Using Homogeneous Primary Neuron Cultures to Study Fundamental Aspects of HSV-1 Latency and Reactivation

2014 ◽  
pp. 167-179 ◽  
Author(s):  
Ju Youn Kim ◽  
Lora A. Shiflett ◽  
Jessica A. Linderman ◽  
Ian Mohr ◽  
Angus C. Wilson
Keyword(s):  
Primary Neuron ◽  
Hsv 1

Assembly of VP26 in herpes simplex virus-1 capsid implicated by 3-D structure of recombinant capsid

1995 ◽  
Vol 53 ◽  
pp. 840-841
Author(s):  
Z. Hong Zhou ◽  
Jing He ◽  
Joanita Jakana ◽  
J. D. Tatman ◽  
Frazer J. Rixon ◽  
...  
Keyword(s):  
Herpes Simplex Virus ◽  
Herpes Simplex ◽  
3D Structure ◽  
Structure Study ◽  
Herpes Simplex Virus 1 ◽  
Shell Proteins ◽  
Life Threatening ◽  
Infected Cells ◽  
Simplex Virus ◽  
Hsv 1

Herpes simplex virus-1 (HSV-1) is a ubiquitous virus which is implicated in diseases ranging from self-curing cold sores to life-threatening infections. The 2500 Å diameter herpes virion is composed of a glycoprotein spike containing, lipid envelope, enclosing a protein layer (the tegument) in which is embedded the capsid (which contains the dsDNA genome). The B-, and A- and C-capsids, representing different morphogenetic stages in HSV-1 infected cells, are composed of 7, and 5 structural proteins respectively. The three capsid types are organized in similar T=16 icosahedral shells with 12 pentons, 150 hexons, and 320 connecting triplexes. Our previous 3D structure study at 26 Å revealed domain features of all these structural components and suggested probable locations for the outer shell proteins, VP5, VP26, VP19c and VP23. VP5 makes up most of both pentons and hexons. VP26 appeared to bind to the VP5 subunit in hexon but not to that in penton.

HSV-1 Is Likely Cause of New Genital Infections

2005 ◽  
Vol 36 (8) ◽  
pp. 40
Author(s):  
ELIZABETH MECHCATIE
Keyword(s):  
Genital Infections ◽  
Hsv 1

Early plasmapheresis in 3 consecutive cases of choreo-athetotic movement disorder after HSV-1 encephalitis

2011 ◽  
Vol 42 (S 01) ◽  
Author(s):  
I Lanator ◽  
M Freilinger ◽  
D Csaicsich ◽  
R Seidl ◽  
MT Schmook
Keyword(s):  
Movement Disorder ◽  
Hsv 1

Expression of HSV-1 antigen in HSV-1 infected rabbit corneal cells in vitro

1987 ◽  
Vol 1 (2) ◽  
pp. 81
Author(s):  
Myung Kyoo Ko ◽  
Joon Kiu Choe ◽  
Young Tae Kim
Keyword(s):  
Infected Rabbit ◽  
Corneal Cells ◽  
Hsv 1
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