:
Thiophenes are one among the abundantly found heterocyclic ring systems in many biologically active
compounds. Moreover various substituted thiophenes exert numerous pharmacological actions on account of their isosteric
resemblance with compounds of natural origin thus rendering them with diverse actions like antibacterial, antifungal,
antiviral, anti-inflammatory, analgesic, antiallergic, hypotensives etc.. In this review we specifically explore the
chemotherapeutic potential of variety of structures consisting of thiophene scaffolds as prospective anticancer agents.