Intracerebral Expression of Transferrin Receptors in Iron-Deficient Rats

Author(s):  
T. Moos ◽  
T. M. Hansen
2004 ◽  
Vol 64 (8) ◽  
pp. 691-702 ◽  
Author(s):  
J. Starklint ◽  
J. Nørgaard Bech ◽  
O. Aagaard ◽  
E. Bjerregaard Pedersen

2013 ◽  
Vol 16 (9) ◽  
pp. 1677-1683 ◽  
Author(s):  
Mohammad Ataur Rahman ◽  
Bushra Rahman ◽  
Nessar Ahmed

AbstractObjectiveDietary Fe deficiency has a high incidence in Pakistani children and may be associated with increased gastrointestinal absorption of trace metals such as Mn. Therefore, children residing in heavily polluted cities like Karachi may be prone to Mn toxicity. The present study investigated blood Mn concentrations in Karachi children of different Fe statuses.DesignA prospective observational study was conducted where children were classified into different categories of Fe status – normal Fe, borderline Fe deficiency, Fe deficiency and Fe-deficiency anaemia – using WHO criteria supported by measurements of soluble transferrin receptors. Blood Mn was determined for children in each category using graphite atomic absorption spectroscopy.SettingThree hospital outpatient departments in Karachi, Pakistan.SubjectsA total of 269 children (156 males, 113 females) aged 6–60 months from low-income families of Karachi.ResultsBlood Mn concentrations were significantly higher in children with Fe-deficiency anaemia and Fe deficiency compared with those of normal Fe status (both P < 0·01). Blood concentrations of soluble transferrin receptors were higher in children with Fe-deficiency anaemia compared with those of borderline or normal Fe status (both P < 0·05).ConclusionsThese findings report for the first time high blood Mn concentrations in Fe-deficient children of this age group. There is therefore an urgent need to identify and remove environmental exposure to Mn in combination with health strategies aimed at eradicating childhood Fe deficiency.


1990 ◽  
Vol 36 (2) ◽  
pp. 145-147 ◽  
Author(s):  
Anthony B. Schryvers ◽  
Guido C. Gonzalez

Transferrin receptors detected by a solid-phase binding assay were shown to be specific for the host's transferrin in the representative bacterial pathogens Neisseria meningitidis (human), Pasteurella haemolytica (bovine), and Actinobacillus pleuropneumoniae (porcine). Consistent with the receptor specificity, iron-deficient bacteria were only capable of utilizing transferrin from the host as a source of iron for growth. Key words: iron, transferrin, receptor.


Pathology ◽  
1975 ◽  
Vol 7 (1) ◽  
pp. 35-44 ◽  
Author(s):  
N.D. Yeomans ◽  
D.J.B. St John

2011 ◽  
Vol 40 (12) ◽  
pp. 1720-1725
Author(s):  
Myoung-Gyu Park ◽  
Tae-Yul Ha ◽  
Kwang-Soon Shin

2010 ◽  
Vol 39 (10) ◽  
pp. 1446-1451 ◽  
Author(s):  
Hye-Jin Cho ◽  
Hyun-Sun Lee ◽  
Eun-Young Jung ◽  
So-Yeon Park ◽  
Woo-Taek Lim ◽  
...  

2019 ◽  
Author(s):  
Si Athena Chen ◽  
◽  
Peter Heaney ◽  
Jeffrey E. Post ◽  
Peter J. Eng ◽  
...  

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