Gnetum gnemon L. Gnetaceae

Evaluasi Sifat Fisikokimia dan Sensoris Flakes dengan Variasi Penambahan Tepung Melinjo (Gnetum gnemon Linn.) dan Lama Pengukusan

Serambi Konstruktivis ◽

10.32672/konstruktivis.v2i1.1983 ◽

2020 ◽

Vol 2 (1) ◽

Author(s):

Irmayanti Irmayanti

Keyword(s):

Gnetum Gnemon

AbstrakTujuan dari penelitian ini untuk mengetahui pengaruh penambahan tepung melinjo terhadap karakteristik fisikokimia dan sensoris flakes, untuk mengetahui pengaruh lama pengukusan terhadap karakteristik fisiko-kimia dan sensoris flakes, untuk mengetahui pengaruh interaksi antara penambahan tepung melinjo dan lama pengukusan terhadap karakteristik fisikokimia dan sensoris flakes. Faktor penelitian yaitu menggunakan model Rancangan Acak Lengkap (RAL) faktorial yang terdiri dari 2 faktor dengan 2 kali ulangan perlakuan, sehingga diperoleh 18 satuan percobaan yaitu : Faktor I. Penambahan tepung melinjo (P) terdiri dari 3 level yaitu : P1 = 10%, P2 = 30 %, P3 = 50 % . Faktor II. Lama pengukusan (T) terdiri dari 3 level yaitu : T1 = 5 menit, T2= 10 menit, T3 = 15 menit. Parameter yang diamati adalah uji fisik (daya serap, densitas kamba, rendemen), kadar air dan uji organoleptik (warna, rasa, aroma, rasa). Flakes terbaik diperoleh dari perlakuan penambahan tepung melinjo 50 % dan lama pengukusan 15 menit (P3T3).Kata kunci : Flakes, Tepung melinjo, Jurnal SJAT, Lama pengukusan

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IDENTIFIKASI KADAR SIANIDA PADA BIJI MELINJO (Gnetum gnemon l)

Jurnal Kesehatan Bakti Tunas Husada: Jurnal Ilmu-ilmu Keperawatan, Analis Kesehatan dan Farmasi ◽

10.36465/jkbth.v17i2.283 ◽

2018 ◽

Vol 17 (2) ◽

pp. 541

Author(s):

Ummy Mardiana

Keyword(s):

Gnetum Gnemon

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The Synthesis and Characterization of Composite Electrospun Fibers of Polyvinylpyrrolidone and Shell Extract of Melinjo (Gnetum gnemon L.)

Materials Today Proceedings ◽

10.1016/j.matpr.2019.03.212 ◽

2019 ◽

Vol 13 ◽

pp. 187-192

Author(s):

Gian Prahasti ◽

Dhewa Edikresnha ◽

Yulianto Agung Rezeki ◽

Muhammad Miftahul Munir ◽

Khairurrijal Khairurrijal

Keyword(s):

Synthesis And Characterization ◽

Electrospun Fibers ◽

Gnetum Gnemon

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Potential of Gnetum gnemon L. Seed Extract Against Insulin Levels and PDX-1 Expression in Diabetes Mellitus Rats Model

10.1109/inhence52833.2021.9537215 ◽

2021 ◽

Author(s):

Rosni Rosni ◽

I Nyoman Ehrich Lister ◽

Edy Fachrial ◽

Sahna Ferdinand Ginting ◽

Wahyu Widowati ◽

...

Keyword(s):

Diabetes Mellitus ◽

Seed Extract ◽

Insulin Levels ◽

Gnetum Gnemon

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ANGIOTENSIN CONVERTING ENZYME INHIBITORY ACTIVITY OF MELINJO (GNETUM GNEMON L.) SEED EXTRACTS AND MOLECULAR DOCKING OF ITS STILBENE CONSTITUENTS

Asian Journal of Pharmaceutical and Clinical Research ◽

10.22159/ajpcr.2017.v10i3.16108 ◽

2017 ◽

Vol 10 (3) ◽

pp. 243

Author(s):

Abdul Mun'im ◽

Muhammad Ashar Munadhil ◽

Nuraini Puspitasari ◽

Azminah . ◽

Arry Yanuar

Keyword(s):

Molecular Docking ◽

Angiotensin Converting Enzyme ◽

Ethyl Acetate ◽

Inhibitory Activity ◽

Phenolic Content ◽

Ethyl Acetate Extract ◽

Total Phenolic ◽

Converting Enzyme ◽

Gnetum Gnemon ◽

Ace Inhibitory

ABSTRACTObjectives: To evaluate the angiotensin converting enzyme (ACE) inhibitory activity of melinjo (Gnetum gnemon) seed extract and to study moleculardocking of stilbene contained in melinjo seeds.Methods: Melinjo seed powders were extracted with n-hexane, dichloromethane, ethyl acetate, methanol, and water successively. The extracts wereevaluated ACE inhibitory activities using ACE kit-Wist and the phenolic content using Folin–Ciocalteu method. The extract demonstrated the highestACE inhibitory activity was subjected to liquid chromatography-mass spectrometry (LC-MS) to know its stilbene constituent. The stilbene constituentsin melinjo seed were performed molecular docking using AutoDock Vina, and ligand-receptor Interactions were processed using Ligand Scout.Results: The ethyl acetate extract demonstrated the highest ACE inhibition activity with inhibitory concentration 50% value of 9.77 × 10−8 μg/mLand the highest total phenolic content (575.9 mg gallic acid equivalent/g). Ultra-performance LC-MS analysis of ethyl acetate extract has detected theexistency of resveratrol, gnetin C, ε-viniferin, and gnemonoside A/B. These compounds displayed similar physiochemical properties to lisinopril (ACEinhibitor), as in silico molecular docking studies demonstrated that they fit into the lisinopril receptors.Conclusion: In vitro analysis ethyl acetate extract from melinjo seeds demonstrated the highest ACE inhibitory activity. Molecular docking analysisindicated that resveratrol dimers, gnetin C and gnemonoside A can be considered ACE inhibitor.Keywords: Angiotensin converting enzyme inhibitor, Gnetum gnemon, Melinjo, Total phenolic, Antihypertension, Molecular docking.

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