1997 ◽  
Vol 9 (6) ◽  
pp. 1179-1209 ◽  
Author(s):  
M. L. Hines ◽  
N. T. Carnevale

The moment-to-moment processing of information by the nervous system involves the propagation and interaction of electrical and chemical signals that are distributed in space and time. Biologically realistic modeling is needed to test hypotheses about the mechanisms that govern these signals and how nervous system function emerges from the operation of these mechanisms. The NEURON simulation program provides a powerful and flexible environment for implementing such models of individual neurons and small networks of neurons. It is particularly useful when membrane potential is nonuniform and membrane currents are complex. We present the basic ideas that would help informed users make the most efficient use of NEURON.


2019 ◽  
Vol 17 (1) ◽  
pp. 23
Author(s):  
Ivnaini Andesgur ◽  
Imam Suprayogi ◽  
Pipi Handrianti

Daerah Aliran Sungai (DAS) Siak termasuk DAS kritis khususnya bagian hilir, dimana terjadinya penurunan debit dan kulitas air sungai yang dipicu oleh meningkatnya aktivitas disepanjang aliran sungai yang didominasi oleh kegiatan perkebunan. Penelitian ini bertujuan untuk menganalisis daya tampung beban pencemaran BOD, COD dan TSS pada DAS Siak bagian hilir menggunakan metode WASP 7.3; dan menentukan besar reduksi beban pencemarannya. DAS Siak bagian hilir dibagi menjadi 14 segment kemudian dilakukan simulasi beban pencemaran parameter BOD, COD dan TSS pada masing-masing segment. Pada simulasi ini digunakan debit minimum yaitu sebesar 151 m3/dt dilanjutkan dengan mereduksi beban pencemarannya sebesar 75%, 50% dan 25% sampai sesuai dengan baku mutu air peruntukan kelas II.  Hasil Pemodelan WASP7.3 Daya Tampung Beban Pencemaran DAS Siak bagian hilir kabupaten Siak pada debit andalan minimum masing-masing untuk parameter BOD sebesar -68.877,82 kg/hari, COD sebesar -300.242,11 kg/hari dan TSS sebesar -169.065,78 kg/hari, dimana tanda minus (-) menandakan bahwa beban pencemar melebihi daya tampung sungai. Reduksi beban pencemar untuk parameter BOD sebesar 75%, COD sebesar 50%, dan TSS sebesar 25%. Parameter BOD merupakan parameter tertinggi dilakukan reduksi karena semua segment pada DAS Siak bagian hilir kabupaten Siak melebihi baku mutu peruntukkan kelas II. Kemampuan DAS Siak bagian hilir kabupaten Siak untuk menampung beban pencemar berdasarkan baku mutu peruntukkan kelas II setelah dilakukan reduksi masing-masing parameter pencemar adalah BOD 75% sebesar 12.134,95 kg/hari, COD 50% sebesar 12.958,94 kg/hari, dan TSS 25% sebesar 36.280,66 kg/hari.


1988 ◽  
Author(s):  
David H. Root ◽  
William E. Scott
Keyword(s):  

Author(s):  
Moon-Sook Kim ◽  
Mi-Hee Seo ◽  
Jin-Young Jung ◽  
Jinhyun Kim

The purpose of this study is to develop a simulation-based ventilator training program for general ward nurses and identify its effects. Quantitative data were collected from 29 nurses (intervention group: 15, control group: 14), of which seven were interviewed with focus groups to collect qualitative data. The quantitative results revealed significant differences in ventilator-related knowledge (p = 0.029) and self-efficacy (p = 0.026) between the intervention and control groups. Moreover, three themes were derived from meaningful statements in the qualitative data: understanding psychophysical discomfort of the patient while applying the ventilator; helping in ventilator care; and establishing a future ventilator training strategy. The findings confirmed that the non-invasive positive pressure ventilation (NPPV) simulation program is an effective method for improving the knowledge of ventilator nursing and self-efficacy and will be helpful in developing educational methods and strategies related to ventilator nursing for general ward nurses.


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