Follow-up of Patients with Well-Differentiated Thyroid Cancer

2001 ◽  
pp. 165-180 ◽  
Author(s):  
B. Shapiro ◽  
M. D. Gross
Keyword(s):  
Thyroid Cancer ◽  
Differentiated Thyroid Cancer ◽  
Well Differentiated

scholarly journals Management of differentiated thyroid cancer diagnosed during pregnancy

1999 ◽  
pp. 404-406 ◽  
Author(s):  
L Vini ◽  
S Hyer ◽  
B Pratt ◽  
C Harmer
Keyword(s):  
Thyroid Cancer ◽  
Bone Metastases ◽  
Differentiated Thyroid Cancer ◽  
Subtotal Thyroidectomy ◽  
Second Trimester ◽  
Original Cohort ◽  
Well Differentiated ◽  
Disease Free ◽  
In Pregnancy

OBJECTIVE: To assess the outcome of thyroid cancer diagnosed during pregnancy. DESIGN: Retrospective analysis of patients diagnosed between 1949 and 1997 with thyroid cancer presenting during pregnancy. RESULTS: Nine women with a median age of 28 years were identified. A thyroid nodule was discovered by the clinician during routine antenatal examination in four cases, the remainder had noted a lump in the neck. In all patients, the nodule was reported to almost double in size during the pregnancy. One patient underwent subtotal thyroidectomy during the second trimester; eight were operated on within 3 to 10 months from delivery. Total thyroidectomy was performed in five and subtotal thyroidectomy in four. All tumours were well differentiated and ranged in size from 1 to 6 cm. OUTCOME: The median follow-up was 14 years (5-31 years). One patient relapsed locally requiring further surgery. One patient developed bone metastases dying 7 years after presentation; her planned treatment had been delayed because of an intervening pregnancy. Eight of the original cohort of patients are currently disease free. CONCLUSIONS: Differentiated thyroid cancer presenting in pregnancy generally has an excellent prognosis. When the disease is discovered early in pregnancy, surgery should be considered in the second trimester but radioiodine scans and treatment can be safely delayed until after delivery. In all cases, treatment should not be delayed for more than a year.

Iodine uptake in the chest in the follow-up of well-differentiated thyroid cancer

2011 ◽  
Vol 30 (1) ◽  
pp. 24-28
Author(s):  
M.P. García Alonso ◽  
M.A. Balsa Bretón ◽  
C. Paniagua Correa ◽  
L. Castillejos Rodríguez ◽  
F.J. Penín González ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Differentiated Thyroid Cancer ◽  
Iodine Uptake ◽  
Well Differentiated

scholarly journals Clinical Course from Diagnosis to Death in Patients with Well-Differentiated Thyroid Cancer

Cancers ◽  
2020 ◽  
Vol 12 (8) ◽  
pp. 2323
Author(s):  
Hyunju Park ◽  
Jun Park ◽  
So Young Park ◽  
Tae Hyuk Kim ◽  
Sun Wook Kim ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Thyroid Carcinoma ◽  
Cause Of Death ◽  
Differentiated Thyroid Cancer ◽  
Causes Of Death ◽  
Clinical Course ◽  
Common Causes ◽  
Regional Disease ◽  
Well Differentiated

Because of the low mortality rate of well-differentiated thyroid cancer (WDTC), investigation of the clinical course leading to death is limited. We analyzed the cause of death and clinical course from diagnosis to death in patients who died of WDTC. A total of 592 WDTC patients died between 1996 and 2018. After exclusion, 79 patients were enrolled and divided into four groups based on their clinical course; that is, inoperable at the time of diagnosis (inoperable), distant metastasis (DM) detected at the time of diagnosis (initial-DM), DM detected during follow-up (late-DM), and loco-regional disease (L-R). Lung (55.6%) in papillary thyroid carcinoma (PTC) and bone (46.7%) in follicular thyroid carcinoma (FTC) were the most common metastasis locations. The most common causes of death were respiratory failure (32.3%) and airway obstruction (30.6%) in PTC, and complications due to immobilization arising from bone metastasis (35.3%) in FTC. Brain metastasis was found in 13.3% of patients and had the worst prognosis. The overall survival (OS) differed significantly (p = 0.001) according to clinical course; the inoperable had the shortest survival, followed by the initial-DM, L-R, and late-DM. However, OS did not differ significantly between PTC and FTC patients with initial-DM (p = 0.83). Other causes of death were far more common than death resulting from WDTC. In patients dying of WDTC, the major cause of death varied by metastatic site. OS differed according to clinical course, but not histologic type. Timing and DM sites differed between PTC and FTC.

Primary versus tertiary care follow-up of low risk well differentiated thyroid cancer

2017 ◽  
Author(s):  
Syed Imran ◽  
Mal Rajaraman ◽  
Karen Chu ◽  
Stan VanUum ◽  
Stephanie Kaiser
Keyword(s):  
Thyroid Cancer ◽  
Differentiated Thyroid Cancer ◽  
Tertiary Care ◽  
Low Risk ◽  
Well Differentiated

scholarly journals Long-Term Outcomes and Prognoses of Elderly Patients (≥65-Years-Old) With Distant Metastases From Well-Differentiated Thyroid Cancer During Radioiodine Therapy and Follow-Up

2021 ◽  
Vol 11 ◽  
Author(s):  
Zhong-Ling Qiu ◽  
Chen-Tian Shen ◽  
Zhen-Kui Sun ◽  
Hong-Jun Song ◽  
Chuang Xi ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Prognostic Factors ◽  
Elderly Patients ◽  
Differentiated Thyroid Cancer ◽  
Distant Metastases ◽  
Extrathyroidal Extension ◽  
Long Term Outcomes ◽  
Well Differentiated

ObjectiveThe objective of this study was to investigate the clinicopathological characteristics, long-term outcomes, and prognostic factors of elderly patients with distant metastases at initial diagnosis from well-differentiated thyroid cancer (WDTC) during radioactive iodine (131I) treatment and follow-up.MethodsA retrospective review of medical records identified 183 elderly patients with DTC who underwent 131I treatment at our institution between 2006 and 2019.ResultsIn total, 57 elderly WDTC patients with distant metastases were enrolled in this study. After 131I treatment, 32 (56.14%) patients had 131I avidity and 25 (43.86%) had non-131I avidity; 35 (61.40%) cases were classified as radioiodine refractory (RR)-WDTC and 22 (38.60%) as non-RR-WDTC. At the end of follow-up, 25 (43.86%) patients had died and 32 (56.14%) were alive. The 5- and 10-year overall survival (OS) rates were 71.50% and 30.49%, respectively, while the 5- and 10-year disease-specific survival (DSS) rates were 76.89% and 48.71%, respectively. Multivariate analyses showed that gross extrathyroidal extension and RR-DTC were independent prognostic factors for poor OS (P=0.04 and P=0.03, respectively), while gross extrathyroidal extension, extrapulmonary distant metastases, and RR-WDTC were independent prognostic factors for poor DSS at the end of follow-up (P=0.02, P=0.03, and P=0.02, respectively).ConclusionsWDTC with distant metastases at initial diagnosis accounted for 31.15% of all elderly patients with DTC. Gross extrathyroidal extension and RR-DTC were the major factors associated with poor OS; gross extrathyroidal extension, extrapulmonary distant metastases, and RR-DTC were independent prognostic factors for poor DSS in elderly DTC patients with distant metastases.

scholarly journals Evaluation of Quality of Life Related to I-131 Therapy in Patients with Well-Differentiated Thyroid Cancer and Emphasis in Salivary Morbidity: A Follow up Study after Treatment

2014 ◽  
Vol 05 (05) ◽  
pp. 409-417 ◽  
Author(s):  
Lucélia Garcia Corrêa ◽  
Sônia Marta Moriguchi ◽  
Érica Boldrini ◽  
André Lopes de Carvalho ◽  
José Humberto Tavares Guerreiro Fregnani ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Thyroid Cancer ◽  
Differentiated Thyroid Cancer ◽  
Follow Up Study ◽  
Well Differentiated
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