Evaluation of Glycemic Control Indexes During Pregnancy: The Role of HbA1c, Glycated Albumin, and Fructosamine

2017 ◽  
pp. 29-37
Author(s):  
Maria Boyadzhieva
Keyword(s):  
Glycemic Control ◽  
Glycated Albumin

The Role of Secrecy and Disclosure in Type 1 Diabetes Adherence and Glycemic Control

2013 ◽  
Author(s):  
P. Osborn ◽  
C. A. Berg ◽  
A. E. Hughes ◽  
P. Pham ◽  
D. J. Wiebe
Keyword(s):  
Type 1 Diabetes ◽  
Glycemic Control

The role of diabetic educational programs in glycemic control in patients attending to our day hospital

2017 ◽  
Author(s):  
Mariana Tome ◽  
Pinillos Guillermo Martinez de ◽  
Fernando Garcia ◽  
Eyvee Arturo Cuellar ◽  
Ignacio Fernandez ◽  
...  
Keyword(s):  
Glycemic Control ◽  
Educational Programs ◽  
Day Hospital

Serum glycated albumin: Potential use as an index of glycemic control in diabetic dogs

2008 ◽  
Vol 33 (5) ◽  
pp. 473-479 ◽  
Author(s):  
T. Sako ◽  
A. Mori ◽  
P. Lee ◽  
T. Sato ◽  
H. Mizutani ◽  
...  
Keyword(s):  
Glycemic Control ◽  
Glycated Albumin ◽  
Diabetic Dogs ◽  
Potential Use

Emerging Strategies for the Management of Glycemic Control: The Role of Incretin Enhancers

2006 ◽  
Vol 35 ◽  
pp. 17-19 ◽  
Author(s):  
Bernard Zinman ◽  
Ricard Pratley ◽  
Robert Ratner
Keyword(s):  
Glycemic Control

scholarly journals Results of a Study Comparing Glycated Albumin to Other Glycemic Indices

2019 ◽  
Vol 105 (3) ◽  
pp. 677-687 ◽  
Author(s):  
Cyrus V Desouza ◽  
Richard G Holcomb ◽  
Julio Rosenstock ◽  
Juan P Frias ◽  
Stanley H Hsia ◽  
...  
Keyword(s):  
Blood Glucose ◽  
Glycemic Control ◽  
Diabetes Management ◽  
Pearson Correlation ◽  
Glycated Albumin ◽  
Individual Subject ◽  
Glycemic Indices ◽  
Glucose Profiles ◽  
The Individual ◽  
Pearson Correlations

Abstract Context Intermediate-term glycemic control metrics fulfill a need for measures beyond hemoglobin A1C. Objective Compare glycated albumin (GA), a 14-day blood glucose measure, with other glycemic indices. Design 24-week prospective study of assay performance. Setting 8 US clinics. Participants Subjects with type 1 (n = 73) and type 2 diabetes (n = 77) undergoing changes to improve glycemic control (n = 98) or with stable diabetes therapy (n = 52). Interventions GA, fructosamine, and A1C measured at prespecified intervals. Mean blood glucose (MBG) calculated using weekly self-monitored blood glucose profiles. Main Outcome Measures Primary: Pearson correlation between GA and fructosamine. Secondary: magnitude (Spearman correlation) and direction (Kendall correlation) of change of glycemic indices in the first 3 months after a change in diabetes management. Results GA was more concordant (60.8%) with changes in MBG than fructosamine (55.5%) or A1C (45.5%). Across all subjects and visits, the GA Pearson correlation with fructosamine was 0.920. Pearson correlations with A1C were 0.655 for GA and 0.515 for fructosamine (P < .001) and with MBG were 0.590 and 0.454, respectively (P < .001). At the individual subject level, Pearson correlations with both A1C and MBG were higher for GA than for fructosamine in 56% of subjects; only 4% of subjects had higher fructosamine correlations with A1C and MBG. GA had a higher Pearson correlation with A1C and MBG in 82% and 70% of subjects, respectively. Conclusions Compared with fructosamine, GA correlates significantly better with both short-term MBG and long-term A1C and may be more useful than fructosamine in clinical situations requiring monitoring of intermediate-term glycemic control (NCT02489773).

The role of illness schemata in self-care behaviors and glycemic control among patients with type 2 diabetes in Iran

2019 ◽  
Vol 13 (5) ◽  
pp. 474-480 ◽  
Author(s):  
Taiga Shibayama ◽  
Somayeh Tanha ◽  
Yoshiki Abe ◽  
Hiromi Haginoya ◽  
Asadollah Rajab ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Glycemic Control ◽  
Self Care

scholarly journals Definition of the upper reference limit of glycated albumin in blood donors from Italy

2017 ◽  
Vol 56 (1) ◽  
Author(s):  
Chiara Bellia ◽  
Martina Zaninotto ◽  
Chiara Cosma ◽  
Luisa Agnello ◽  
Bruna Lo Sasso ◽  
...  
Keyword(s):  
Blood Donors ◽  
Glycated Albumin ◽  
Specific Reference ◽  
Reference Limit ◽  
Percentile Method ◽  
The Mean ◽  
Definition Of ◽  
Upper Reference Limit ◽  
Mean Glucose

AbstractBackground:Glycated Albumin (GA) has been proposed as a short-term indicator of glycemic homeostasis. The aim of this study is to describe the distribution of GA in a large sample of blood donors from Italy to evaluate whether demographic features, namely age and sex, could influence GA levels and define specific reference limits.Methods:The study included 1334 Italian blood donors. GA was measured using an enzymatic method (quantILab Glycated Albumin, IL Werfen, Germany). The upper reference limit (URL) was calculated using the non-parametric percentile method.Results:A modest, although significant, increase of GA was observed in relation to age (p<0.001), especially in males, where the differences were more pronounced (p<0.001 in males, p=0.003 in females). Slight differences were documented based on sex (12% [11.3–12.8] in males; 12.2% [11.4–13.1] in females; p=0.01). After excluding individuals with fasting plasma glucose ≥7 mmol/L, the calculated GA URL was 14.5% (95% CI: 14.3–14.7). Subjects with GA>14.5% presented a mean age of 48.4±12.2 years, 66.7% were males and the mean glucose was 6.88±2.5 mmol/L.Conclusions:GA in Caucasians shows a similar increasing trend at older ages documented in other ethnicities. The definition of the URL in this population could be useful for both clinical studies, which will clarify the role of GA for diagnosing and monitoring diabetes, and will encourage the introduction of GA in clinical practice.

scholarly journals Role of Sodium-Glucose Cotransporter 2 (SGLT 2) Inhibitors in the Treatment of Type 2 Diabetes

2011 ◽  
Vol 32 (4) ◽  
pp. 515-531 ◽  
Author(s):  
Muhammad A. Abdul-Ghani ◽  
Luke Norton ◽  
Ralph A. DeFronzo
Keyword(s):  
Type 2 Diabetes ◽  
Glycemic Control ◽  
Microvascular Complications ◽  
Tight Glycemic Control ◽  
Β Cell ◽  
Oral Antidiabetic Agents ◽  
Oral Antidiabetic ◽  
Sodium Glucose Cotransporter

Hyperglycemia plays an important role in the pathogenesis of type 2 diabetes mellitus, i.e., glucotoxicity, and it also is the major risk factor for microvascular complications. Thus, effective glycemic control will not only reduce the incidence of microvascular complications but also correct some of the metabolic abnormalities that contribute to the progression of the disease. Achieving durable tight glycemic control is challenging because of progressive β-cell failure and is hampered by increased frequency of side effects, e.g., hypoglycemia and weight gain. Most recently, inhibitors of the renal sodium-glucose cotransporter have been developed to produce glucosuria and reduce the plasma glucose concentration. These oral antidiabetic agents have the potential to improve glycemic control while avoiding hypoglycemia, to correct the glucotoxicity, and to promote weight loss. In this review, we will summarize the available data concerning the mechanism of action, efficacy, and safety of this novel antidiabetic therapeutic approach.

Sign in / Sign up

Export Citation Format

Share Document