The Parasympathetic Nervous System and Heart Failure: Pathophysiology and Potential Therapeutic Modalities for Heart Failure

2015 ◽  
pp. 107-128
Author(s):  
Brian Olshansky ◽  
Renee M. Sullivan ◽  
Wilson S. Colucci ◽  
Hani N. Sabbah
Keyword(s):  
Heart Failure ◽  
Nervous System ◽  
Parasympathetic Nervous System ◽  
Therapeutic Modalities

scholarly journals Parasympathetic Nervous System and Heart Failure

Circulation ◽  
2008 ◽  
Vol 118 (8) ◽  
pp. 863-871 ◽  
Author(s):  
Brian Olshansky ◽  
Hani N. Sabbah ◽  
Paul J. Hauptman ◽  
Wilson S. Colucci
Keyword(s):  
Heart Failure ◽  
Nervous System ◽  
Parasympathetic Nervous System

The Beauty and the Beast: Aspects of the Autonomic Nervous System

Physiology ◽  
2000 ◽  
Vol 15 (3) ◽  
pp. 125-129 ◽  
Author(s):  
Roberto Corti ◽  
Christian Binggeli ◽  
Isabella Sudano ◽  
Lukas E. Spieker ◽  
René R. Wenzel ◽  
...  
Keyword(s):  
Heart Failure ◽  
Congestive Heart Failure ◽  
Nervous System ◽  
Sympathetic Nerve Activity ◽  
Vasoactive Drugs ◽  
Nerve Activity ◽  
Beauty And The Beast ◽  
Coronary Syndromes ◽  
Sympathetic Nervous ◽  
Selection Of

Sympathetic nerve activity is altered and is a prognostic factor for many cardiovascular diseases such as hypertension, coronary syndromes, and congestive heart failure. Therefore, the selection of vasoactive drugs for the treatment of these diseases should also take into consideration their effects on the sympathetic nervous system.

scholarly journals Daily inhalation of hydrogen gas has a blood pressure-lowering effect in a rat model of hypertension

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Kazuhisa Sugai ◽  
Tomoyoshi Tamura ◽  
Motoaki Sano ◽  
Shizuka Uemura ◽  
Masahiko Fujisawa ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Nervous System ◽  
Parasympathetic Nervous System ◽  
Pressure Control ◽  
Hydrogen Gas ◽  
Blood Pressure Lowering ◽  
Blood Pressure Lowering Effect ◽  
Night Time ◽  
Lowering Effect ◽  
Pressure Lowering

AbstractA recent clinical study demonstrated that haemodialysis with a dialysate containing hydrogen (H2) improves blood pressure control in end-stage kidney disease. Herein, we examined whether H2 has a salutary effect on hypertension in animal models. We subjected 5/6 nephrectomised rats to inhalation of either H2 (1.3% H2 + 21% O2 + 77.7% N2) or control (21% O2 + 79% N2) gas mixture for 1 h per day. H2 significantly suppressed increases in blood pressure after 5/6 nephrectomy. The anti-hypertensive effect of H2 was also confirmed in rats in a stable hypertensive state 3 weeks after nephrectomy. To examine the detailed effects of H2 on hypertension, we used an implanted telemetry system to continuously monitor blood pressure. H2 exerted an anti-hypertensive effect not only during daytime rest, but also during night-time activities. Spectral analysis of blood pressure variability revealed that H2 improved autonomic imbalance, namely by suppressing the overly active sympathetic nervous system and augmenting parasympathetic nervous system activity; these effects co-occurred with the blood pressure-lowering effect. In conclusion, 1-h daily exposure to H2 exerts an anti-hypertensive effect in an animal model of hypertension.

scholarly journals Central Nervous System Changes in Pediatric Heart Failure: A Volumetric Study

2010 ◽  
Vol 31 (7) ◽  
pp. 969-976 ◽  
Author(s):  
Jondavid Menteer ◽  
Paul M. Macey ◽  
Mary A. Woo ◽  
Ashok Panigrahy ◽  
Ronald M. Harper
Keyword(s):  
Heart Failure ◽  
Central Nervous System ◽  
Nervous System ◽  
System Changes ◽  
Volumetric Study ◽  
Pediatric Heart Failure
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