Case 17: Tibial Atrophic Nonunion with Deformity and 4 cm LLD

2015 ◽  
pp. 123-127
Author(s):  
Mahmoud A. El-Rosasy
Keyword(s):  
Atrophic Nonunion

Role of Autologous Bone Graft in the Surgical Treatment of Atrophic Nonunion of Midshaft Clavicular Fractures

Orthopedics ◽  
2012 ◽  
Author(s):  
Hui-Kuang Huang ◽  
Chao-Ching Chiang ◽  
Yu-Ping Su ◽  
Chi-Kuang Feng ◽  
Fang-Yao Chiu ◽  
...  
Keyword(s):  
Surgical Treatment ◽  
Bone Graft ◽  
Autologous Bone Graft ◽  
Autologous Bone ◽  
Atrophic Nonunion

scholarly journals Biomarkers of inflammation and innate immunity in atrophic nonunion fracture

2016 ◽  
Vol 14 (1) ◽  
Author(s):  
Dominique de Seny ◽  
Gaël Cobraiville ◽  
Pierre Leprince ◽  
Marianne Fillet ◽  
Charlotte Collin ◽  
...  
Keyword(s):  
Innate Immunity ◽  
Atrophic Nonunion

scholarly journals Increased serum OPG in atrophic nonunion shaft fractures

2009 ◽  
Vol 10 (2) ◽  
pp. 55-58 ◽  
Author(s):  
Daniele Marchelli ◽  
Luca P. Piodi ◽  
Costantino Corradini ◽  
Luca Parravicini ◽  
Cesare Verdoia ◽  
...  
Keyword(s):  
Shaft Fractures ◽  
Atrophic Nonunion

scholarly journals Mesenchymal stem cell implantation in atrophic nonunion of the long bones

2016 ◽  
Vol 5 (7) ◽  
pp. 287-293 ◽  
Author(s):  
H.D. Ismail ◽  
P. Phedy ◽  
E. Kholinne ◽  
Y. P. Djaja ◽  
Y. Kusnadi ◽  
...  
Keyword(s):  
Stem Cell ◽  
Mesenchymal Stem Cell ◽  
Long Bones ◽  
Atrophic Nonunion ◽  
Cell Implantation

Clinical Efficacy of Bone Reconstruction Surgery with Frozen Cortical Bone Allografts for Nonunion of Radial and Ulnar Fractures in Toy Breed Dogs

2018 ◽  
Vol 31 (03) ◽  
pp. 159-169
Author(s):  
Yukari Nagahiro ◽  
Daichi Katori ◽  
Norihiro Muroi ◽  
Hiroyuki Akagi ◽  
Nobuo Kanno ◽  
...  
Keyword(s):  
Cortical Bone ◽  
Bone Remodelling ◽  
Weight Bearing ◽  
Healing Process ◽  
Bone Reconstruction ◽  
Bone Allografts ◽  
Bone Remodelling Process ◽  
Large Bone ◽  
Atrophic Nonunion ◽  
Large Bone Defects

Objective To evaluate the effectiveness of frozen cortical bone allografts (FCBA) in the treatment of severe radial and ulnar atrophic nonunion fractures. Animals Toy breed dogs with nonunion of radial and ulnar fractures (n = 15). Methods Severe atrophic nonunion fractures were treated with FCBA (eight infected and seven non-infected fractures). Radiographs obtained immediately after surgery, and 1, 2, 3, 6 and 12 months later were evaluated and scored for the periosteal reaction at the bone regeneration sites, the healing process in the bone connection areas at both the proximal and distal sites, and the bone remodelling process within the allografts. Results Improvements in the fracture-healing process and weight-bearing function were observed in all cases. Radiographic scores at the bone connection areas and within the allograft improved significantly over time (p < 0.05). There were not any significant differences in radiographic scores between the infected and non-infected groups. Clinical Significance Bone reconstruction with FCBA is effective in the treatment of radial and ulnar nonunion fractures associated with large bone defects, regardless of the infection status of the surgical site.

Feasibility of Percutaneous Gene Transfer to an Atrophic Nonunion in a Rabbit

2004 ◽  
Vol 425 ◽  
pp. 237-243 ◽  
Author(s):  
Christian Lattermann ◽  
Axel W Baltzer ◽  
Boris A Zelle ◽  
Janey D Whalen ◽  
Christopher Niyibizi ◽  
...  
Keyword(s):  
Gene Transfer ◽  
Atrophic Nonunion

scholarly journals Do Systemic Factors Influence the Fate of Nonunions to Become Atrophic? A Retrospective Analysis of 162 Cases

2019 ◽  
Vol 2019 ◽  
pp. 1-12 ◽  
Author(s):  
Markus Rupp ◽  
Stefanie Kern ◽  
Thaqif El Khassawna ◽  
Abdullah Ismat ◽  
Deeksha Malhan ◽  
...  
Keyword(s):  
Mechanical Stability ◽  
Scientific Evidence ◽  
Fibrous Tissue ◽  
Patient Characteristics ◽  
The Elderly ◽  
Long Bone ◽  
Osteogenic Potential ◽  
Accompanying Injuries ◽  
Systemic Factors ◽  
Atrophic Nonunion

Introduction. Nonunions are a challenge for orthopedic surgeons. In hypertrophic nonunions, improvement of mechanical stability usually is the satisfactory treatment, whereas in atrophic nonunions improvement of the biological environment is most important. However, scientific evidence revealed that “avital” nonunions are not avascular and fibrous tissue contains cells with osteogenic potential. To find out if systemic factors suppress this intrinsic potential in atrophic nonunions, this study compares characteristics of hypertrophic with atrophic nonunion patients. Methods. We analyzed medical records of 162 surgically treated patients suffering from aseptic long bone nonunions. Atrophic and hypertrophic nonunions were distinguished by absence or presence of callus and calcification in the fracture gap. Mechanical implant loosening and patient characteristics such as age, gender, and body mass index were assessed. Fracture classification according to AO/OTA, open and closed fractures, and osteosynthesis were recorded. In addition, comorbidities and allergies between both groups were compared. Results. A higher number of hypertrophic nonunion patients were male with often allergies. Hypertrophic nonunion occurred more often after intramedullary nailing compared to atrophic nonunions. Atrophic nonunion patients being nonallergic were significantly older than nonallergic patients suffering from hypertrophic nonunions. In both atrophic and hypertrophic nonunion patients, age was lower in patients with accompanying injuries compared with age of patients with isolated fractures. Conclusion. Systemic factors influence development of nonunion types. In nonallergic patients, atrophic nonunions occur more often in the elderly. This manuscript is a first step to identify different factors which might influence the nature of nonunion. To enable nonunion treatment which is tailored to individual patient characteristics, further prospective studies with more sophisticated research methods are necessary.

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