Comparison of Prospective and Retrospective Environmental Risk Assessments of Human Pharmaceuticals

2008 ◽  
pp. 385-391
Author(s):  
T. Knacker ◽  
M. Liebig ◽  
J. F. Moltmann
Keyword(s):  
Environmental Risk ◽  
Risk Assessments

scholarly journals Quantitative environmental risk assessments in the context of marine spatial management: current approaches and some perspectives

2014 ◽  
Vol 72 (3) ◽  
pp. 1022-1042 ◽  
Author(s):  
V. Stelzenmüller ◽  
H. O. Fock ◽  
A. Gimpel ◽  
H. Rambo ◽  
R. Diekmann ◽  
...  
Keyword(s):  
Risk Analysis ◽  
Environmental Risk ◽  
Risk Evaluation ◽  
Bayesian Belief Network ◽  
Risk Identification ◽  
Offshore Wind ◽  
Risk Assessments ◽  
Spatially Explicit ◽  
Belief Network ◽  
Spatial Management

Abstract Marine spatial planning (MSP) requires spatially explicit environmental risk assessment (ERA) frameworks with quantitative or probabilistic measures of risk, enabling an evaluation of spatial management scenarios. ERAs comprise the steps of risk identification, risk analysis, and risk evaluation. A review of ERAs in in the context of spatial management revealed a synonymous use of the concepts of risk, vulnerability and impact, a need to account for uncertainty and a lack of a clear link between risk analysis and risk evaluation. In a case study, we addressed some of the identified gaps and predicted the risk of changing the current state of benthic disturbance by bottom trawling due to future MSP measures in the German EEZ of the North Sea. We used a quantitative, dynamic, and spatially explicit approach where we combined a Bayesian belief network with GIS to showcase the steps of risk characterization, risk analysis, and risk evaluation. We distinguished 10 benthic communities and 6 international fishing fleets. The risk analysis produced spatially explicit estimates of benthic disturbance, which was computed as a ratio between relative local mortality by benthic trawling and the recovery potential after a trawl event. Results showed great differences in spatial patterns of benthic disturbance when accounting for different environmental impacts of the respective fleets. To illustrate a risk evaluation process, we simulated a spatial shift of the international effort of two beam trawl fleets, which are affected the most by future offshore wind development. The Bayesian belief network (BN) model was able to predict the proportion of the area where benthic disturbance likely increases. In conclusion, MSP processes should embed ERA frameworks which allow for the integration of multiple risk assessments and the quantification of related risks as well as uncertainties at a common spatial scale.

scholarly journals Problem formulation for gene drive mosquitoes designed to reduce malaria transmission in Africa: results from four regional consultations 2016–2018

2019 ◽  
Vol 18 (1) ◽  
Author(s):  
John L. Teem ◽  
Aggrey Ambali ◽  
Barbara Glover ◽  
Jeremy Ouedraogo ◽  
Diran Makinde ◽  
...  
Keyword(s):  
Risk Assessment ◽  
Human Health ◽  
Environmental Risk ◽  
Environmental Risk Assessment ◽  
Early Stage ◽  
Problem Formulation ◽  
Risk Assessments ◽  
Gene Drive ◽  
Starting Point ◽  
Protection Goals

Abstract Background Gene drive mosquitoes have been proposed as a possible means to reduce the transmission of malaria in Africa. Because this technology has no prior use-history at this time, environmental risk assessments for gene drive mosquitoes will benefit from problem formulation—an organized and ordered process to identify protection goals and potential pathways to harm to the environment, or animal or human health. Recognizing this need, the New Partnership for Africa’s Development (NEPAD), with support from African and international partners, organized four regional consultative workshops in Africa to initiate this process. Methods The workshops were attended by a diverse set of participants and stakeholders, including scientists, ethicists, health professionals, government regulators in the fields of environment health and biosafety as well government policymakers, who met for 4 days to deliberate on protection goals and pathways relevant to the use of gene drive mosquitoes for malaria control. The goal of the workshops was not to produce a comprehensive and detailed environmental risk assessment of gene drive mosquitoes, but rather to introduce problem formulation as a tool to the stakeholder community, and to serve as a starting point for conducting systematic environmental risk assessments in the future, identifying protection goals related to gene drive mosquitoes that are particular to African stakeholders. Results Participants in the workshops frequently identified human health and biodiversity as being relevant broad protection goals. Results of the deliberations provide insight into the concerns of African participants at an early stage in the development of gene drive organism/products that should be instructive to developers using this technology. Conclusions In general, the African participants of the consultations had a precautionary perspective with regard to environmental risk assessment of gene drive technology. As gene drive technology develops, protection goals will become further refined and candidate products will be further defined. These workshops represent only the beginning of a continuing process that will ultimately inform environmental risk assessment for gene drive mosquitoes to control malaria in Africa.

Tenax extraction as a simple approach to improve environmental risk assessments

2015 ◽  
Vol 34 (7) ◽  
pp. 1445-1453 ◽  
Author(s):  
Amanda D. Harwood ◽  
Samuel A. Nutile ◽  
Peter F. Landrum ◽  
Michael J. Lydy
Keyword(s):  
Environmental Risk ◽  
Simple Approach ◽  
Risk Assessments

Wind Farms and Biodiversity: Improving Environmental Risk Assessments

2014 ◽  
pp. 41-58
Author(s):  
I. K. G. Boothroyd ◽  
L. P. Barea
Keyword(s):  
Environmental Risk ◽  
Wind Farms ◽  
Risk Assessments

Estimating emissions from adhesives and sealants uses and manufacturing for environmental risk assessments

2015 ◽  
Vol 12 (1) ◽  
pp. 185-194 ◽  
Author(s):  
Johannes Tolls ◽  
Divina Gómez ◽  
Walter Guhl ◽  
Torsten Funk ◽  
Erich Seger ◽  
...  
Keyword(s):  
Environmental Risk ◽  
Risk Assessments
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