Genetic Resistance to Marek’s Disease

2001 ◽  
pp. 121-141 ◽  
Author(s):  
L. D. Bacon ◽  
H. D. Hunt ◽  
H. H. Cheng
Keyword(s):  
Genetic Resistance ◽  
Marek's Disease ◽  
Marek’S Disease

Genetic resistance to two Marek's disease viruses and its relationship to production traits in chickens

1992 ◽  
Vol 72 (2) ◽  
pp. 213-225 ◽  
Author(s):  
H. Ameli ◽  
J. S. Gavora ◽  
R. W. Fairfull ◽  
J. L. Spencer
Keyword(s):  
Egg Production ◽  
Genetic Correlations ◽  
Genetic Resistance ◽  
Total Mortality ◽  
Marek's Disease ◽  
Production Test ◽  
Production Traits ◽  
Marek’S Disease ◽  
Genetic Groups ◽  
Challenge Tests

Genetic variability of resistance to Marek's Disease (MD), and relationships between MD incidence and egg production traits were studied in 23 genetic groups of experimental and commercial meat and egg chickens. In the challenge tests, chickens were injected with either moderately virulent BC-1 MD virus (BC-1) or highly virulent RB-1B MD virus (RB-1B). In the 497-d egg-production test, sisters of challenged birds were vaccinated for MD on the day of hatch and there were no outbreaks of MD. Heritabilities for MD incidence, MD mortality, and total mortality in the challenge tests, based on data from three unselected control strains of Leghorns were generally low (0.06, 0.13 and 0.20) with BC-1. With RB-1B, the heritability estimates were significantly (P <.05) higher (0.62, 1.00 and 0.96). Intraclass correlations, based on variation between and within the genetic groups were also higher with RB-1B. In the test with BC-1 there were deaths from an early mortality syndrome (EMS) prior to development of MD. Losses from EMS in Leghorns were highest in 2 genetic groups most resistant to MD. Based on genetic group means, correlations between MD incidence and egg production and egg weight were high and negative. In contrast the correlations between MD incidence, age at first egg, total blood spots, and egg specific gravity tended to be positive. No consistent relationships were found with adult body weight. Key words: Marek's disease, genetic resistance, heritability, genetic correlations, production traits, chickens

Host genetic resistance to Marek's disease sustains protective efficacy of herpesvirus of turkey in both experimental and commercial lines of chickens

Vaccine ◽  
2014 ◽  
Vol 32 (16) ◽  
pp. 1820-1827 ◽  
Author(s):  
Shuang Chang ◽  
Qingmei Xie ◽  
John R. Dunn ◽  
Catherine W. Ernst ◽  
Jiuzhou Song ◽  
...  
Keyword(s):  
Protective Efficacy ◽  
Genetic Resistance ◽  
Marek's Disease ◽  
Marek’S Disease ◽  
Host Genetic

Validation of Alternative Transcript Splicing in Chicken Lines that Differ in Genetic Resistance to Marek’s Disease

2016 ◽  
Vol 27 (4) ◽  
pp. 238-244 ◽  
Author(s):  
Muhammet Kaya ◽  
Likit Preeyanon ◽  
Jerry B. Dodgson ◽  
Hans H. Cheng
Keyword(s):  
Genetic Resistance ◽  
Marek's Disease ◽  
Alternative Transcript ◽  
Marek’S Disease

Quantitative analysis of Marek's disease vaccine virus in relation to host genetic resistance

1998 ◽  
Vol 27 (sup1) ◽  
pp. S89-S89 ◽  
Author(s):  
S. M. Sellers ◽  
T. F. Davison ◽  
N. Bumstead
Keyword(s):  
Quantitative Analysis ◽  
Genetic Resistance ◽  
Vaccine Virus ◽  
Marek's Disease ◽  
Marek’S Disease ◽  
Host Genetic

scholarly journals Using Integrative Genomics to Elucidate Genetic Resistance to Marek’s Disease in Chickens

2008 ◽  
pp. 365-372 ◽  
Author(s):  
H. Cheng ◽  
M. Niikura ◽  
T. Kim ◽  
W. Mao ◽  
K.S. MacLea ◽  
...  
Keyword(s):  
Genetic Resistance ◽  
Marek's Disease ◽  
Marek’S Disease ◽  
Integrative Genomics
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