Intensity Standardization of Skeleton in Follow-Up Whole-Body MRI

2019 ◽  
pp. 77-89
Author(s):  
Jakub Ceranka ◽  
Sabrina Verga ◽  
Frédéric Lecouvet ◽  
Thierry Metens ◽  
Johan de Mey ◽  
...  
Keyword(s):  
Whole Body ◽  
Whole Body Mri

scholarly journals NIMG-66. LONG-TERM FOLLOW-UP OF NEUROFIBROMATOSIS TYPE 1 PATIENTS USING WHOLE-BODY MRI DEMONSTRATES DYNAMIC CHANGES IN INTERNAL NEUROFIBROMA SIZE

2019 ◽  
Vol 21 (Supplement_6) ◽  
pp. vi176-vi176
Author(s):  
Ina Ly ◽  
Raquel Thalheimer ◽  
Wenli Cai ◽  
Miriam Bredella ◽  
Vanessa Merker ◽  
...  
Keyword(s):  
Tumor Growth ◽  
Neurofibromatosis Type 1 ◽  
Neurofibromatosis Type ◽  
Whole Body ◽  
Childhood And Adolescence ◽  
Entire Study ◽  
Whole Body Mri

Abstract BACKGROUND Neurofibromas affect 40–50% of neurofibromatosis type 1 (NF1) patients and can cause significant morbidity and mortality. They grow more rapidly during childhood and adolescence but studies in adults are limited by their retrospective nature and follow-up time < 3 years. The long-term natural history of neurofibromas remains unknown. No guidelines exist on the need and frequency of surveillance imaging for patients. Whole-body MRI (WBMRI) can detect whole-body tumor burden, including internal neurofibromas. METHODS 17 adult NF1 patients who underwent WBMRI between 2007–2010 (Scan 1) underwent repeat WBMRI between 2018–2019 (Scan 2). Internal neurofibromas were segmented on short tau inversion recovery (STIR) sequences and tumor volume was calculated using a computerized volumetry and three-dimensional segmentation software. Circumscribed tumors were defined as discrete; invasive tumors or those involving multiple nerves were defined as plexiform. Tumor growth and shrinkage were defined as volume change ≥ 20% over the entire study period. RESULTS Median patient age was 43 years during Scan 1 and 53 years during Scan 2. Median time between Scan 1 and 2 was 9 years. A total of 140 neurofibromas were assessed. 24% of tumors grew by a median 63% (6.8% per year). 54% of tumors spontaneously decreased in volume by a median 60% (7% per year) without treatment. On a per-patient basis, 18% of patients had overall tumor growth and 41% overall tumor shrinkage. 8 new tumors developed in 7 patients. 16 tumors resolved entirely without medical or surgical intervention. Growth behavior did not correlate with discrete or plexiform morphology. CONCLUSION A subset of internal neurofibromas in adult NF1 patients grow significantly over a long-term period, suggesting that continued monitoring of these patients may be warranted. Surprisingly, more than half of neurofibromas shrink spontaneously without intervention. Continued patient enrollment and correlation of imaging findings with functional outcomes are underway.

scholarly journals Clinical Evaluation of an Abbreviated Contrast-Enhanced Whole-Body MRI for Oncologic Follow-Up Imaging

Diagnostics ◽  
2021 ◽  
Vol 11 (12) ◽  
pp. 2368
Author(s):  
Judith Herrmann ◽  
Saif Afat ◽  
Andreas Brendlin ◽  
Maryanna Chaika ◽  
Andreas Lingg ◽  
...  
Keyword(s):  
Image Quality ◽  
Random Order ◽  
Whole Body ◽  
Diagnostic Confidence ◽  
Whole Body Mri ◽  
Institutional Review ◽  
Contrast Enhanced ◽  
Mri Protocol ◽  
Cancer Types

Over the last decades, overall survival for most cancer types has increased due to earlier diagnosis and more effective treatments. Simultaneously, whole-body MRI-(WB-MRI) has gained importance as a radiation free staging alternative to computed tomography. The aim of this study was to evaluate the diagnostic confidence and reproducibility of a novel abbreviated 20-min WB-MRI for oncologic follow-up imaging in patients with melanoma. In total, 24 patients with melanoma were retrospectively included in this institutional review board-approved study. All patients underwent three consecutive staging examinations via WB-MRI in a clinical 3 T MR scanner with an abbreviated 20-min protocol. Three radiologists independently evaluated the images in a blinded, random order regarding image quality (overall image quality, organ-based image quality, sharpness, noise, and artifacts) and regarding its diagnostic confidence on a 5-point-Likert-Scale (5 = excellent). Inter-reader agreement and reproducibility were assessed. Overall image quality and diagnostic confidence were rated to be excellent (median 5, interquartile range [IQR] 5–5). The sharpness of anatomic structures, and the extent of noise and artifacts, as well as the assessment of lymph nodes, liver, bone, and the cutaneous system were rated to be excellent (median 5, IQR 4–5). The image quality of the lung was rated to be good (median 4, IQR 4–5). Therefore, our study demonstrated that the novel accelerated 20-min WB-MRI protocol is feasible, providing high image quality and diagnostic confidence with reliable reproducibility for oncologic follow-up imaging.

scholarly journals Whole-Body MRI in Rheumatology: Major Advances and Future Perspectives

Diagnostics ◽  
2021 ◽  
Vol 11 (10) ◽  
pp. 1770
Author(s):  
Luca Deplano ◽  
Matteo Piga ◽  
Michele Porcu ◽  
Alessandro Stecco ◽  
Jasjit S. Suri ◽  
...  
Keyword(s):  
Pediatric Population ◽  
Standard Technique ◽  
Chronic Recurrent Multifocal Osteomyelitis ◽  
Whole Body ◽  
Whole Body Mri ◽  
Treatment Response Evaluation ◽  
Multifocal Osteomyelitis ◽  
Body Magnetic Resonance Imaging ◽  
Juvenile Spondyloarthritis

Whole-body magnetic resonance imaging is constantly gaining more importance in rheumatology, particularly for what concerns the diagnosis, follow-up, and treatment response evaluation. Initially applied principally for the study of ankylosing spondylitis, in the last years, its use has been extended to several other rheumatic diseases. Particularly in the pediatric population, WB-MRI is rapidly becoming the gold-standard technique for the diagnosis and follow-up of both chronic recurrent multifocal osteomyelitis and juvenile spondyloarthritis. In this review, we analyze the benefits and limits of this technique as well as possible future applications.

Early detection of metastases using whole-body MRI for initial staging and routine follow-up of myxoid liposarcoma

2017 ◽  
Vol 47 (3) ◽  
pp. 369-379 ◽  
Author(s):  
Natalia Gorelik ◽  
Santhosh Mauvva Venkatesh Reddy ◽  
Robert E. Turcotte ◽  
Krista Goulding ◽  
Sungmi Jung ◽  
...  
Keyword(s):  
Early Detection ◽  
Myxoid Liposarcoma ◽  
Whole Body ◽  
Whole Body Mri ◽  
Initial Staging

Subcutaneous panniculitis-like T-cell lymphoma in a child: whole-body MRI in the initial and follow-up evaluations

2008 ◽  
Vol 39 (1) ◽  
pp. 57-61 ◽  
Author(s):  
Gye-Yeon Lim ◽  
Seung Tae Hahn ◽  
Nak Gyun Chung ◽  
Hack Ki Kim
Keyword(s):  
T Cell ◽  
Cell Lymphoma ◽  
T Cell Lymphoma ◽  
Whole Body ◽  
Whole Body Mri

scholarly journals Semi-Automatic MRI Muscle Volumetry to Diagnose and Monitor Hereditary and Acquired Polyneuropathies

2021 ◽  
Vol 11 (2) ◽  
pp. 202
Author(s):  
Friederike S. Bähr ◽  
Burkhard Gess ◽  
Madlaine Müller ◽  
Sandro Romanzetti ◽  
Michael Gadermayr ◽  
...  
Keyword(s):  
Chronic Inflammatory Demyelinating Polyneuropathy ◽  
Spin Echo ◽  
Whole Body ◽  
Whole Body Mri ◽  
Charcot Marie Tooth Disease ◽  
Leg Muscles ◽  
One Year ◽  
Magnet Resonance ◽  
Tooth Disease

With emerging treatment approaches, it is crucial to correctly diagnose and monitor hereditary and acquired polyneuropathies. This study aimed to assess the validity and accuracy of magnet resonance imaging (MRI)-based muscle volumetry.Using semi-automatic segmentations of upper- and lower leg muscles based on whole-body MRI and axial T1-weighted turbo spin-echo sequences, we compared and correlated muscle volumes, and clinical and neurophysiological parameters in demyelinating Charcot-Marie-Tooth disease (CMT) (n = 13), chronic inflammatory demyelinating polyneuropathy (CIDP) (n = 27), and other neuropathy (n = 17) patients.The muscle volumes of lower legs correlated with foot dorsiflexion strength (p < 0.0001), CMT Neuropathy Score 2 (p < 0.0001), early gait disorders (p = 0.0486), and in CIDP patients with tibial nerve conduction velocities (p = 0.0092). Lower (p = 0.0218) and upper (p = 0.0342) leg muscles were significantly larger in CIDP compared to CMT patients. At one-year follow-up (n = 15), leg muscle volumes showed no significant decrease.MRI muscle volumetry is a promising method to differentiate and characterize neuropathies in clinical practice.

scholarly journals Whole-body MRI in the diagnosis of paediatric CNO/CRMO

Rheumatology ◽  
2020 ◽  
Vol 59 (10) ◽  
pp. 2671-2680 ◽  
Author(s):  
Savvas Andronikou ◽  
Jeannette K Kraft ◽  
Amaka C Offiah ◽  
Jeremy Jones ◽  
Hassan Douis ◽  
...  
Keyword(s):  
Chronic Recurrent Multifocal Osteomyelitis ◽  
Bisphosphonate Therapy ◽  
Whole Body ◽  
Inflammatory Disorder ◽  
Whole Body Mri ◽  
Spine Imaging ◽  
Multifocal Osteomyelitis ◽  
Hands And Feet ◽  
Short Tau Inversion Recovery

Abstract Chronic recurrent multifocal osteomyelitis (CRMO) is an auto-inflammatory disorder affecting the skeleton of children and adolescents. Whole-body MRI (WBMRI) is key in the diagnosis and follow-up of CRMO. Imaging protocols should include sagittal short Tau inversion recovery of the spine, imaging of the hands and feet, and T1 images for distinguishing normal bone marrow. CRMO lesions can be metaphyseal, epiphyseal and physeal—potentially causing growth disturbance and deformity. Spinal lesions are common, important and can cause vertebral collapse. Lesion patterns include multifocal tibial and pauci-focal patterns that follow a predictable presentation and course of disease. Common pitfalls of WBMRI include haematopoietic marrow signal, metaphyseal signal early on in bisphosphonate therapy and normal high T2 signal in the hands and feet. Pictorial reporting assists in recording lesions and follow-up over time. The purpose of this paper is to review the different WBMRI protocols, imaging findings, lesion patterns and common pitfalls in children with CRMO

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