Minimally Invasive Resection of Colorectal Liver Metastases

2017 ◽  
pp. 95-108
Author(s):  
Lee M. Ocuin ◽  
Allan Tsung
Keyword(s):  
Minimally Invasive ◽  
Liver Metastases ◽  
Colorectal Liver Metastases

scholarly journals Technical feasibility and short-term outcomes of laparoscopic isolated caudate lobe resection: an IgoMILS (Italian Group of Minimally Invasive Liver Surgery) registry-based study

2021 ◽  
Author(s):  
Andrea Ruzzenente ◽  
◽  
Andrea Ciangherotti ◽  
Luca Aldrighetti ◽  
Giuseppe Maria Ettorre ◽  
...  
Keyword(s):  
Minimally Invasive ◽  
Liver Metastases ◽  
Hospital Stay ◽  
Complication Rate ◽  
Liver Surgery ◽  
Colorectal Liver Metastases ◽  
Caudate Lobe ◽  
Open Group ◽  
Perioperative Outcomes ◽  
Minimally Invasive Liver Surgery

Abstract Background Although isolated caudate lobe (CL) liver resection is not a contraindication for minimally invasive liver surgery (MILS), feasibility and safety of the procedure are still poorly investigated. To address this gap, we evaluate data on the Italian prospective maintained database on laparoscopic liver surgery (IgoMILS) and compare outcomes between MILS and open group. Methods Perioperative data of patients with malignancies, as colorectal liver metastases (CRLM), hepatocellular carcinoma (HCC), intrahepatic cholangiocarcinoma (ICC), non-colorectal liver metastases (NCRLM) and benign liver disease, were retrospectively analyzed. A propensity score matching (PSM) analysis was performed to balance the potential selection bias for MILS and open group. Results A total of 224 patients were included in the study, 47 and 177 patients underwent MILS and open isolated CL resection, respectively. The overall complication rate was comparable between the two groups; however, severe complication rate (Dindo–Clavien grade ≥ 3) was lower in the MILS group (0% versus 6.8%, P = ns). In-hospital mortality was 0% in both groups and mean hospital stay was significantly shorter in the MILS group (P = 0.01). After selection of 42 MILS and 43 open CL resections by PSM analysis, intraoperative and postoperative outcomes remained similar except for the hospital stay which was not significantly shorter in MILS group. Conclusions This multi-institutional cohort study shows that MILS CL resection is feasible and safe. The surgical procedure can be technically demanding compared to open resection, whereas good perioperative outcomes can be achieved in highly selected patients.

Impact of Immune Response in Short-term and Long-term Outcomes After Minimally Invasive Surgery for Colorectal Liver Metastases

2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Victor Lopez-Lopez ◽  
Alvaro Gómez Ruiz ◽  
Pablo Pelegrin ◽  
Beatriz Abellán ◽  
Asunción Lopez-Conesa ◽  
...  
Keyword(s):  
Immune Response ◽  
Minimally Invasive Surgery ◽  
Minimally Invasive ◽  
Liver Metastases ◽  
Invasive Surgery ◽  
Colorectal Liver Metastases ◽  
Long Term Outcomes ◽  
Short Term

scholarly journals Minimally Invasive Evaluation and Treatment of Colorectal Liver Metastases

2011 ◽  
Vol 2011 ◽  
pp. 1-12
Author(s):  
Anton L. Gueorguiev ◽  
Richard Mackey ◽  
Gopal C. Kowdley ◽  
Jesus Esquivel ◽  
Steven C. Cunningham
Keyword(s):  
Minimally Invasive ◽  
Liver Metastases ◽  
Colorectal Liver Metastases ◽  
Randomized Trials ◽  
Ablation Therapy ◽  
Surgeon Training ◽  
Laparoscopic Techniques ◽  
Major Hepatectomies ◽  
Invasive Techniques ◽  
Invasive Evaluation

Minimally invasive techniques used in the evaluation and treatment of colorectal liver metastases (CRLMs) include ultrasonography (US), computed tomography, magnetic resonance imaging, percutaneous and operative ablation therapy, standard laparoscopic techniques, robotic techniques, and experimental techniques of natural orifice endoscopic surgery. Laparoscopic techniques range from simple staging laparoscopy with or without laparoscopic intraoperative US, through intermediate techniques including simple liver resections (LRs), to advanced techniques such as major hepatectomies. Hereins, we review minimally invasive evaluation and treatment of CRLM, focusing on a comparison of open LR (OLR) and minimally invasive LR (MILR). Although there are no randomized trials comparing OLR and MILR, nonrandomized data suggest that MILR compares favorably with OLR regarding morbidity, mortality, LOS, and cost, although significant selection bias exists. The future of MILR will likely include expanding criteria for resectability of CRLM and should include both a patient registry and a formalized process for surgeon training and credentialing.

scholarly journals Real-time surgical margin assessment using ICG-fluorescence during minimally invasive resections of colorectal liver metastases

HPB ◽  
2020 ◽  
Vol 22 ◽  
pp. S246
Author(s):  
F. Achterberg ◽  
B. Sibinga Mulder ◽  
B. Bonsing ◽  
H. Hartgrink ◽  
R. Meijer ◽  
...  
Keyword(s):  
Minimally Invasive ◽  
Liver Metastases ◽  
Real Time ◽  
Colorectal Liver Metastases ◽  
Surgical Margin ◽  
Margin Assessment

Open versus minimally invasive liver surgery for colorectal liver metastases (LapOpHuva): a prospective randomized controlled trial

2019 ◽  
Vol 33 (12) ◽  
pp. 3926-3936 ◽  
Author(s):  
Ricardo Robles-Campos ◽  
Víctor Lopez-Lopez ◽  
Roberto Brusadin ◽  
Asunción Lopez-Conesa ◽  
Pedro José Gil-Vazquez ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Minimally Invasive ◽  
Liver Metastases ◽  
Liver Surgery ◽  
Colorectal Liver Metastases ◽  
Controlled Trial ◽  
Minimally Invasive Liver Surgery ◽  
Randomized Controlled ◽  
Prospective Randomized Controlled Trial ◽  
Open Versus

Outcomes of robotic liver resections for colorectal liver metastases. A multi-institutional analysis of minimally invasive ultrasound-guided robotic surgery

2019 ◽  
Vol 28 ◽  
pp. 14-18 ◽  
Author(s):  
Francesco Guerra ◽  
Simone Guadagni ◽  
Benedetta Pesi ◽  
Niccolò Furbetta ◽  
Gregorio Di Franco ◽  
...  
Keyword(s):  
Robotic Surgery ◽  
Minimally Invasive ◽  
Liver Metastases ◽  
Colorectal Liver Metastases ◽  
Institutional Analysis ◽  
Ultrasound Guided ◽  
Liver Resections

scholarly journals Open Resection Compared to Mini-Invasive in Colorectal Cancer and Liver Metastases: A Meta-Analysis

2021 ◽  
Vol 8 ◽  
Author(s):  
Jie Gong ◽  
Fengwei Gao ◽  
Qingyun Xie ◽  
Xin Zhao ◽  
Zehua Lei
Keyword(s):  
Colorectal Cancer ◽  
Minimally Invasive Surgery ◽  
Minimally Invasive ◽  
Liver Metastases ◽  
Invasive Surgery ◽  
Open Surgery ◽  
Colorectal Liver Metastases ◽  
Disease Free Survival ◽  
Simultaneous Resection ◽  
Synchronous Colorectal Liver Metastases

Background: We performed a meta-analysis to evaluate the outcomes of minimally invasive surgery and open surgery in the simultaneous resection of colorectal cancer and synchronous colorectal liver metastases.Methods: A systematic literature search up to April 2021 was done and 13 studies included 1,181 subjects with colorectal cancer and synchronous colorectal liver metastases at the start of the study; 425 of them were using minimally invasive surgery and 756 were open surgery. They were reporting relationships between the outcomes of minimally invasive surgery and open surgery in the simultaneous resection of colorectal cancer and synchronous colorectal liver metastases. We calculated the odds ratio (OR) or the mean difference (MD) with 95% CIs to assess the outcomes of minimally invasive surgery and open surgery in the simultaneous resection of colorectal cancer and synchronous colorectal liver metastases using the dichotomous or continuous method with a random or fixed-effect model.Results: Minimally invasive surgery in subjects with colorectal cancer and synchronous colorectal liver metastases was significantly related to longer operation time (MD, 35.61; 95% CI, 7.36–63.87, p = 0.01), less blood loss (MD, −151.62; 95% CI, −228.84 to −74.40, p < 0.001), less blood transfusion needs (OR, 0.61; 95% CI, 0.42–0.89, p = 0.01), shorter length of hospital stay (MD, −3.26; 95% CI, −3.67 to −2.86, p < 0.001), lower overall complications (OR, 0.59; 95% CI, 0.45–0.79, p < 0.001), higher overall survival (OR, 1.66; 95% CI, 1.21–2.29, p = 0.002), and higher disease-free survival (OR, 1.49; 95% CI, 1.13–1.97, p = 0.005) compared to open surgery.Conclusions: Minimally invasive surgery in subjects with colorectal cancer and synchronous colorectal liver metastases may have less blood loss, less blood transfusion needs, shorter length of hospital stay, lower overall complications, higher overall survival, and higher disease-free survival with longer operation time compared with the open surgery. Furthers studies are required to validate these findings.

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