Use of Human Fallopian Tube Organ in Culture (FTOC) and Primary Fallopian Tube Epithelial Cells (FTEC) to Study the Biology of Neisseria gonorrhoeae Infection

2019 ◽  
pp. 377-402 ◽  
Author(s):  
A. Said Álamos-Musre ◽  
Alejandro Escobar ◽  
Cecilia V. Tapia ◽  
Myron Christodoulides ◽  
Paula I. Rodas
Keyword(s):  
Epithelial Cells ◽  
Neisseria Gonorrhoeae ◽  
Fallopian Tube ◽  
Human Fallopian Tube

scholarly journals Differential intracellular efficacies of ciprofloxacin and cefixime against Neisseria gonorrhoeae in human fallopian tube organ culture.

1997 ◽  
Vol 41 (7) ◽  
pp. 1547-1551 ◽  
Author(s):  
J P Phanucharas ◽  
G L Gorby
Keyword(s):  
Epithelial Cells ◽  
Confidence Interval ◽  
Neisseria Gonorrhoeae ◽  
Organ Culture ◽  
Fallopian Tube ◽  
Cytochalasin D ◽  
Human Fallopian Tube ◽  
Culture Model ◽  
Better Than

This study compared the abilities of ciprofloxacin and cefixime to kill intracellular Neisseria gonorrhoeae in a human fallopian tube organ culture assay. When invasion was inhibited by cytochalasin D, 0.996% of the tissue-associated gonococci survived ciprofloxacin exposure compared to 1.70% of gonococci exposed to cefixime (95% confidence interval for the ratio of the means, 0.267 to 1.30), indicating that the two antibiotics did not significantly differ in the ability to kill extracellular attached organisms. In the absence of cytochalasin D, 1.63% survived ciprofloxacin exposure while 9.76% survived cefixime treatment (95% confidence interval for the ratio of the means, 0.067 to 0.418). These results suggest that ciprofloxacin penetrated epithelial cells and killed intracellular gonococci better than did cefixime. Thus, at concentrations achievable in serum, ciprofloxacin was more effective in total gonococcal killing than cefixime in this human fallopian tube organ culture model.

scholarly journals Antiviral responses of human Fallopian tube epithelial cells to toll-like receptor 3 agonist poly(I:C)

2008 ◽  
Vol 89 (5) ◽  
pp. 1497-1506 ◽  
Author(s):  
Mimi Ghosh ◽  
Todd M. Schaefer ◽  
John V. Fahey ◽  
Jacqueline A. Wright ◽  
Charles R. Wira
Keyword(s):  
Epithelial Cells ◽  
Fallopian Tube ◽  
Poly I:C ◽  
Toll Like Receptor ◽  
Antiviral Responses ◽  
Human Fallopian Tube

Isolation and monolayer culture of human fallopian tube epithelial cells

1991 ◽  
Vol 27 (9) ◽  
pp. 720-724 ◽  
Author(s):  
Kazuhiro Takeuchi ◽  
Ikuro Maruyama ◽  
Sinichi Yamamoto ◽  
Toshimichi Oki ◽  
Yukihiro Nagata
Keyword(s):  
Epithelial Cells ◽  
Fallopian Tube ◽  
Monolayer Culture ◽  
Human Fallopian Tube

Toxic Activity of Purified Lipopolysaccharide of Neisseria gonorrhoeae for Human Fallopian Tube Mucosa

1981 ◽  
Vol 143 (3) ◽  
pp. 432-439 ◽  
Author(s):  
C. R. Gregg ◽  
M. A. Melly ◽  
C. G. Hellerqvist ◽  
J. G. Coniglio ◽  
Z. A. McGee
Keyword(s):  
Neisseria Gonorrhoeae ◽  
Fallopian Tube ◽  
Toxic Activity ◽  
Human Fallopian Tube

scholarly journals Variable localization of Toll-like receptors in human fallopian tube epithelial cells

2018 ◽  
Vol 45 (1) ◽  
pp. 1-9 ◽  
Author(s):  
Fatemehsadat Amjadi ◽  
Zahra Zandieh ◽  
Ensieh Salehi ◽  
Reza Jafari ◽  
Nasrin Ghasemi ◽  
...  
Keyword(s):  
Epithelial Cells ◽  
Fallopian Tube ◽  
Toll Like Receptors ◽  
Human Fallopian Tube

scholarly journals Role of miR-182 in response to oxidative stress in the cell fate of human fallopian tube epithelial cells

Oncotarget ◽  
2015 ◽  
Vol 6 (36) ◽  
pp. 38983-38998 ◽  
Author(s):  
Yugang Liu ◽  
Wenan Qiang ◽  
Xiaofei Xu ◽  
Ruifen Dong ◽  
Alison M. Karst ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Epithelial Cells ◽  
Cell Fate ◽  
Fallopian Tube ◽  
Human Fallopian Tube
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