scholarly journals Management of Fluid Overload in the Pediatric ICU

2018 ◽  
pp. 193-209
Author(s):  
Grace L. Ker ◽  
Sandeep Gangadharan
Keyword(s):  
2019 ◽  
Vol 66 (2) ◽  
pp. 152-162 ◽  
Author(s):  
Ahmed El-Nawawy ◽  
Azza A Moustafa ◽  
Manal A M Antonios ◽  
May M Atta

Abstract Background Fluid overload (FO) has been accused as being one of the ICU problems affecting morbidity and mortality. The aim of the study was to assess the effect and critical threshold of FO that is related to mortality. Methods This prospective observational study was conducted in a pediatric ICU. All patients admitted (n = 203) during 12 months with a length of stay more than 48 h were recruited. Results FO was found to be related to mortality (p = 0.025) but was not proved to be an independent risk factor of fatal outcome by the logistic regression model. This raises the suspicion about any cause—effect relationship between FO and mortality. Even though, FO was statistically a fair discriminator of death (AUC = 0.655, p = 0.0008) and a cutoff level of FO was set at 7%. Kaplan–Meier curve showed that cumulative of survival differed significantly between groups of patients with FO more and less than 7% (p = 0.002) Conclusion Frequent and accurate monitoring of FO is crucial among critically ill patients. The present study suggested a threshold of 7% FO beyond which a more conservative regimen of fluid administration might improve patients’ outcome.


2019 ◽  
Vol 15 (1) ◽  
pp. 12-26
Author(s):  
D. V. Prometnoi ◽  
Yu. S. Aleksandrovich ◽  
K. V. Pshenisnov

Infusion therapy is the main element of treatment of critical illness; at that, it is critical not only to eliminate hypovolemia, but also to prevent fluid overload. The purpose of the study was to identify predictors of a lethal outcome due to the peculiarities of infusion therapy and fluid balance in critically-ill children. Materials and methods. The study included 96 children admitted to the pediatric ICU. The average age of the children was 0.7 (0.2–2) years. Depending on the outcome, all patients were divided into two groups: I — «Recovery», II — «Lethal outcome». The daily volume of administered fluid, the volume of infusion therapy, the volume of pathological losses and fluid balance were estimated. Results. On the first day of therapy, parameters related to the volume of administered fluid were main factors that increased the probability of a lethal outcome; then mortality was associated with parameters related to the volume of discharged fluid. The volume of discharged fluid less than 20% of the administered volume increased the risk of a lethal outcome by 12-fold; the increase in the volume of fluid loss to 80% of the administered one contributed to a significant reduction in the risk of children's death. Conclusion. Positive fluid balance due to reduced volume of the discharged liquid is a major risk factor of a lethal outcome in children.


1982 ◽  
Vol 37 (5) ◽  
pp. 329-330
Author(s):  
WILLIAM O. TARNOW-MORDI ◽  
JONATHAN C. L. SHAW ◽  
DAVID LIU ◽  
DAVID A. GARDNER ◽  
FREDERICK V. FLYNN
Keyword(s):  

Author(s):  
Renate Wendler
Keyword(s):  

Children ◽  
2021 ◽  
Vol 8 (2) ◽  
pp. 59
Author(s):  
Andrew Kampfschulte ◽  
Matthew Oram ◽  
Alejandra M. Escobar Vasco ◽  
Brittany Essenmacher ◽  
Amy Herbig ◽  
...  

Suicide frequency has tripled for some pediatric age groups over the last decade, of which, serious attempts result in pediatric intensive care unit (PICU) admissions. We paired clinical, aggregate geospatial, and temporal demographics to understand local community variables to determine if epidemiological patterns emerge that associate with risk for PICU admission. Data were extracted at an urban, high-volume, quaternary care facility from January 2011 to December 2017 via ICD 10 codes associated with suicide. Clinical, socioeconomic, geographical, and temporal variables were reviewed. In total, 1036 patients over the age of 9 were included, of which n = 161 were PICU admissions. Females represented higher proportions of all suicide-related hospital admissions (67.9%). Looking at race/ethnicity, PICU admissions were largely Caucasian (83.2%); Blacks and Hispanics had lower odds of PICU admissions (OR: 0.49; 0.17, respectively). PICU-admitted patients were older (16.0 vs. 15.5; p = 0.0001), with lower basal metabolic index (23.0 vs. 22.0; p = 0.0013), and presented in summer months (OR: 1.51, p = 0.044). Time-series decomposition showed seasonal peaks in June and August. Local regions outside the city limits identified higher numbers of PICU admissions. PICUs serve discrete geographical regions and are a source of information, when paired with clinical geospatial/seasonal analyses, highlighting clinical and societal risk factors associated with PICU admissions.


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