Emergent Anisotropy and Flow Alignment in Viscous Rock

Author(s):  
H. B. MÜHlhaus ◽  
H. B. Moresi ◽  
M. CADA
Keyword(s):  
2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Nae-Chyun Chen ◽  
Brad Solomon ◽  
Taher Mun ◽  
Sheila Iyer ◽  
Ben Langmead

AbstractMost sequencing data analyses start by aligning sequencing reads to a linear reference genome, but failure to account for genetic variation leads to reference bias and confounding of results downstream. Other approaches replace the linear reference with structures like graphs that can include genetic variation, incurring major computational overhead. We propose the reference flow alignment method that uses multiple population reference genomes to improve alignment accuracy and reduce reference bias. Compared to the graph aligner vg, reference flow achieves a similar level of accuracy and bias avoidance but with 14% of the memory footprint and 5.5 times the speed.


2019 ◽  
Author(s):  
Pezhman Mohammadi ◽  
A. Sesilja Aranko ◽  
Christopher P. Landowski ◽  
Olli Ikkala ◽  
Kristaps Jaudzems ◽  
...  

Silk and cellulose are biopolymers that show a high potential as future sustainable materials.They also have complementary properties, suitable for combination in composite materials where cellulose would form the reinforcing component and silk the tough matrix. Therein, a major challenge concerns balancing structure and properties in the assembly process. We used recombinant proteins with triblock architecture combining structurally modified spider silk with terminal cellulose affinity modules. Flow-alignment of cellulose nanofibrils and triblock protein allowed a continuous fiber production.The protein assembly involved phase separation into concentrated coacervates, with subsequent conformational switching from disordered structures to beta sheets. This gave the matrix a tough adhesiveness, forming a new composite material with high strength and stiffness combined with increased toughness. We show that versatile design possibilities in protein engineering enable new fully biological materials, and emphasize the key role of controlled assembly at multiple length scales for realization.<br>


Author(s):  
Peter Berntsen ◽  
Connie Darmanin ◽  
Eugeniu Balaur ◽  
Leonie Flueckiger ◽  
Alex Kozlov ◽  
...  

2011 ◽  
Vol 186 (1) ◽  
pp. 175-192 ◽  
Author(s):  
Christopher C. Finlay ◽  
Hagay Amit

1994 ◽  
Vol 27 (5) ◽  
pp. 1177-1186 ◽  
Author(s):  
Rangaramanujam M. Kannan ◽  
Julia A. Kornfield

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