Interleukin-5 Receptor α Subunit Gene Regulation in Human Eosinophil Development: Identification of a Unique Cis-Element that acts lie an Enhacer in Regulating Activity of the IL-5Rα Promoter

1996 ◽  
pp. 173-187 ◽  
Author(s):  
Z. Sun ◽  
D. A. Yergeau ◽  
I. C. Wong ◽  
T. Tuypens ◽  
J. Tavernier ◽  
...  
Keyword(s):  
Gene Regulation ◽  
Subunit Gene ◽  
Α Subunit ◽  
Human Eosinophil ◽  
Interleukin 5 ◽  
Cis Element

The Murine Interleukin-5 Receptor α-Subunit Gene: Characterization of the Gene Structure and Chromosome Mapping

1994 ◽  
Vol 13 (3) ◽  
pp. 283-292 ◽  
Author(s):  
FUMIYA IMAMURA ◽  
SATOSHI TAKAKI ◽  
KIWAMU AKAGI ◽  
MASAYUKI ANDO ◽  
KEN-ICHI YAMAMURA ◽  
...  
Keyword(s):  
Gene Structure ◽  
Chromosome Mapping ◽  
Subunit Gene ◽  
Α Subunit ◽  
Gene Characterization ◽  
Interleukin 5

scholarly journals Binding Interactions of Human Interleukin 5 with Its Receptor α Subunit

1995 ◽  
Vol 270 (16) ◽  
pp. 9459-9471 ◽  
Author(s):  
Kyung Johanson ◽  
Edward Appelbaum ◽  
Michael Doyle ◽  
Preston Hensley ◽  
Baoguang Zhao ◽  
...  
Keyword(s):  
Binding Interactions ◽  
Α Subunit ◽  
Interleukin 5

Expression of inhibin α-subunit gene during mouse gametogenesis

1990 ◽  
Vol 44 (1) ◽  
pp. 62-68 ◽  
Author(s):  
Shigenobu Tone ◽  
Yuko Katoh ◽  
Hirokazu Fujimoto ◽  
Shin Togashi ◽  
Masako Yanazawa ◽  
...  
Keyword(s):  
Subunit Gene ◽  
Α Subunit

scholarly journals Identification of Heterotrimeric G Protein γ3 Subunit in Rice Plasma Membrane

2018 ◽  
Vol 19 (11) ◽  
pp. 3591 ◽  
Author(s):  
Aki Nishiyama ◽  
Sakura Matsuta ◽  
Genki Chaya ◽  
Takafumi Itoh ◽  
Kotaro Miura ◽  
...  
Keyword(s):  
Plasma Membrane ◽  
Higher Plants ◽  
Rice Genome ◽  
Amino Acid Residues ◽  
Subunit Gene ◽  
Α Subunit ◽  
Γ Subunit ◽  
Domain Antibody ◽  
C Terminus ◽  
Liquid Chromatography Tandem Mass

Heterotrimeric G proteins are important molecules for regulating plant architecture and transmitting external signals to intracellular target proteins in higher plants and mammals. The rice genome contains one canonical α subunit gene (RGA1), four extra-large GTP-binding protein genes (XLGs), one canonical β subunit gene (RGB1), and five γ subunit genes (tentatively named RGG1, RGG2, RGG3/GS3/Mi/OsGGC1, RGG4/DEP1/DN1/OsGGC3, and RGG5/OsGGC2). RGG1 encodes the canonical γ subunit; RGG2 encodes the plant-specific type of γ subunit with additional amino acid residues at the N-terminus; and the remaining three γ subunit genes encode the atypical γ subunits with cysteine abundance at the C-terminus. We aimed to identify the RGG3/GS3/Mi/OsGGC1 gene product, Gγ3, in rice tissues using the anti-Gγ3 domain antibody. We also analyzed the truncated protein, Gγ3∆Cys, in the RGG3/GS3/Mi/OsGGC1 mutant, Mi, using the anti-Gγ3 domain antibody. Based on nano-liquid chromatography-tandem mass spectrometry (LC-MS/MS) analysis, the immunoprecipitated Gγ3 candidates were confirmed to be Gγ3. Similar to α (Gα) and β subunits (Gβ), Gγ3 was enriched in the plasma membrane fraction, and accumulated in the flower tissues. As RGG3/GS3/Mi/OsGGC1 mutants show the characteristic phenotype in flowers and consequently in seeds, the tissues that accumulated Gγ3 corresponded to the abnormal tissues observed in RGG3/GS3/Mi/OsGGC1 mutants.

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