Serum and Tissue Lipid Metabolism and Effect of Nicotinic Acid in Different Types of Hyperlipidemia

Author(s):  
Lars A. Carlson ◽  
Göran Walldius
2001 ◽  
Vol 44 (3) ◽  
pp. 263-267 ◽  
Author(s):  
Kelly Fabiane Santos Ricardo ◽  
Tânia Toledo de Oliveira ◽  
Tanus Jorge Nagem ◽  
Aloisio da Silva Pinto ◽  
Maria Goreti Almeida Oliveira ◽  
...  

Atherosclerosis is a coronary disease where deposition of lipids in the arteries leads to problems of blood circulation. The present work evaluates the action of the flavonoids morin, quercetin and nicotinic acid isolated in association on lipid metabolism in hyperlipidemic rats. Blood serum levels cholesterol, cholesterol-HDL, and triacylglycerids have been analysed following the intraperitoneal administration of the flavonoid compounds dissolved in propyleneglycol by in doses of 5mg/kg body weight. Quercetin presented the largest percentual reduction of cholesterol. The best results for cholesterol-HDL have been obtained with-nicotinic acid alone while morin-nicotinic acid combination showed the best triacylglycerols results. Results showed that flavonoids could be beneficious in the treatment of coronary diseases.


1988 ◽  
Vol 66 (6) ◽  
pp. 1393 ◽  
Author(s):  
C. Y. Hu ◽  
A. Suryawan ◽  
N. E. Forsberg ◽  
R. H. Dalrymple ◽  
C. A. Ricks

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