Study on Flow-Focusing Microfluidic Device with External Electric Field for Droplet Generation

2018 ◽  
pp. 553-559
Author(s):  
Cuong Nguyen Nhu ◽  
Hang Nguyen Thu ◽  
Luan Le Van ◽  
Trinh Chu Duc ◽  
Van Thanh Dau ◽  
...  
Keyword(s):  
Electric Field ◽  
External Electric Field ◽  
Microfluidic Device ◽  
Droplet Generation ◽  
Flow Focusing

scholarly journals Negative Pressure Provides Simple and Stable Droplet Generation in a Flow-Focusing Microfluidic Device

Micromachines ◽  
2021 ◽  
Vol 12 (6) ◽  
pp. 662
Author(s):  
Nikita A. Filatov ◽  
Anatoly A. Evstrapov ◽  
Anton S. Bukatin
Keyword(s):  
Microfluidic Device ◽  
Negative Pressure ◽  
Low Cost ◽  
Control Valve ◽  
Droplet Microfluidics ◽  
Droplet Generation ◽  
Electric Signal ◽  
Absolute Pressure ◽  
Flow Focusing ◽  
Wide Range

Droplet microfluidics is an extremely useful and powerful tool for industrial, environmental, and biotechnological applications, due to advantages such as the small volume of reagents required, ultrahigh-throughput, precise control, and independent manipulations of each droplet. For the generation of monodisperse water-in-oil droplets, usually T-junction and flow-focusing microfluidic devices connected to syringe pumps or pressure controllers are used. Here, we investigated droplet-generation regimes in a flow-focusing microfluidic device induced by the negative pressure in the outlet reservoir, generated by a low-cost mini diaphragm vacuum pump. During the study, we compared two ways of adjusting the negative pressure using a compact electro-pneumatic regulator and a manual airflow control valve. The results showed that both types of regulators are suitable for the stable generation of monodisperse droplets for at least 4 h, with variations in diameter less than 1 µm. Droplet diameters at high levels of negative pressure were mainly determined by the hydrodynamic resistances of the inlet microchannels, although the absolute pressure value defined the generation frequency; however, the electro-pneumatic regulator is preferable and convenient for the accurate control of the pressure by an external electric signal, providing more stable pressure, and a wide range of droplet diameters and generation frequencies. The method of droplet generation suggested here is a simple, stable, reliable, and portable way of high-throughput production of relatively large volumes of monodisperse emulsions for biomedical applications.

scholarly journals Droplet Generation in a Flow-Focusing Microfluidic Device with External Mechanical Vibration

Micromachines ◽  
2020 ◽  
Vol 11 (8) ◽  
pp. 743
Author(s):  
Zhaoqin Yin ◽  
Zemin Huang ◽  
Xiaohui Lin ◽  
Xiaoyan Gao ◽  
Fubing Bao
Keyword(s):  
Microfluidic Device ◽  
Vibration Frequency ◽  
Linear Correlation ◽  
Vibration Amplitude ◽  
Mechanical Vibration ◽  
Droplet Generation ◽  
Flow Focusing ◽  
Generation Frequency ◽  
External Vibration ◽  
Shrinkage Process

The demand for highly controllable droplet generation methods is very urgent in the medical, materials, and food industries. The droplet generation in a flow-focusing microfluidic device with external mechanical vibration, as a controllable droplet generation method, is experimentally studied. The effects of vibration frequency and acceleration amplitude on the droplet generation are characterized. The linear correlation between the droplet generation frequency and the external vibration frequency and the critical vibration amplitude corresponding to the imposing vibration frequency are observed. The droplet generation frequency with external mechanical vibration is affected by the natural generation frequency, vibration frequency, and vibration amplitude. The droplet generation frequency in a certain microfluidic device with external vibration is able to vary from the natural generation frequency to the imposed vibration frequency at different vibration conditions. The evolution of dispersed phase thread with vibration is remarkably different with the process without vibration. Distinct stages of expansion, shrinkage, and collapse are observed in the droplet formation with vibration, and the occurrence number of expansion–shrinkage process is relevant with the linear correlation coefficient.

Control of the breakup process of viscous droplets by an external electric field inside a microfluidic device

Soft Matter ◽  
2015 ◽  
Vol 11 (19) ◽  
pp. 3884-3899 ◽  
Author(s):  
Yuehao Li ◽  
Mranal Jain ◽  
Yongting Ma ◽  
Krishnaswamy Nandakumar
Keyword(s):  
Electric Field ◽  
External Electric Field ◽  
Microfluidic Device ◽  
Microfluidic Devices ◽  
Breakup Process ◽  
Viscous Droplets

Microfluidic devices incorporated with external electric field have demonstrated their capabilities in controlling the breakup process of viscous droplets where conventional microfluidics is ineffective.

scholarly journals Controlled production of emulsion drops using an electric field in a flow-focusing microfluidic device

2007 ◽  
Vol 91 (13) ◽  
pp. 133106 ◽  
Author(s):  
Haejune Kim ◽  
Dawei Luo ◽  
Darren Link ◽  
David A. Weitz ◽  
Manuel Marquez ◽  
...  
Keyword(s):  
Electric Field ◽  
Microfluidic Device ◽  
Flow Focusing ◽  
Emulsion Drops

SURFACE STATES AND ADSORPTION IN AN EXTERNAL ELECTRIC FIELD

1984 ◽  
Vol 45 (C9) ◽  
pp. C9-65-C9-70
Author(s):  
M. Stwślicka ◽  
M. Radny
Keyword(s):  
Electric Field ◽  
External Electric Field ◽  
Surface States

Time-resolved X-ray reciprocal space mapping of the crystal under external electric field

2018 ◽  
Vol 189 (02) ◽  
pp. 187-194 ◽  
Author(s):  
Nikita V. Marchenkov ◽  
Anton G. Kulikov ◽  
Ivan I. Atknin ◽  
Arsen A. Petrenko ◽  
Alexander E. Blagov ◽  
...  
Keyword(s):  
Electric Field ◽  
External Electric Field ◽  
Space Mapping ◽  
Reciprocal Space ◽  
Reciprocal Space Mapping ◽  
Time Resolved ◽  
X Ray
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