Physiological Role of Reactive Oxygen Species in Sperm Function: A Review

2013 ◽  
pp. 69-89 ◽  
Author(s):  
Aaron Thompson ◽  
Ashok Agarwal ◽  
Stefan S. du Plessis
Keyword(s):  
Reactive Oxygen Species ◽  
Physiological Role ◽  
Reactive Oxygen ◽  
Sperm Function ◽  
Oxygen Species

scholarly journals Spermatic mitochondria: role in oxidative homeostasis, sperm function and possible tools for their assessment

Zygote ◽  
2018 ◽  
Vol 26 (4) ◽  
pp. 251-260 ◽  
Author(s):  
João Diego de Agostini Losano ◽  
Daniel de Souza Ramos Angrimani ◽  
Roberta Ferreira Leite ◽  
Bárbara do Carmo Simões da Silva ◽  
Valquíria Hyppolito Barnabe ◽  
...  
Keyword(s):  
Reactive Oxygen Species ◽  
Mitochondrial Function ◽  
Reactive Oxygen ◽  
Sperm Function ◽  
Oxygen Species ◽  
Functional Dynamics ◽  
Fertilization Capacity ◽  
Oxidative Homeostasis

SummaryDespite sperm mitochondrial relevance to the fertilization capacity, the processes involved in the production of ATP and functional dynamics of sperm mitochondria are not fully understood. One of these processes is the paradox involved between function and formation of reactive oxygen species performed by the organelle. Therefore, this review aimed to provide data on the role of sperm mitochondria in oxidative homeostasis and functionality as well the tools to assess sperm mitochondrial function.

Free radicals, lipid peroxidation and sperm function

1995 ◽  
Vol 7 (4) ◽  
pp. 659 ◽  
Author(s):  
RJ Aitken
Keyword(s):  
Reactive Oxygen Species ◽  
Lipid Peroxidation ◽  
Reactive Oxygen ◽  
Human Spermatozoa ◽  
Sperm Function ◽  
Oxygen Species ◽  
Normal Sperm ◽  
Oxidative Processes ◽  
Mammalian Spermatozoa

The cellular generation of reactive oxygen species was first observed in mammalian spermatozoa in the late 1940s. The field then remained dormant for 30 years until Thaddeus Mann and Roy Jones published a series of landmark papers in the 1970s in which the importance of lipid peroxidation as a mechanism for damaging mammalian spermatozoa was first intimated. The subsequent demonstration that human spermatozoa produce reactive oxygen species and are susceptible to peroxidative damage has triggered intense interest in the role of oxidative stress in the aetiology of male infertility. Moreover, data have recently been obtained to indicate that, although excessive exposure to reactive oxygen species may be harmful to spermatozoa, in physiological amounts these molecules are of importance in the control of normal sperm function. This review considers the dualistic role of reactive oxygen species and sets out the current understanding of the importance of oxidative processes in both the physiology and the pathology of the human spermatozoon. Extra keywords: human spermatozoa, reactive oxygen species.

Physiological role of reactive oxygen species in testis and epididymal spermatozoa

Andrologia ◽  
2022 ◽  
Author(s):  
Lizbeth Juárez‐Rojas ◽  
Fahiel Casillas ◽  
Alma López ◽  
Miguel Betancourt ◽  
Mohammad Mehdi Ommati ◽  
...  
Keyword(s):  
Reactive Oxygen Species ◽  
Physiological Role ◽  
Reactive Oxygen ◽  
Oxygen Species ◽  
Epididymal Spermatozoa

Oxidative stress and reactive oxygen species: a review of their role in ocular disease

2017 ◽  
Vol 131 (24) ◽  
pp. 2865-2883 ◽  
Author(s):  
Lawson Ung ◽  
Ushasree Pattamatta ◽  
Nicole Carnt ◽  
Jennifer L. Wilkinson-Berka ◽  
Gerald Liew ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Reactive Oxygen Species ◽  
Cell Function ◽  
Physiological Role ◽  
Reactive Oxygen ◽  
Age Related Macular Degeneration ◽  
Current Evidence ◽  
Oxygen Species ◽  
Age Related

For many years, oxidative stress arising from the ubiquitous production of reactive oxygen species (ROS) has been implicated in the pathogenesis of various eye diseases. While emerging research has provided some evidence of the important physiological role of ROS in normal cell function, disease may arise where the concentration of ROS exceeds and overwhelms the body’s natural defence against them. Additionally, ROS may induce genomic aberrations which affect cellular homoeostasis and may result in disease. This literature review examines the current evidence for the role of oxidative stress in important ocular diseases with a view to identifying potential therapeutic targets for future study. The need is particularly pressing in developing treatments for conditions which remain notoriously difficult to treat, including glaucoma, diabetic retinopathy and age-related macular degeneration.

Biological and physiological role of reactive oxygen species - the good, the bad and the ugly

2015 ◽  
Vol 214 (3) ◽  
pp. 329-348 ◽  
Author(s):  
L. Zuo ◽  
T. Zhou ◽  
B. K. Pannell ◽  
A. C. Ziegler ◽  
T. M. Best
Keyword(s):  
Reactive Oxygen Species ◽  
Physiological Role ◽  
Reactive Oxygen ◽  
Oxygen Species

Plants as Biofactories: Physiological Role of Reactive Oxygen Species on the Accumulation of Phenolic Antioxidants in Carrot Tissue under Wounding and Hyperoxia Stress

2011 ◽  
Vol 59 (12) ◽  
pp. 6583-6593 ◽  
Author(s):  
Daniel A. Jacobo-Velázquez ◽  
Ginés B. Martínez-Hernández ◽  
Silvia del C. Rodríguez ◽  
Cong-Mei Cao ◽  
Luis Cisneros-Zevallos
Keyword(s):  
Reactive Oxygen Species ◽  
Physiological Role ◽  
Reactive Oxygen ◽  
Phenolic Antioxidants ◽  
Oxygen Species
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