Modeling of Cellular Systems: Application in Stem Cell Research and Computational Disease Modeling

2018 ◽  
pp. 129-138
Author(s):  
Muhammad Ali ◽  
Antonio del Sol
Keyword(s):  
Stem Cell ◽  
Stem Cell Research ◽  
Disease Modeling ◽  
Cellular Systems

Translating stem cell research to the clinic: A constant crosstalk between basic and applied research

2012 ◽  
Vol 3 (2) ◽  
Author(s):  
Olivier Raineteau
Keyword(s):  
Stem Cell ◽  
Stem Cell Research ◽  
Pluripotent Stem Cells ◽  
Dopaminergic Neurons ◽  
Disease Modeling ◽  
Patient Specific ◽  
Great Promise ◽  
The Road ◽  
Midbrain Dopaminergic Neurons ◽  
Basic And Applied Research

AbstractPluripotent stem cells hold great promise for the generation of patient-specific cells for disease modeling and regenerative medicine. Focusing on a recent study reporting the successful generation of midbrain dopaminergic neurons and their efficient grafting in animal models of Parkinson’s disease, I discuss how crosstalk between basic and applied stem cell research more generally paves the road toward clinical translation.

Application of Nanomaterials in Regulating the Fate of Adipose-derived Stem Cells

2021 ◽  
Vol 16 (1) ◽  
pp. 3-13
Author(s):  
Lang Wang ◽  
Yong Li ◽  
Maorui Zhang ◽  
Kui Huang ◽  
Shuanglin Peng ◽  
...  
Keyword(s):  
Stem Cells ◽  
Stem Cell ◽  
Stem Cell Research ◽  
Adult Stem Cells ◽  
Adipose Derived Stem Cells ◽  
Proliferation And Differentiation ◽  
Recent Developments ◽  
Good Biocompatibility ◽  
Regulatory Effects ◽  
New Treatment

Adipose-derived stem cells are adult stem cells which are easy to obtain and multi-potent. Stem-cell therapy has become a promising new treatment for many diseases, and plays an increasingly important role in the field of tissue repair, regeneration and reconstruction. The physicochemical properties of the extracellular microenvironment contribute to the regulation of the fate of stem cells. Nanomaterials have stable particle size, large specific surface area and good biocompatibility, which has led them being recognized as having broad application prospects in the field of biomedicine. In this paper, we review recent developments of nanomaterials in adipose-derived stem cell research. Taken together, the current literature indicates that nanomaterials can regulate the proliferation and differentiation of adipose-derived stem cells. However, the properties and regulatory effects of nanomaterials can vary widely depending on their composition. This review aims to provide a comprehensive guide for future stem-cell research on the use of nanomaterials.

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