From Stores to Sinks: Structural Mechanisms of Cytosolic Calcium Regulation

Author(s):  
Masahiro Enomoto ◽  
Tadateru Nishikawa ◽  
Naveed Siddiqui ◽  
Steve Chung ◽  
Mitsuhiko Ikura ◽  
...  
Cell Calcium ◽  
2010 ◽  
Vol 48 (1) ◽  
pp. 44-53 ◽  
Author(s):  
Rebecca Rachael Foster ◽  
Gavin I. Welsh ◽  
Simon C. Satchell ◽  
Robin D. Marlow ◽  
Mathew D. Wherlock ◽  
...  

Cell Calcium ◽  
2013 ◽  
Vol 54 (6) ◽  
pp. 416-427 ◽  
Author(s):  
Michael Henrich ◽  
Keith J. Buckler

1989 ◽  
Vol 139 (3) ◽  
pp. 632-640 ◽  
Author(s):  
E. W. Black ◽  
T. L. Cornwell ◽  
T. M. Lincoln ◽  
S. J. Strada ◽  
W. J. Thompson

2010 ◽  
Vol 12 (7) ◽  
pp. 809-818 ◽  
Author(s):  
Mariclair A. Reeves ◽  
Frederick P. Bellinger ◽  
Marla J. Berry

2014 ◽  
Vol 14 (02) ◽  
pp. 1450022 ◽  
Author(s):  
SUNIL PANDAY ◽  
KAMAL RAJ PARDASANI

At various stages of fertilization specific spatial and temporal patterns of Ca 2+ are required for oocyte maturation. It is crucial to understand the mechanics of Ca 2+ regulation in cytosol of oocytes, in order to have better understanding of fertilization process. In this paper, a finite element model of cytosolic calcium regulation in oocyte has been developed for a two-dimensional unsteady state case. The model incorporates the important biophysical processes like diffusion, reaction, leak from endoplasmic recticulum (ER), efflux from cytosol to ER via sarco-ER calcium adenosine triphosphate (SERCA) pumps, buffers and sodium calcium exchanger. Appropriate boundary conditions have been framed. The effect of source, buffer, sodium calcium exchanger, etc. on spatial and temporal patterns of calcium in oocyte have been studied with the help of numerical results.


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