W. McCreery ◽  
Elizabeth A. Walker ◽  
Meredith Spratford

The effectiveness of amplification for infants and children can be mediated by how much the child uses the device. Existing research suggests that establishing hearing aid use can be challenging. A wide range of factors can influence hearing aid use in children, including the child's age, degree of hearing loss, and socioeconomic status. Audiological interventions, including using validated prescriptive approaches and verification, performing on-going training and orientation, and communicating with caregivers about hearing aid use can also increase hearing aid use by infants and children. Case examples are used to highlight the factors that influence hearing aid use. Potential management strategies and future research needs are also discussed.


Polymer News ◽  
2004 ◽  
Vol 29 (7) ◽  
pp. 220-223
Author(s):  
Charles Carraher, Jr.
Keyword(s):  

Polymer News ◽  
2004 ◽  
Vol 29 (2) ◽  
pp. 58-60
Author(s):  
Charles Carraher, Jr.
Keyword(s):  

2013 ◽  
Vol 3 (1) ◽  
pp. 9-18 ◽  
Author(s):  
Catherine Joseph ◽  
Suhasini Reddy ◽  
Kanwal Kashore Sharma

Locus of control (LOC), safety attitudes, and involvement in hazardous events were studied in 205 Indian Army aviators using a questionnaire-based method. A positive correlation was found between external LOC and involvement in hazardous events. Higher impulsivity and anxiety, and decreased self-confidence, safety orientation, and denial were associated with a greater number of hazardous events. Higher external LOC was associated with higher impulsivity, anxiety, and weather anxiety and with lower self-confidence, safety orientation, and denial. Internal LOC was associated with increased self-confidence, safety orientation, and denial. Hazardous events and self-confidence were higher in those involved in accidents than those not involved in accidents. Future research needs to address whether training can effectively modify LOC and negative attitudes, and whether this would cause a reduction in, and better management of, human errors.


2013 ◽  
Vol 25 (2) ◽  
pp. 95-104 ◽  
Author(s):  
Coy Callison ◽  
Rhonda Gibson ◽  
Dolf Zillmann

This study used an experimental news report about confrontational robberies by adolescent groups in Mexican resorts that presented statistics with or without personalized cases of victimization. Study participants estimated the risk of harm to victims and the extent of their suffering. They also indicated their own risk and concern for their own safety. The readers’ numeric ability was ascertained thereafter. A trisection of this ability showed that persons of high ability comparatively overestimated others’ risk but underestimated their own; this despite indicating greater concerns for their own safety. These results were not altered by consideration of the readers’ empathic, experiential, and rational traits. The incorporation of personalized cases of victimization in the news report did not appreciably influence risk assessments. The involvement of cases resulting in major bodily injury, however, increased estimates of the incidence of such robberies.


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