Intestinal Calcium Transport: Vesicular Carriers, Noncytoplasmic Calbindin D 28K, and Non-Nuclear Effects of 1,25-Dihydroxyvitamin D3

Author(s):  
I. Nemere
2013 ◽  
Vol 31 (8) ◽  
pp. 685-691 ◽  
Author(s):  
Narattaphol Charoenphandhu ◽  
Kamonshanok Kraidith ◽  
Jarinthorn Teerapornpuntakit ◽  
Kanogwun Thongchote ◽  
Pissared Khuituan ◽  
...  

1991 ◽  
Vol 266 (3) ◽  
pp. 1910-1913
Author(s):  
J Krisinger ◽  
M Strom ◽  
H D Darwish ◽  
K Perlman ◽  
C Smith ◽  
...  

1983 ◽  
Vol 244 (2) ◽  
pp. E159-E163
Author(s):  
S. Okamoto ◽  
Y. Tanaka ◽  
H. F. DeLuca ◽  
Y. Kobayashi ◽  
N. Ikekawa

The biological activity of 24,24-difluoro-1,25-dihydroxyvitamin D3 was compared with 1,25-dihydroxyvitamin D3 in the rat. The 24,24-difluoro-1,25-dihydroxyvitamin D3 has a potency of approximately 5-10 times that of 1,25-dihydroxyvitamin D3 in the known in vivo vitamin D responsive systems. These systems include intestinal calcium transport, bone calcium mobilization, calcification of epiphyseal plate cartilage, and elevation of plasma calcium and phosphorus concentrations. Thus, 24,24-difluoro-1,25-dihydroxyvitamin D3 is the first known analogue with higher potency than 1,25-dihydroxyvitamin D3 in vivo.


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