Distinguishing Left or Right Temporal Lobe Epilepsy from Controls Using Fractional Anisotropy Asymmetry Analysis

Author(s):  
Hai Li ◽  
Zhong Xue ◽  
Mario F. Dulay ◽  
Amit Verma ◽  
Solomon Wong ◽  
...  
2019 ◽  
Vol 2 (2) ◽  
pp. 01-04
Author(s):  
Simbrón Ribbeck Lourdes ◽  
Sandoval Paredes Josefina ◽  
Amador Sánchez Karen ◽  
Taboada Barajas Jesús

Background and purpose: Temporal lobe epilepsy is the most common focal intractable epilepsy. Uncinate fasciculus is a white fiber bundle that connects the orbitofrontal cortex with the anterior temporal lobe, and is implicated in most of the superior mental functions. There is evidence of uncinate fasciculus as a propagation pathway of seizures from temporal lobe. The aim of the study is to determine uncinate fasciculus alterations in patients with temporal lobe epilepsy, through fractional anisotropy. Methods: Thirty-three patients with temporal lobe epilepsy (10 right and 23 left) were studied. All of them were right-handed and had left hemisphere dominance for language. A 1.5 T MR imaging scanner was used to obtain diffusion tensor imaging (DTI). Fractional anisotropy of uncinate fasciculus was calculated through TBSS (Tract Based Spatial Statistics). Statistical analysis was done using IBM SPSS (v. 25). Results: Fractional anisotropy was higher in right uncinate fasciculus, regardless of epilepsy side. Right uncinate fasciculus, at the insula level, showed lower fractional anisotropy in patients with right temporal lobe epilepsy. Conclusions: Results support the evidence of uncinate fasciculus as a pathway of propagation in temporal lobe epilepsy, specially at insular level.


2020 ◽  
Vol 111 ◽  
pp. 107278
Author(s):  
Sangyu Zhou ◽  
Pingan Xiong ◽  
Hongwei Ren ◽  
Wei Tan ◽  
Yanguo Yan ◽  
...  

2016 ◽  
Vol 11 ◽  
pp. 707-718 ◽  
Author(s):  
Jonathan Wirsich ◽  
Alistair Perry ◽  
Ben Ridley ◽  
Timothée Proix ◽  
Mathieu Golos ◽  
...  

2008 ◽  
Vol 78 (2-3) ◽  
pp. 161-170 ◽  
Author(s):  
Lars Frings ◽  
Kathrin Wagner ◽  
Ulrike Halsband ◽  
Ralf Schwarzwald ◽  
Josef Zentner ◽  
...  

2016 ◽  
Vol 127 ◽  
pp. 252-259 ◽  
Author(s):  
Jianping Li ◽  
Xuemei Chen ◽  
Wei Ye ◽  
Wenyu Jiang ◽  
Huihua Liu ◽  
...  

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