The Pulmonary Vascular Barrier: Insights into Structure, Function, and Regulatory Mechanisms

Molecular and Functional Insights Into the Pulmonary Vasculature - Advances in Anatomy, Embryology and Cell Biology ◽

10.1007/978-3-319-68483-3_3 ◽

2017 ◽

pp. 41-61 ◽

Cited By ~ 2

Author(s):

Kaushik Parthasarathi

Keyword(s):

Structure Function ◽

Regulatory Mechanisms

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Microtubule nucleation without a ring?

The Journal of Cell Biology ◽

10.1083/jcb.202101015 ◽

2021 ◽

Vol 220 (3) ◽

Author(s):

Andreas Merdes

Keyword(s):

Structure Function ◽

Regulatory Mechanisms ◽

Microtubule Nucleation ◽

Ring Complex

The native γ-tubulin ring complex is an asymmetric, imperfect template for microtubule nucleation. Wieczorek et al. (2021. J. Cell Biol.https://doi.org/10.1083/jcb.202009146) and Zimmermann et al. (2020. Sci. Adv.https://doi.org/10.1126/sciadv.abe0894) have reconstituted a recombinant complex that allows study of structure–function relationships and regulatory mechanisms.

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Structure-function relationships of cytochrome by the genetic approach: Intragenic revertants derived from frameshift mutations in the apocytochrome gene

Biochimica et Biophysica Acta (BBA) - Bioenergetics ◽

10.1016/s0005-2728(05)80008-8 ◽

1992 ◽

Vol 1101 (2) ◽

pp. 157-161

Author(s):

A COLSON ◽

B EDDERKAOUI ◽

J COPPEE

Keyword(s):

Structure Function ◽

Genetic Approach ◽

Frameshift Mutations

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Malfunctional Reorganization in the Developing Limbo-Prefrontal System in Animals: Implications for Human Psychoses?

Zeitschrift für Neuropsychologie ◽

10.1024//1016-264x.12.1.8 ◽

2001 ◽

Vol 12 (1) ◽

pp. 8-14

Author(s):

Gertraud Teuchert-Noodt ◽

Ralf R. Dawirs

Keyword(s):

Prefrontal Cortex ◽

Mental Disorders ◽

Dentate Gyrus ◽

Cognitive Functions ◽

Experimental Approach ◽

Regulatory Mechanisms ◽

Hippocampal Dentate Gyrus ◽

Non Invasive ◽

Invasive Method ◽

Activity Dependent

Abstract: Neuroplasticity research in connection with mental disorders has recently bridged the gap between basic neurobiology and applied neuropsychology. A non-invasive method in the gerbil (Meriones unguiculus) - the restricted versus enriched breading and the systemically applied single methamphetamine dose - offers an experimental approach to investigate psychoses. Acts of intervening affirm an activity dependent malfunctional reorganization in the prefrontal cortex and in the hippocampal dentate gyrus and reveal the dopamine position as being critical for the disruption of interactions between the areas concerned. From the extent of plasticity effects the probability and risk of psycho-cognitive development may be derived. Advance may be expected from insights into regulatory mechanisms of neurogenesis in the hippocampal dentate gyrus which is obviously to meet the necessary requirements to promote psycho-cognitive functions/malfunctions via the limbo-prefrontal circuit.

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