The Use of Phage Display Peptide Libraries for Basic and Translational Research

2007 ◽  
pp. 203-213 ◽  
Author(s):  
Renee Brissette ◽  
Neil I. Goldstein
Keyword(s):  
Phage Display ◽  
Translational Research ◽  
Peptide Libraries

Mimotopes of polyreactive anti-DNA antibodies identified using phage-display peptide libraries

1997 ◽  
Vol 27 (5) ◽  
pp. 1221-1228 ◽  
Author(s):  
Pierre Sibille ◽  
Thérèse Ternynck ◽  
Faridabano Nato ◽  
Gérard Buttin ◽  
Donny Strosberg ◽  
...  
Keyword(s):  
Phage Display ◽  
Peptide Libraries ◽  
Dna Antibodies

scholarly journals Phage Display of Combinatorial Peptide Libraries: Application to Antiviral Research

Molecules ◽  
2011 ◽  
Vol 16 (5) ◽  
pp. 3499-3518 ◽  
Author(s):  
Guillaume Castel ◽  
Mohamed Chtéoui ◽  
Bernadette Heyd ◽  
Noël Tordo
Keyword(s):  
Phage Display ◽  
Peptide Libraries ◽  
Combinatorial Peptide Libraries

Analyte Peptidomimetics Selected from Phage Display Peptide Libraries:  A Systematic Strategy for the Development of Environmental Immunoassays

2005 ◽  
Vol 39 (11) ◽  
pp. 4234-4241 ◽  
Author(s):  
Soledad Cardozo ◽  
Andrés González-Techera ◽  
Jerold A. Last ◽  
Bruce D. Hammock ◽  
Karl Kramer ◽  
...  
Keyword(s):  
Phage Display ◽  
Peptide Libraries ◽  
Systematic Strategy

scholarly journals SAROTUP: Scanner and Reporter of Target-Unrelated Peptides

2010 ◽  
Vol 2010 ◽  
pp. 1-7 ◽  
Author(s):  
Jian Huang ◽  
Beibei Ru ◽  
Shiyong Li ◽  
Hao Lin ◽  
Feng-Biao Guo
Keyword(s):  
Phage Display ◽  
Epitope Mapping ◽  
Surface Display ◽  
Epitope Prediction ◽  
Peptide Libraries ◽  
Screening System ◽  
Web Tool ◽  
Random Peptide ◽  
Random Peptide Libraries ◽  
Convenient Approach

As epitope mimics, mimotopes have been widely utilized in the study of epitope prediction and the development of new diagnostics, therapeutics, and vaccines. Screening the random peptide libraries constructed with phage display or any other surface display technologies provides an efficient and convenient approach to acquire mimotopes. However, target-unrelated peptides creep into mimotopes from time to time through binding to contaminants or other components of the screening system. In this study, we present SAROTUP, a free web tool for scanning, reporting and excluding possible target-unrelated peptides from real mimotopes. Preliminary tests show that SAROTUP is efficient and capable of improving the accuracy of mimotope-based epitope mapping. It is also helpful for the development of mimotope-based diagnostics, therapeutics, and vaccines.

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