Soft computing has attracted many research scientists, decision makers and practicing researchers in recent years as powerful computational intelligent techniques, for solving unlimited number of complex real-world problems particularly related to research area of optimization. Under the uncertain and turbulence environment, classical and traditional approaches are unable to obtain a complete solution with satisfaction for the real-world problems on optimization. Therefore, new global optimization methods are required to handle these issues seriously. One such method is hybrid Genetic algorithms and Pattern search, a generic, flexible, robust, and versatile framework for solving complex problems of global optimization and search in real-world applications.