Transient global amnesia with bilateral hippocampal findings in magnetic resonance imaging

Transient global amnesia (TGA) is an unusual neurological syndrome of unknown etiology that affects individuals between 50 and 75 years old. We describe the case of a 61-year-old woman, who experienced an episode of two hours of anterograde amnesia. The event had an acute onset and was observed by a reliable witness. It lacked motor or sensory symptoms, compromised consciousness, or personal identity. A brain magnetic resonance was performed 22 hours after the onset of symptoms depicting foci of restricted diffusion in both hippocampi. Taking into account clinical and imaging findings, the diagnosis of transient global amnesia was made.

Uncinate Fasciculus in Temporal Lobe Epilepsy

Background and purpose: Temporal lobe epilepsy is the most common focal intractable epilepsy. Uncinate fasciculus is a white fiber bundle that connects the orbitofrontal cortex with the anterior temporal lobe, and is implicated in most of the superior mental functions. There is evidence of uncinate fasciculus as a propagation pathway of seizures from temporal lobe. The aim of the study is to determine uncinate fasciculus alterations in patients with temporal lobe epilepsy, through fractional anisotropy. Methods: Thirty-three patients with temporal lobe epilepsy (10 right and 23 left) were studied. All of them were right-handed and had left hemisphere dominance for language. A 1.5 T MR imaging scanner was used to obtain diffusion tensor imaging (DTI). Fractional anisotropy of uncinate fasciculus was calculated through TBSS (Tract Based Spatial Statistics). Statistical analysis was done using IBM SPSS (v. 25). Results: Fractional anisotropy was higher in right uncinate fasciculus, regardless of epilepsy side. Right uncinate fasciculus, at the insula level, showed lower fractional anisotropy in patients with right temporal lobe epilepsy. Conclusions: Results support the evidence of uncinate fasciculus as a pathway of propagation in temporal lobe epilepsy, specially at insular level.

Intellectual Corruption in Modern Science: A Case Study

A reviewer of a book I wrote claimed an idea presented therein could be found elsewhere. Nine years later, no one could say where, but no one would correct the erroneous claim, so what be-gan as an effort to obtain a redress of a legitimate grievance slowly degenerated into a tour d’farce of a surreal ethics warp in our intellectual community. The citations submitted to docu-ment the claim failed to do so, and the file on the dispute maintained by the American Psychological Association (APA) really is not about my case at all. The University of Connecticut (UConn) and the American Association for the Advancement of Sci-ence (AAAS) failed to hold anyone accountable. There was a basic conflict between the conduct of officials of all these organiza-tions and their ethical codes. In a culture of intellectual cor-ruption, behavior consisted of a pervasive and extended cover-up characterized by sophistry, secrecy, fantasy, irrelevance, ra-tionalization, misattribution, misrepresentation, fabrication, falsification, failure to communicate and an adamant refusal to deal logically and fairly with the facts of the case. This demon-strated a complete lack of cognitive integrity and constituted a total betrayal of the academic/scientific commitment to truth.

The role of genetic mutations in genes HSPB1 & HSPB8 in Distal Hereditary Motor Neuropathy, type II Syndrome

Symptoms of DHMN2 usually begin from the age of 10 to the middle of adulthood. Early signs of this disorder include clogging or weakness in the muscles of the toe and the next, the whole leg. The DHMN2 syndrome is caused by the mutation of the HSPB1 gene, which is positioned in the long arm of chromosome 7 as 7q11.23, and the HSPB8 gene, which is based on the long arm of chromosome 12, is 12q24.23.

Large Retrospective Study of Traumatic Brain Injury undergo De compressive Craniotomy

Decompressive craniectomy is widely used for treating patients with traumatic brain injury (TBI). Usually patients have dura mater defect due to surgery or injury itself. The defective area may left open or repaired by artificial dura substitutes. A variety of artificial dura substitutes have been used for this purpose.

Cognitive Impairment: A Retrospective Study of Carotid Artery Stenosis

Acute ischemic stroke has been recognized as one key cause of vascular cognitive impairment (VCI). The purpose of this study was to evaluate the correlation between carotid artery stenosis and post VCI in acute ischemic stroke patients.

Parkinson's disease: Role of Acupuncture Study a Randomized Study of Fatigue Behavior

Fatigue is a common and disabling problem in patients with Parkinson's disease (PD), and there is currently no satisfactory treatment. As acupuncture has been reported to be effective in fatigue related to other conditions, we sought to evaluate its efficacy in PD.

Aging and Poverty in Asian Context: A Sociological Appraisal of Alzheimer's Disorders in Iran

The paper reflects an image of Alzheimer's disorders in Asia as the largest continent of the world. Asia with increasing life expectancy and elderly people is facing Alzheimer's disorders within the emerging aging people leaving behind various issues. Aging in Asia is also in parallel with poverty and health deficiency. Many parts of Asia is getting aged before becoming rich. Spread of Alzheimer's disorders while needing more and additional capital to invest, is in low position. Under such circumstances, the countries of the region need new paradigms and policies to combat the emerging Alzheimer's within the aging cohorts. Aging as a new phase of life needs new strategies to put into effect, to take care of those involved with Alzheimer's disorders. Aging as a new part of life needs more scientific study, and the practice of plans to modify the issue.

A Review of Cerebral Edema, Cerebral Perfusion, and Intracranial Pressure Elevations in Acute Sickness

We hypothesized that cerebral alterations in edema, perfusion, and/or intracranial pressure (ICP) are related to the development of acute mountain sickness (AMS).