Integrated Network-Based Computational Analysis for Drug Development

2021 ◽  
pp. 169-183
Author(s):  
Mijin Kwon ◽  
Soorin Yim ◽  
Gwangmin Kim ◽  
Doheon Lee
Keyword(s):  
Drug Development ◽  
Computational Analysis ◽  
Integrated Network

Spatial Representations as an Emergent Feature of Perceptual Processing

2010 ◽  
Vol 24 (3) ◽  
pp. 161-172 ◽  
Author(s):  
Edmund Wascher ◽  
C. Beste
Keyword(s):  
Common Ground ◽  
Event Related Potentials ◽  
Vertical Axis ◽  
Relevant Information ◽  
Sources Of Information ◽  
Integrated Network ◽  
Perceptual Maps ◽  
Emergent Feature ◽  
Related Potentials ◽  
Selection Of

Spatial selection of relevant information has been proposed to reflect an emergent feature of stimulus processing within an integrated network of perceptual areas. Stimulus-based and intention-based sources of information might converge in a common stage when spatial maps are generated. This approach appears to be inconsistent with the assumption of distinct mechanisms for stimulus-driven and top-down controlled attention. In two experiments, the common ground of stimulus-driven and intention-based attention was tested by means of event-related potentials (ERPs) in the human EEG. In both experiments, the processing of a single transient was compared to the selection of a physically comparable stimulus among distractors. While single transients evoked a spatially sensitive N1, the extraction of relevant information out of a more complex display was reflected in an N2pc. The high similarity of the spatial portion of these two components (Experiment 1), and the replication of this finding for the vertical axis (Experiment 2) indicate that these two ERP components might both reflect the spatial representation of relevant information as derived from the organization of perceptual maps, just at different points in time.

A update of botanical drug development in the United States: Status of applications

Planta Medica ◽  
2015 ◽  
Vol 81 (11) ◽  
Author(s):  
KM Wu ◽  
C Wu ◽  
J Dou ◽  
H Ghantous ◽  
S Lee ◽  
...  
Keyword(s):  
United States ◽  
Drug Development ◽  
The United States ◽  
Botanical Drug

Comparative Pharmacology of Site Directed Antithrombin Agents. Implication in Drug Development

1995 ◽  
Vol 74 (01) ◽  
pp. 473-481 ◽  
Author(s):  
Demetra Callas ◽  
Jawad Fareed
Keyword(s):  
Drug Development
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