Treatment Approach to Carcinomas of Unknown Primary

2022 ◽  
pp. 433-441
Author(s):  
Sinan Unal ◽  
Hüseyin Salih Semiz ◽  
Ilhan Oztop
Keyword(s):  
Treatment Approach ◽  
Unknown Primary

Five-year outcomes of an oropharynx-directed treatment approach for unknown primary of the head and neck

Oral Oncology ◽  
2017 ◽  
Vol 70 ◽  
pp. 14-22 ◽  
Author(s):  
Kenneth Shung Hu ◽  
Waleed Fouad Mourad ◽  
Mauricio E. Gamez ◽  
Wilson Lin ◽  
Adam Saul Jacobson ◽  
...  
Keyword(s):  
Head And Neck ◽  
Treatment Approach ◽  
Unknown Primary

scholarly journals Cancer of unknown primary origin: a case report

2013 ◽  
Vol 7 (1) ◽  
pp. 27-34
Author(s):  
Elisa De Carlo ◽  
Ciro Rossetto ◽  
Gianpiero Fasola
Keyword(s):  
Treatment Approach ◽  
Histopathological Examination ◽  
Imaging Techniques ◽  
Primary Tumour ◽  
Molecular Diagnostic ◽  
Diagnostic Tools ◽  
Unknown Primary ◽  
Apparent Absence ◽  
Primary Origin ◽  
Unknown Primary Origin

Carcinoma of unknown primary origin (CUP) accounts for 2-10% of all malignancies. The apparent absence of the primary tumour, the development of early, uncommon systemic metastases and the resistance to therapy and poor prognosis are hallmarks of this heterogeneous clinical entity and are a challenge for physicians. The diagnostic workup of patients with CUP includes a large amount of histopathological examination, as well as the use of imaging techniques that often fail to identify the primary tumour. Therefore, the optimal workup and treatment for these patients remains to be determined. Molecular diagnostic tools, such as DNA microarray analysis, could help in the search for "lost" CUP origin and guide the further treatment approach. We report the case of a 66-year-old man, with mediastinal lymph nodes metastasis of carcinoma and neurological syndrome with diplopia and balance disorders, in which many exams have been performed without finding the primary tumour.

Productivity of Emerging Word Combinations in Toddlers With Specific Expressive Language Impairment

1997 ◽  
Vol 6 (4) ◽  
pp. 34-47 ◽  
Author(s):  
Steven H. Long ◽  
Lesley B. Olswang ◽  
Julianne Brian ◽  
Philip S. Dale
Keyword(s):  
Data Collection ◽  
Young Children ◽  
Language Impairment ◽  
Treatment Approach ◽  
Expressive Language ◽  
Semantic Consistency ◽  
Session Analysis

This study investigated whether young children with specific expressive language impairment (SELI) learn to combine words according to general positional rules or specific, grammatic relation rules. The language of 20 children with SELI (4 females, 16 males, mean age of 33 months, mean MLU of 1.34) was sampled weekly for 9 weeks. Sixteen of these children also received treatment for two-word combinations (agent+action or possessor+possession). Two different metrics were used to determine the productivity of combinatorial utterances. One metric assessed productivity based on positional consistency alone; another assessed productivity based on positional and semantic consistency. Data were analyzed session-by-session as well as cumulatively. The results suggest that these children learned to combine words according to grammatic relation rules. Results of the session-by-session analysis were less informative than those of the cumulative analysis. For children with SELI ready to make the transition to multiword utterances, these findings support a cumulative method of data collection and a treatment approach that targets specific grammatic relation rules rather than general word combinations.

Abstract #817: Pituitary Metastasis with an Unknown Primary

2015 ◽  
Vol 21 ◽  
pp. 156
Author(s):  
Halis Akturk ◽  
Kaniksha Desai ◽  
Ana Maria Chindris
Keyword(s):  
Unknown Primary ◽  
Pituitary Metastasis
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