Cytotoxic Chemotherapy for Advanced Bladder and Upper Tract Cancer

2021 ◽  
pp. 289-304
Author(s):  
Rosa Nadal ◽  
Joaquim Bellmunt
Keyword(s):  
Cytotoxic Chemotherapy ◽  
Upper Tract ◽  
Tract Cancer

scholarly journals MP24-04 DIAGNOSTIC TEST PERFORMANCE OF ULTRASOUND AND CYTOLOGY IN UPPER TRACT CANCER– RESULTS FROM THE IDENTIFY STUDY

2020 ◽  
Vol 203 ◽  
pp. e348
Author(s):  
Miles Mannas* ◽  
Sinan Khadhouri ◽  
Kevin M Gallagher ◽  
Kenneth R Mackenzie ◽  
Taimur T Shah ◽  
...  
Keyword(s):  
Diagnostic Test ◽  
Test Performance ◽  
Upper Tract ◽  
Tract Cancer ◽  
Diagnostic Test Performance

scholarly journals Diagnostic utility of axial imaging in the evaluation of hematuria: A systematic review and critical appraisal of the literature

2020 ◽  
Vol 15 (2) ◽  
Author(s):  
Christopher J.D. Wallis ◽  
Rashid K. Sayyid ◽  
Roni Manyevitch ◽  
Nathan Perlis ◽  
Vinata B. Lokeshwar ◽  
...  
Keyword(s):  
Systematic Review ◽  
Urinary Tract ◽  
Meta Analysis ◽  
Sampling Bias ◽  
Upper Urinary Tract ◽  
Risk Of Bias ◽  
Microscopic Hematuria ◽  
Gross Hematuria ◽  
Upper Tract ◽  
Tract Cancer

Introduction: Increasing severity of hematuria is instinctively associated with higher likelihood of urological malignancy. However, the robustness of the evidentiary base for this assertion is unclear, particularly as it relates to the likelihood of upper urinary tract pathology. Thus, the value of axial imaging in the diagnostic workup of hematuria is unclear due to differences in the underlying patient populations, raising concern for sampling bias. We performed a systematic review to characterize the literature and association between severity of hematuria and likelihood of upper urinary tract cancer based on axial imaging. Methods: MEDLINE, EMBASE, and Cochrane were systematically searched for all studies reporting on adult patients presenting with hematuria. We used Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) for reporting of this systematic review and meta-analysis and the Newcastle-Ottawa Scale for risk of bias assessment. Degree of hematuria was classified as “microscopic,” “gross,” or “unspecified.” Three urologic malignancies (bladder, upper tract urothelial, and renal cancer) were considered both individually and in aggregate. Random effects model with pairwise comparisons was employed to arrive at the axial imaging diagnostic yields. Results: Twenty-nine studies were included, of which six (20.7%) reported on patients with gross hematuria only, four (13.8%) reported on patients with microscopic hematuria only, seven (24.1%) included both, and 12 (41.4%) did not define or specify the severity of hematuria. Of 29 studies, two (6.9%) were at high-risk of bias, 21 (72.4%) at intermediate-risk, and six (20.7%) at low-risk of bias using the Newcastle-Ottawa criteria. Based on axial imaging, rates of diagnoses of renal, upper tract urothelial, and bladder cancers differed with differing severity of hematuria. Notably, rates of renal and upper tract urothelial carcinoma were higher in studies of patients with unspecified hematuria severity (3.6% and 10.4%, respectively) than among patients with gross hematuria (1.5% and 1.3%, respectively). When all urological malignancies were pooled, patients with unspecified hematuria were diagnosed more frequently (19.5%) compared to those with gross (15.3%) and microscopic hematuria (4.5%, difference = 1.51%; 99% confidence interval 3.6–26.5%). Conclusions: Lack of granularity in the available literature, particularly with regards to patients with unspecified hematuria severity, limits the generalizability of these results and highlights the need for future studies that provide sufficient baseline information allowing for firmer conclusions to be drawn.

Role of Chemotherapy and Immunotherapy for Urinary Upper Tract Cancer

2010 ◽  
Vol 9 (3) ◽  
pp. 446-449 ◽  
Author(s):  
Christian Pfister
Keyword(s):  
Upper Tract ◽  
Tract Cancer

scholarly journals Diagnostic test performance of ultrasound and cytology in upper tract cancer – results from the IDENTIFY study

2020 ◽  
Vol 19 ◽  
pp. e2181-e2182
Author(s):  
S. Khadhouri ◽  
K.M. Gallagher ◽  
T. Shah T. ◽  
K.R. Mackenzie ◽  
S. Moore ◽  
...  
Keyword(s):  
Diagnostic Test ◽  
Test Performance ◽  
Upper Tract ◽  
Tract Cancer ◽  
Diagnostic Test Performance

405: Previous History of Bladder Cancer is an Independent Prognostic Factor for Upper Tract Transitional Cell Carcinoma

2007 ◽  
Vol 177 (4S) ◽  
pp. 135-135
Author(s):  
Eiji Kikuchi ◽  
Akira Miyajima ◽  
Ken Nakagawa ◽  
Mototsugu Oya ◽  
Takashi Ohigashi ◽  
...  
Keyword(s):  
Bladder Cancer ◽  
Prognostic Factor ◽  
Transitional Cell Carcinoma ◽  
Cell Carcinoma ◽  
Transitional Cell ◽  
Previous History ◽  
Independent Prognostic Factor ◽  
Upper Tract ◽  
History Of

1508: Histopathologic Examination of Ureteroscopic Biopsy in Upper Tract Disease is Both Possible and Predictive of Final Pathology

2004 ◽  
Vol 171 (4S) ◽  
pp. 397-397
Author(s):  
Louis J. Giorgi ◽  
Michael Perrotti ◽  
Jerry H. Broman ◽  
Khurram Mehtabdin ◽  
Brian Finn ◽  
...  
Keyword(s):  
Histopathologic Examination ◽  
Final Pathology ◽  
Upper Tract ◽  
Tract Disease

1763: Stage Migration of upper Tract Transitional Cell Carcinoma: An Argument for the Continued Role of Endourologic Diagnosis and Treatment

2004 ◽  
Vol 171 (4S) ◽  
pp. 466-466
Author(s):  
Stephen A. Boorjian ◽  
Casey K. Ng ◽  
Ravi Munver ◽  
R. Ernest Sosa ◽  
E. Darracott Vaughan ◽  
...  
Keyword(s):  
Transitional Cell Carcinoma ◽  
Cell Carcinoma ◽  
Transitional Cell ◽  
Diagnosis And Treatment ◽  
Stage Migration ◽  
Upper Tract
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