Epileptogenesis and the Immature Brain II. Subcortical Mechanisms

1991 ◽  
pp. 151-153
Author(s):  
S. L. Moshé ◽  
G. L. Holmes ◽  
P. Mareš
Keyword(s):  
Immature Brain

Integrative Cortical Functions in the Immature Brain – Investigations in Human Newborns using EEG

2004 ◽  
Vol 35 (03) ◽  
Author(s):  
M Eiselt ◽  
K Schwab ◽  
P Putsche ◽  
H Witte ◽  
U Zwiener
Keyword(s):  
Immature Brain ◽  
Cortical Functions

AUTISM AS A DISORDER OF THE IMMATURE BRAIN

2006 ◽  
Vol 37 (S 1) ◽  
Author(s):  
I Rapin
Keyword(s):  
Immature Brain

Cannabinoids enhance the susceptibility of the immature brain to ethanol neurotoxicity

2006 ◽  
Vol 37 (06) ◽  
Author(s):  
B Krutz ◽  
HH Hansen ◽  
M Sifringer ◽  
P Bittigau ◽  
F Pragst ◽  
...  
Keyword(s):  
Immature Brain

Targeting the vasculature for cerebroprotection in the immature brain

2014 ◽  
Vol 261 ◽  
pp. 551-552
Author(s):  
H. Hagberg ◽  
C.J. Ek
Keyword(s):  
Immature Brain

Is Childhood General Anesthesia Exposure An Etiological Contributor to Cognitive Impairment?

2021 ◽  
Vol 36 (3) ◽  
pp. 251-259
Author(s):  
Yi Tian ◽  
Peiyu Liu ◽  
Weisong Liu ◽  
Qiaojing Xu ◽  
Xiangkun Zhao
Keyword(s):  
Risk Factors ◽  
Early Childhood ◽  
Cognitive Impairment ◽  
General Anesthesia ◽  
Strong Correlation ◽  
Clinical Studies ◽  
Clinical Evidence ◽  
Preclinical Studies ◽  
Invasive Procedures ◽  
Immature Brain

General anesthesia is necessary for patients to undergo surgery and invasive procedures. However, numerous preclinical studies have demonstrated widespread developmental neurotoxicity of the commonly used anesthetics and sedatives for the immature brain. Clinical studies also suggest a strong correlation between childhood anesthesia exposure and subsequent behavioral or cognitive impairment in adulthood. These findings have attracted increasing attention of anesthesiologists, pediatricians, and caregivers about the safety of anesthesia exposure in children, especially during early childhood. Herein, the aim of this review was to present the molecular mechanism of general anesthesia and its effects on the developing brain and introduce the recent clinical evidence of changes in cognition function post-childhood general anesthesia exposure. More importantly, some of the spots will be importantly discussed to scrutinize the phenomena; only in this way, it may help minimize or eliminate relevant risk factors.

scholarly journals The Ischemic Immature Brain: Views on Current Experimental Models

2018 ◽  
Vol 12 ◽  
Author(s):  
Tânia Faustino-Mendes ◽  
Marta Machado-Pereira ◽  
Miguel Castelo-Branco ◽  
Raquel Ferreira
Keyword(s):  
Experimental Models ◽  
Immature Brain
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