Manipulation Technologies for Molecular Robots

2021 ◽  
pp. 1-9
Author(s):  
Masahiro Takinoue
Keyword(s):  
APL Materials ◽  
2020 ◽  
Vol 8 (10) ◽  
pp. 101104
Author(s):  
Ting-Yen Wei ◽  
Warren C. Ruder

Micromachines ◽  
2020 ◽  
Vol 11 (9) ◽  
pp. 788 ◽  
Author(s):  
Kan Shoji ◽  
Ryuji Kawano

A molecular robot is a microorganism-imitating micro robot that is designed from the molecular level and constructed by bottom-up approaches. As with conventional robots, molecular robots consist of three essential robotics elements: control of intelligent systems, sensors, and actuators, all integrated into a single micro compartment. Due to recent developments in microfluidic technologies, DNA nanotechnologies, synthetic biology, and molecular engineering, these individual parts have been developed, with the final picture beginning to come together. In this review, we describe recent developments of these sensors, actuators, and intelligence systems that can be applied to liposome-based molecular robots. First, we explain liposome generation for the compartments of molecular robots. Next, we discuss the emergence of robotics functions by using and functionalizing liposomal membranes. Then, we discuss actuators and intelligence via the encapsulation of chemicals into liposomes. Finally, the future vision and the challenges of molecular robots are described.


2013 ◽  
Vol 53 (supplement1-2) ◽  
pp. S232
Author(s):  
Yuichi Tsuganezawa ◽  
Masamune Morita ◽  
Shogo Hamada ◽  
Shin-ichiro M. Nomura ◽  
Kenzo Fujimoto ◽  
...  

2018 ◽  
Author(s):  
Daisuke Ishikawa ◽  
Yuki Suzuki ◽  
Chikako Kurokawa ◽  
Masayuki Ohara ◽  
Misato Tsuchiya ◽  
...  

Bio-inspired functional microcapsules stabilised with surfactants, copolymers, and nano/microparticles have attracted much attention in many fields from physical/chemical science to artificial cell engineering. Although the particle-stabilized microcapsules have advantages for their stability and rich ways for functionalisation such as surface chemical modifications and shape control of particles, versatile methods for their designable functionalisation are desired to expand their possibilities. Here, we report a DNA-based microcapsule composed of a water-in-oil microdroplet stabilised with amphiphilised DNA origami nanoplates. By utilising function programmability achieved by DNA nanotechnology, the DNA nanoplates were designed as a nanopore device for ion transportation as well as the interface stabiliser. Microscopic observations showed that the microcapsule formed by amphiphilic DNA nanoplates accumulated at the oil-water interface. Ion current measurements demonstrated that pores in the nanoplates functioned as ion channels. These findings provide a general strategy for programmable designing of microcapsules for engineering artificial cells and molecular robots.<br>


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