Lipid Membrane Self-Assembly and Nonlamellar Phase Transitions

1986 ◽  
pp. 38-47
Author(s):  
Derek Marsh
Keyword(s):  
Phase Transitions ◽  
Self Assembly ◽  
Lipid Membrane

scholarly journals Electrochemical Properties of Lipid Membranes Self-Assembled from Bicelles

Membranes ◽  
2020 ◽  
Vol 11 (1) ◽  
pp. 11
Author(s):  
Damian Dziubak ◽  
Kamil Strzelak ◽  
Slawomir Sek
Keyword(s):  
Electrochemical Properties ◽  
Self Assembly ◽  
Lipid Membranes ◽  
Lipid Membrane ◽  
Membrane Resistance ◽  
Electrochemical Characteristics ◽  
Freeze Thaw ◽  
Lipid Films ◽  
Supported Lipid Membranes

Supported lipid membranes are widely used platforms which serve as simplified models of cell membranes. Among numerous methods used for preparation of planar lipid films, self-assembly of bicelles appears to be promising strategy. Therefore, in this paper we have examined the mechanism of formation and the electrochemical properties of lipid films deposited onto thioglucose-modified gold electrodes from bicellar mixtures. It was found that adsorption of the bicelles occurs by replacement of interfacial water and it leads to formation of a double bilayer structure on the electrode surface. The resulting lipid assembly contains numerous defects and pinholes which affect the permeability of the membrane for ions and water. Significant improvement in morphology and electrochemical characteristics is achieved upon freeze–thaw treatment of the deposited membrane. The lipid assembly is rearranged to single bilayer configuration with locally occurring patches of the second bilayer, and the number of pinholes is substantially decreased. Electrochemical characterization of the lipid membrane after freeze–thaw treatment demonstrated that its permeability for ions and water is significantly reduced, which was manifested by the relatively high value of the membrane resistance.

2-Aminopyrimidine-Silver(I) Based Hybrid Organic Polymers: Self-Assembly and Phase Transitions of a Novel Class of Electronic Material

2010 ◽  
Vol 22 (16) ◽  
pp. 4749-4755 ◽  
Author(s):  
Ion Stoll ◽  
Regina Brockhinke ◽  
Andreas Brockhinke ◽  
Markus Böttcher ◽  
Thomas Koop ◽  
...  
Keyword(s):  
Phase Transitions ◽  
Electronic Material ◽  
Self Assembly ◽  
Organic Polymers

Self-Healing Bilayer Lipid Membranes Formed Over Synthetic Substrates

2008 ◽  
Author(s):  
M. Austin Creasy ◽  
Donald J. Leo
Keyword(s):  
Self Assembly ◽  
Lipid Membranes ◽  
Lipid Membrane ◽  
Bilayer Lipid Membrane ◽  
Unique Property ◽  
Bilayer Lipid Membranes ◽  
Self Healing ◽  
Electrical Field ◽  
Bilayer Lipid ◽  
Recent Experimental Study

Biological systems demonstrate autonomous healing of damage and are an inspiration for developing self-healing materials. Our recent experimental study has demonstrated that a bilayer lipid membrane (BLM), also called a black lipid membrane, has the ability to self-heal after mechanical failure. These molecules have a unique property that they spontaneously self assembly into organized structures in an aqueous medium. The BLM forms an impervious barrier to ions and fluid between two volumes and strength of the barrier is dependent on the pressure and electrical field applied to the membrane. A BLM formed over an aperture on a silicon substrate is shown to self-heal for 5 pressurization failure cycles.

scholarly journals Phase Transition in Di-oleoylphosphatidylglycerol/Monoolein Membranes due to Interactions of Positively Charged Peptides at their Lipid Membrane-Interface

1970 ◽  
Vol 45 (3) ◽  
pp. 219-224
Author(s):  
Shah Md Masum ◽  
Masahito Yamazaki
Keyword(s):  
Phase Transition ◽  
Phase Transitions ◽  
Small Angle ◽  
Lipid Membrane ◽  
Cubic Phase ◽  
Membrane Interface ◽  
X Ray ◽  
X Ray Scattering ◽  
Charged Peptides ◽  
Positively Charged

To elucidate the factors that induce phase transitions in biomembranes due to interactions of proteins/peptides at the lipid membrane-interface, the effects of positively charged peptides on the cubic phase (Q229) of Dioleoylphosphatidylglycerol (DOPG)/Monoolein (MO) membranes were investigated. Small angle X-ray Scattering (SAXS) results revealed that 12 mol% DOPG/88 mol % MO membranes in excess water at 25°C is body centered cubic phase of crystallographic space group Im3m (Q229). In presence of peptide LLKKK, the lattices constant of Q229 phase was gradually decreased with an increase of peptide concentration and a phase transition from cubic (Q229) to cubic (Q224) phase occurred at R=0.080; (R= molar ratio of peptide to lipid). On the other hand the designed peptide WLFLLKKK and antimicrobial peptide Magainin-2 induced lamellar phase (Lα) in the same mixture membranes. These results indicate that the interactions of the these peptides with this mixture membrane are different: LLKKK induces electrostatic attractive interactions and that of WLFLLKKKK and Magainin-2 bound with the lipid membranes induce electrostatic repulsive interaction at the membrane-interface, might be the major factor inducing different phase transitions in 12 mol% DOPG/88mol% MO mixture membranes. Key words: Antimicrobial peptide Magain-2; Dioleoylphosphatidylglycerol; Monoolein; Cubic phases; Small angle X-ray Scattering DOI: 10.3329/bjsir.v45i3.6530Bangladesh J. Sci. Ind. Res. 45(3), 219-224, 2010

Self-assembly of monolayered lipid membranes for surface-coating of a nanoconfined Bombyx mori silk fibroin film

RSC Advances ◽  
2015 ◽  
Vol 5 (81) ◽  
pp. 65684-65689 ◽  
Author(s):  
Fan Xu ◽  
Meimei Bao ◽  
Longfei Rui ◽  
Jiaojiao Liu ◽  
Jingliang Li ◽  
...  
Keyword(s):  
Bombyx Mori ◽  
Silk Fibroin ◽  
Self Assembly ◽  
Lipid Membranes ◽  
Surface Coating ◽  
Lipid Membrane ◽  
Coating Film ◽  
Silk Fibroin Film ◽  
Bombyx Mori Silk ◽  
Self Assembled

A self-assembled lipid membrane provides a smooth, hydrophilic and biocompatible surface coating film for materials.

Structural Phase Transitions of Molecular Self-Assembly Driven by Nonbonded Metal Adatoms

ACS Nano ◽  
2020 ◽  
Vol 14 (5) ◽  
pp. 6331-6338 ◽  
Author(s):  
Shichao Li ◽  
Sai Duan ◽  
Zeqi Zha ◽  
Jinliang Pan ◽  
Luye Sun ◽  
...  
Keyword(s):  
Phase Transitions ◽  
Self Assembly ◽  
Structural Phase ◽  
Structural Phase Transitions

Reaction-induced phase transitions with block copolymers in solution and bulk

2021 ◽  
Vol 12 (1) ◽  
pp. 12-28 ◽  
Author(s):  
Joshua Lequieu ◽  
Andrew J. D. Magenau
Keyword(s):  
Phase Transitions ◽  
Block Copolymers ◽  
Chemical Reactions ◽  
Self Assembly

Reaction-induced phase transitions use chemical reactions to drive macromolecular organisation and self-assembly. This review highlights significant and recent advancements in this burgeoning field.

Biomembrane induced in situ self-assembly of peptide with enhanced antimicrobial activity

2020 ◽  
Vol 8 (7) ◽  
pp. 2031-2039 ◽  
Author(s):  
Zhiwei Shen ◽  
Zhen Guo ◽  
Limin Zhou ◽  
Yujiao Wang ◽  
Jinjin Zhang ◽  
...  
Keyword(s):  
Antimicrobial Activity ◽  
Self Assembly ◽  
Lipid Membrane ◽  
Self Assembled

FF8 self-assembled into nanofibers on the negatively charged lipid membrane and induced rupture of the membrane.

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