Cross Talk Between the Metabolic and Immune Systems

2014 ◽  
pp. 13-21 ◽  
Author(s):  
Namrata Tomar ◽  
Rajat K. De
Keyword(s):  
Cross Talk ◽  
Immune Systems

Neurotrophic cross-talk between the nervous and immune systems: Implications for neurological diseases

2003 ◽  
Vol 53 (3) ◽  
pp. 292-304 ◽  
Author(s):  
Martin Kerschensteiner ◽  
Christine Stadelmann ◽  
Georg Dechant ◽  
Hartmut Wekerle ◽  
Reinhard Hohlfeld
Keyword(s):  
Cross Talk ◽  
Neurological Diseases ◽  
Immune Systems

scholarly journals Type IV CRISPR–Cas systems are highly diverse and involved in competition between plasmids

2019 ◽  
Vol 48 (4) ◽  
pp. 2000-2012 ◽  
Author(s):  
Rafael Pinilla-Redondo ◽  
David Mayo-Muñoz ◽  
Jakob Russel ◽  
Roger A Garrett ◽  
Lennart Randau ◽  
...  
Keyword(s):  
Cross Talk ◽  
Biological Function ◽  
Comprehensive Analysis ◽  
Type I ◽  
Immune Functions ◽  
Immune Systems ◽  
Gene Cassettes ◽  
Adaptive Immune ◽  
Type Iv

Abstract CRISPR–Cas systems provide prokaryotes with adaptive immune functions against viruses and other genetic parasites. In contrast to all other types of CRISPR–Cas systems, type IV has remained largely overlooked. Here, we describe a previously uncharted diversity of type IV gene cassettes, primarily encoded by plasmid-like elements from diverse prokaryotic taxa. Remarkably, via a comprehensive analysis of their CRISPR spacer content, these systems were found to exhibit a strong bias towards the targeting of other plasmids. Our data indicate that the functions of type IV systems have diverged from those of other host-related CRISPR–Cas immune systems to adopt a role in mediating conflicts between plasmids. Furthermore, we find evidence for cross-talk between certain type IV and type I CRISPR–Cas systems that co-exist intracellularly, thus providing a simple answer to the enigmatic absence of type IV adaptation modules. Collectively, our results lead to the expansion and reclassification of type IV systems and provide novel insights into the biological function and evolution of these elusive systems.

Cross talk between induced plant immune systems.

2009 ◽  
pp. 163-178
Author(s):  
R. González-Lamothe ◽  
M. El-Oirdi ◽  
T. A. El-Rahman ◽  
R. Sansregret ◽  
H. Bathily ◽  
...  
Keyword(s):  
Cross Talk ◽  
Immune Systems

scholarly journals Communication Between the Microbiota and Mammalian Immunity

2018 ◽  
Vol 72 (1) ◽  
pp. 399-422 ◽  
Author(s):  
Kyla S. Ost ◽  
June L. Round
Keyword(s):  
Adaptive Immunity ◽  
Cross Talk ◽  
Life Forms ◽  
Host Immunity ◽  
Host Responses ◽  
Immune Systems ◽  
Classical Studies ◽  
Diverse World ◽  
The Cross

Mammalian immune systems evolved within a diverse world dominated by microbes, making interactions between these two life-forms inevitable. Adaptive immunity protects against microbes through antigen-specific responses. In classical studies, these responses were investigated in the context of pathogenicity; however, we now know that they have significant effects on our resident microbes. In turn, microbes employ an arsenal of mechanisms to influence development and specificity of host immunity. Understanding these complex reactions will be necessary to develop microbiota-based strategies to prevent or treat disease. Here we review the literature detailing the cross talk between resident microbes with a focus on the specificity of host responses and the microbial molecules that influence them.

Immune Systems of HIV Patients Age More Rapidly

2010 ◽  
Vol 43 (1) ◽  
pp. 54
Author(s):  
SHERRY BOSCHERT
Keyword(s):  
Hiv Patients ◽  
Immune Systems

„Cross-talk“ zwischen Herz und Niere – das Kardiorenale Syndrom und seine Therapie aus der Sicht des Nephrologen

2009 ◽  
Vol 66 (11) ◽  
pp. 741-746 ◽  
Author(s):  
Stefan Farese
Keyword(s):  
Cross Talk

Herz und Nierenfunktion sind eng miteinander verknüpft. Ein Großteil der Patienten mit chronischer Herzinsuffizienz leidet gleichzeitig an einer Nierenfunktionsstörung. Diese ist kausal an der Entwicklung der Herzinsuffizienz beteiligt und stellt damit einen wichtigen prognostischen Faktor dar. Pathophysiologisch kommt es durch die verminderte renale Perfusion zu einer Aktivierung verschiedener Regelkreise, die eine Salz- und Wasserretention induzieren und damit das Fortschreiten der Herzinsuffizienz begünstigen. Therapeutische Ziele sind die Euvolämie sowie die kontrollierte Behandlung mittels prognostisch relevanter, kardialer Begleitmedikation. Können diese beiden Ziele aufgrund von Therapieresistenz, progredienter Niereninsuffizienz oder Therapie-Nebenwirkungen nicht erreicht werden, ist die Indikation für ein Nierenersatzverfahren gegeben. Prinzipiell können alle heute verfügbaren Verfahren angewendet werden. Die Auswahl der Modalität sollte jedoch an die individuelle Situation des Patienten angepasst und interdisziplinär besprochen werden. Obwohl sich unter Therapie bei allen Nierenersatzverfahren funktionelle und subjektive Verbesserungen nachweisen lassen, ist deren Einfluss auf die Langzeitprognose ungeklärt.

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