Methods for Personalised Delivery Rate Computation for IV Administered Anesthetic Propofol

2019 ◽  
pp. 369-397
Author(s):  
Alena Simalatsar ◽  
Monia Guidi ◽  
Pierre Roduit ◽  
Thierry Buclin
Keyword(s):  
Delivery Rate

High dose vs. low dose oxytocin for labor augmentation: a systematic review and meta-analysis of randomized controlled trials

2020 ◽  
Vol 0 (0) ◽  
Author(s):  
Rehab Abdelhamid Aboshama ◽  
Ahmed Mohamed Abdelhakim ◽  
Mohammad Abrar Shareef ◽  
Abdulhadi A. AlAmodi ◽  
Mohammad Sunoqrot ◽  
...  
Keyword(s):  
Cesarean Delivery ◽  
Low Dose ◽  
Delivery Rate ◽  
Cochrane Library ◽  
High Dose ◽  
Safety And Efficacy ◽  
Labor Duration ◽  
Uterine Hyperstimulation ◽  
Cesarean Delivery Rate ◽  
Labor Augmentation

AbstractObjectivesTo compare the safety and efficacy between high dose and low dose oxytocin administration for labor augmentation.MethodsWe searched for the available studies during March 2020 in PubMed, Cochrane Library, Scopus, and ISI Web of science. All randomized clinical trials (RCTs) that assessed safety and efficacy of high dose vs. low dose oxytocin for labor augmentation were considered. The extracted data were entered into RevMan software. Dichotomous and continuous data were pooled as odds ratio (OR) and mean difference (MD) respectively, with the corresponding 95% confidence intervals (CI). Our main outcomes were cesarean delivery rate, spontaneous vaginal delivery rate, uterine hyperstimulation and tachysystole, and labor duration from oxytocin infusion.ResultsEight RCTs with 3,154 patients were included. High dose oxytocin did not reduce cesarean delivery rate compared to low dose oxytocin (OR=0.76, 95% CI [0.52, 1.10], p=0.15). After solving the reported heterogeneity, high dose oxytocin did not increase the rate of spontaneous vaginal deliveries vs. low dose oxytocin (OR=1.06, 95% CI [0.84, 1.32], p=0.64). Low dose oxytocin was linked to a significant decline in uterine hyperstimulation and tachysystole (p>0.001). A reduction in labor duration was found in high dose oxytocin group over low oxytocin regimen (MD=−1.02 h, 95% CI [−1.77, −0.27], p=0.008).ConclusionsWe found no advantages for high dose oxytocin over low dose oxytocin in labor augmentation except in reducing labor duration. Low dose oxytocin is safer as it decreases the incidence of uterine hyperstimulation and tachysystole. More trials are needed to confirm our findings.

In-crisis delivery rate: a novel measure of success in communal water management

2012 ◽  
Vol 11 (1-4) ◽  
pp. 503-511 ◽  
Author(s):  
Taro Takahashi ◽  
Hideo Aizaki ◽  
Takeshi Sato ◽  
Na Guo ◽  
Yasuhiro Nakashima ◽  
...  
Keyword(s):  
Water Management ◽  
Delivery Rate

Slow vs Rapid Delivery Rate Shock Wave Lithotripsy for Pediatric Renal Urolithiasis: A Prospective Randomized Study

2014 ◽  
Vol 191 (5) ◽  
pp. 1370-1374 ◽  
Author(s):  
Hosni Khairy Salem ◽  
Hesham Fathy ◽  
Hanny ElFayoumy ◽  
Hussein Aly ◽  
Ahmed Ghonium ◽  
...  
Keyword(s):  
Shock Wave ◽  
Shock Wave Lithotripsy ◽  
Randomized Study ◽  
Delivery Rate ◽  
Prospective Randomized Study

P–575 Patients with recurrent implantation failures (RIF): chromosome abnormalities in the resulting embryos

2021 ◽  
Vol 36 (Supplement_1) ◽  
Author(s):  
C Albanese ◽  
D Perruzza ◽  
C Tabanelli ◽  
S Sgargi ◽  
M C Magli ◽  
...  
Keyword(s):  
Live Birth ◽  
Uterine Cavity ◽  
Implantation Rate ◽  
Normal Karyotype ◽  
Great Majority ◽  
Chromosome Analysis ◽  
Delivery Rate ◽  
Comparative Genomic ◽  
Male Factor ◽  
Preimplantation Genetic Testing

Abstract Study question Do RIF patients have the preimplantation genetic testing for aneuploidy (PGT-A) overcome their infertility condition? Summary answer PGT-A positively impact on implantation rate in RIF patients What is known already The most common definition of RIF is failure to achieve a pregnancy after three consecutive transfers of good quality embryos. This term possibly represents a heterogeneous category of infertile couples as the causes of repeated failures can be diverse. Especially intriguing is the case of patients with an age lower than 39 years for which the oocyte quality is expected not to be compromised by the well known age effect on female fertility. The chromosome analysis of the resulting embryos has been proposed as a valid method to improve implantation in the great majority of RIF patients Study design, size, duration This retrospective study included 49 patients with at least three previous consecutive implantation failures, which underwent PGT-A from January 2016 to April 2020. Both partners had a normal karyotype. Only patients with a female age below 39 years were included, who presented with a normal uterine cavity. Couples with a severe male factor were excluded. Single frozen blastocysts were transferred according to chromosomal results Participants/materials, setting, methods Maternal age was 35.5 ± 3.1 years. All blastocysts were vitrified after trophectoderm biopsy. Whole genome amplification and array comparative genomic hybridization were performed on biopsies. Only euploid embryos were transferred. The primary outcome was the live-birth delivery rate after the first transfer Main results and the role of chance Before starting a PGT-A cycle, these patients underwent 213 embryo transfers with 251 embryos replaced. A total of 264 blastocysts were analyzed, 140 of which were aneuploid (53%). Monosomy or trisomy was reported in 67 of the diagnosed samples (67/140, 48%) whereas the remaining 73 carried complex aneuploidies (73/140, 52%). The remaining 124 blastocysts (47%) were diagnosed as euploid. All patients performed an embryo transfer resulting in 28 clinical pregnancies (57%). There were 5 spontaneous abortions and the live-birth delivery rate per patient was 47% Limitations, reasons for caution This study suffers from the weakness related to retrospectivity. In addition, as euploid embryos are still cryopreserved, the delivery rate could change at completion of the cycles Wider implications of the findings: A RIF condition can be attributed, at least in a good proportion of cases, to the generation of high percentages of aneuploid embryos. In this case, the transfer of euploid blastocysts has high chances to classify this category of RIF patients has having an embryonic cause of infertilit. Trial registration number Not applicable

scholarly journals Comparison of oral, vaginal and sublingual misoprostol for induction of labour in premature rupture of membranes after 34 weeks of gestation: a randomized controlled trial

2018 ◽  
Vol 7 (4) ◽  
pp. 1340
Author(s):  
Chandana Galidevara ◽  
Latha Chaturvedula ◽  
Syed Habeebullah
Keyword(s):  
Apgar Score ◽  
Induction Of Labour ◽  
Delivery Rate ◽  
Labour Induction ◽  
Premature Rupture Of Membranes ◽  
Premature Rupture ◽  
Routes Of Administration ◽  
Active Labour ◽  
Significant Difference ◽  
Sublingual Misoprostol

Background: Purpose of this study was to evaluate the efficacy and safety of different routes of administration of misoprostol - 50µg oral, 25µg vaginal and 50µg sublingual for induction of labour in women with premature rupture of membranes after 34 weeks of gestation.Methods: Women admitted to labour ward with premature rupture of membranes (PROM) after 34 weeks of gestation and requiring induction of labour were randomized into three groups. A total of 246 women participated in the study and were assigned to three groups to receive either 50µg oral misoprostol (n=80) or 25µg vaginal misoprostol(n=83) or 50µg sublingual misoprostol (n=83). The doses were repeated 4 hourly till active labour was established or up to a maximum of 4 doses. Patient factors, induction to delivery intervals, maternal side effects and fetal outcomes were noted.Results: The mean induction to active labour interval was not significantly different in the three groups (oral vs vaginal vs sublingual-7.52±4.8 vs 7.75±4.1 h vs 7.68±5.3 h; p=0.93). There was no significant difference in the induction to delivery time interval among the three misoprostol groups (oral vs vaginal vs sublingual - 10.9± 5.9 h vs 11.2±5.0 h vs 11.4±6.6 h; p= 0.88). Spontaneous vaginal delivery rate, instrumental delivery rate and lower segment ceasarean section rates were comparable among the three groups. The number of neonates with APGAR score <7 (low APGAR) at 1 minute of birth was highest in sublingual group and lowest in vaginal group which was statistically significant (oral vs vaginal vs sublingual, 16% vs 7.2% vs 20.5%; p= 0. 04). APGAR score <7 at 5 minutes was not significantly different among the three groups (oral vs vaginal vs sublingual, 4.8% vs 2.4% vs 7.2%; p=0.2). This implies that the need for immediate resuscitation was more in the sublingual group. Neonatal intensive care admission was least in the vaginal group although the difference was not statistically significant. Sublingual group had a higher rate of hyperstimulation and fetal heart rate abnormalities compared to oral and vaginal groups although these parameters did not reach statistical significance.Conclusions: Oral, vaginal and sublingual routes of administration of misoprostol are equally effective for labour induction in women with premature rupture of membranes after 34 weeks with sublingual route having slightly higher incidence of low APGAR scores at one minute for the neonate.

scholarly journals Water erosion vulnerability and sediment delivery rate in upper Iguaçu river basin – Paraná

RBRH ◽  
2016 ◽  
Vol 21 (4) ◽  
pp. 728-741 ◽  
Author(s):  
Matheus Fonseca Durães ◽  
José Alexandre Pinto Coelho Filho ◽  
Vinícius Augusto de Oliveira
Keyword(s):  
Land Use ◽  
River Basin ◽  
Water Erosion ◽  
Sustainable Land Use ◽  
Delivery Rate ◽  
Sediment Delivery ◽  
Solid Discharge ◽  
Risk Areas ◽  
Gis Environment ◽  
Iguaçu River

ABSTRACT Soil erosion is one of the most striking environmental degradation processes, which its mapping and assessment is an important tool for management activities and natural resource management in river basins, allowing managers to implement policies and sustainable land use occupation. This work aimed to apply the Revised Universal Soil Loss Equation (RUSLE) in a GIS environment in the upper Iguaçu river basin, located at Paraná State, in order to assess the vulnerability to water erosion as well as the concentration of dissolved solids in suspension to estimate the solid discharge and sediment delivery rate, allowing the identification of more susceptible areas to water erosion. The results showed that over 23.52% of the upper Iguaçu river basin presented soil losses below 2.5 t ha–1 yr–1, meaning current low potential for erosion. Regarding the solid discharge, the basin has values ranging from low to very high, also leading to high values for sediment delivery rate. The identification of risk areas associated with accelerated erosion, carried out in this study provide important information for measures associated with the management, conservation and planning of land use in the basin, which is highly relevant for predicting development of various scenarios for the state Paraná for its hydroelectric potential.

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