Human Papillomavirus Research in Latin America

2017 ◽  
pp. 389-409
Author(s):  
María Alejandra Picconi ◽  
Luisa Lina Villa
Keyword(s):  
Latin America ◽  
Human Papillomavirus

scholarly journals An alert to Latin America: Current human papillomavirus vaccination trends highlight key barriers to successful implementation

Cancer ◽  
2017 ◽  
Vol 123 (12) ◽  
pp. 2193-2199 ◽  
Author(s):  
Angelica Nogueira-Rodrigues ◽  
Alexandra Bukowski ◽  
Eduardo Paulino ◽  
Jessica St. Louis ◽  
Adriana Barrichello ◽  
...  
Keyword(s):  
Latin America ◽  
Human Papillomavirus ◽  
Successful Implementation ◽  
Human Papillomavirus Vaccination

scholarly journals Whole-Genome Sequencing of an Unusual Human Papillomavirus (HPV71) from Latin America (Brazil)

2020 ◽  
Vol 9 (24) ◽  
Author(s):  
Edivaldo Costa Sousa Junior ◽  
Allan Kaio Silva ◽  
Laryssa Danielle da Silva Reis ◽  
Lana Patricia da Silva Fonseca ◽  
Fabiano Reis da Silva ◽  
...  
Keyword(s):  
Latin America ◽  
Human Papillomavirus ◽  
Whole Genome Sequencing ◽  
Genome Sequencing ◽  
Complete Genome ◽  
Whole Genome ◽  
Complete Genome Sequencing

ABSTRACT We report the complete genome sequencing of human papillomavirus 71 from Latin America (Brazil).

scholarly journals Multicentric study of cervical cancer screening with human papillomavirus testing and assessment of triage methods in Latin America: the ESTAMPA screening study protocol

BMJ Open ◽  
2020 ◽  
Vol 10 (5) ◽  
pp. e035796
Author(s):  
Maribel Almonte ◽  
Raúl Murillo ◽  
Gloria Inés Sánchez ◽  
Paula González ◽  
Annabelle Ferrera ◽  
...  
Keyword(s):  
Latin America ◽  
Human Papillomavirus ◽  
Study Protocol ◽  
Low Income ◽  
International Agency ◽  
Hpv Testing ◽  
Middle Income ◽  
Multicentric Study ◽  
Predictive Values ◽  
Hpv Test

IntroductionHuman papillomavirus (HPV) testing is replacing cytology in primary screening. Its limited specificity demands using a second (triage) test to better identify women at high-risk of cervical disease. Cytology represents the immediate triage but its low sensitivity might hamper HPV testing sensitivity, particularly in low-income and middle-income countries (LMICs), where cytology performance has been suboptimal. The ESTAMPA (EStudio multicéntrico de TAMizaje y triaje de cáncer de cuello uterino con pruebas del virus del PApiloma humano; Spanish acronym) study will: (1) evaluate the performance of different triage techniques to detect cervical precancer and (2) inform on how to implement HPV-based screening programmes in LMIC.Methods and analysisWomen aged 30–64 years are screened with HPV testing and Pap across 12 study centres in Latin America. Screened positives have colposcopy with biopsy and treatment of lesions. Women with no evident disease are recalled 18 months later for another HPV test; those HPV-positive undergo colposcopy with biopsy and treatment as needed. Biological specimens are collected in different visits for triage testing, which is not used for clinical management. The study outcome is histological high-grade squamous intraepithelial or worse lesions (HSIL+) under the lower anogenital squamous terminology. About 50 000 women will be screened and 500 HSIL+ cases detected (at initial and 18 months screening). Performance measures (sensitivity, specificity and predictive values) of triage techniques to detect HSIL+ will be estimated and compared with adjustment by age and study centre.Ethics and disseminationThe study protocol has been approved by the Ethics Committee of the International Agency for Research on Cancer (IARC), of the Pan American Health Organisation (PAHO) and by those in each participating centre. A Data and Safety Monitoring Board (DSMB) has been established to monitor progress of the study, assure participant safety, advice on scientific conduct and analysis and suggest protocol improvements. Study findings will be published in peer-reviewed journals and presented at scientific meetings.Trial registration numberNCT01881659

Policies and processes for human papillomavirus vaccination in Latin America and the Caribbean

2017 ◽  
pp. 1-8
Author(s):  
Fernando De la Hoz Restrepo ◽  
Nelson Alvis Guzman ◽  
Alejandro De la Hoz Gomez ◽  
Cuauhtémoc Ruiz
Keyword(s):  
Latin America ◽  
Human Papillomavirus ◽  
Human Papillomavirus Vaccination ◽  
The Caribbean

Biomarkers of human papillomavirus ( HPV )‐driven head and neck cancer in Latin America and Europe study: Study design and HPV DNA /p16 INK4a status

Head & Neck ◽  
2021 ◽  
Author(s):  
Laura Sichero ◽  
Marta Tagliabue ◽  
Giana Mota ◽  
Silvaneide Ferreira ◽  
Rafaella A. L. Nunes ◽  
...  
Keyword(s):  
Latin America ◽  
Head And Neck Cancer ◽  
Human Papillomavirus ◽  
Head And Neck ◽  
Study Design ◽  
Neck Cancer ◽  
Hpv Dna ◽  
P16 Ink4a

Human Papillomavirus Vaccine Policy and Delivery in Latin America and the Caribbean

Vaccine ◽  
2008 ◽  
Vol 26 ◽  
pp. L80-L87 ◽  
Author(s):  
Jon Kim Andrus ◽  
Merle J. Lewis ◽  
Sue J. Goldie ◽  
Patricia J. García ◽  
Jennifer L. Winkler ◽  
...  
Keyword(s):  
Latin America ◽  
Human Papillomavirus ◽  
Human Papillomavirus Vaccine ◽  
The Caribbean ◽  
Papillomavirus Vaccine

scholarly journals Eliminating Deaths From Cervical Cancer—Report of a Panel at the 7th Annual Symposium on Global Cancer Research, a Satellite Meeting at the Consortium of Universities for Global Health 10th Annual Meeting

2019 ◽  
pp. 1-7
Author(s):  
Agnes Binagwaho ◽  
Patricia J. Garcia ◽  
Babacar Gueye ◽  
J. Andrew Dykens ◽  
Nothemba Simelela ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Cancer Research ◽  
Latin America ◽  
Human Papillomavirus ◽  
Global Health ◽  
World Health Organization ◽  
World Health ◽  
Annual Symposium ◽  
Human Papillomavirus Vaccination ◽  
Health Organization

This is a summary of the presentations addressing approaches and achievements to reach the goal of eliminating cervical cancer as a global public health problem that were delivered at the 7th Annual Symposium on Global Cancer Research at the 10th Annual Consortium of Universities for Global Health Meeting in March 2019. Dr Princess Nothemba Simelela, Assistant Director-General for Family, Women, Children and Adolescents, World Health Organization, gave an introduction to the World Health Organization–led Cervical Cancer Elimination Initiative and the emerging conceptual framework and targets that will shape the global 2020 to 2030 strategy. Subsequent presentations shared experiences from national programs in Rwanda (Agnes Binagwaho), Latin America (Patricia J. Garcia), and Senegal (Babacar Gueye and J. Andrew Dykens. Successes in intensified human papillomavirus vaccination and screening with follow-up treatment of early and advanced lesions detected are highlighted as well as the challenges and obstacles in achieving and maintaining high coverage in Africa and Latin America. With strong political leadership, commitment of national stakeholders, and the use of proven and cost-effective approaches to human papillomavirus vaccination, screening, and treatment, the vision of a world free of cervical cancer and saving women’s lives every year by preventing deaths from cervical cancer will be achievable in the next generation in all countries.

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