Mechanisms of Estrogenic Effects on Neurobiological Functions

2004 ◽  
pp. 79-88
Author(s):  
D. W. Pfaff
Keyword(s):  
Estrogenic Effects

Estrogenic effects of pomegranate extracts in ovariectomized rats

Planta Medica ◽  
2008 ◽  
Vol 74 (09) ◽  
Author(s):  
W Promprom ◽  
W Lijuan ◽  
P Munglue ◽  
P Kupittayanant ◽  
K Indrapichate ◽  
...  
Keyword(s):  
Ovariectomized Rats ◽  
Estrogenic Effects

scholarly journals Danshen enhanced the estrogenic effects of Qing E formula in ovariectomized rats

2016 ◽  
Vol 16 (1) ◽  
Author(s):  
Jian-mei Zhang ◽  
Jin Li ◽  
Er-wei Liu ◽  
Hong Wang ◽  
Guan-wei Fan ◽  
...  
Keyword(s):  
Ovariectomized Rats ◽  
Estrogenic Effects

In vitro toxicological assessment of flumethrin’s effects on MCF-7 breast cancer cells

2021 ◽  
pp. 096032712110227
Author(s):  
S Kara-Ertekin ◽  
S Yazar ◽  
M Erkan
Keyword(s):  
Breast Cancer ◽  
Cancer Cell Line ◽  
Tail Length ◽  
Tail Moment ◽  
High Concentration ◽  
Toxicological Assessment ◽  
Estrogenic Effects ◽  
Pyrethroid Pesticides ◽  
Mcf 7

Pyrethroid pesticides are frequently used for household insect control of insects and in agriculture and livestock. Flumethrin is a pyrethroid that is used against ectoparasites in many animals. The goal of this study was to evaluate the cytotoxic, apoptotic, genotoxic, and estrogenic effects of flumethrin on the mammalian breast cancer cell line (MCF-7). Compared with control groups, a dose-dependent decrease was observed in cell viability at concentrations of 100 µM and higher. The cytotoxic and apoptotic effects detected by LDH assay and AO/EtBr staining increased significantly at a concentration of 1000 µM. The expression of BCL2, which is an anti-apoptotic gene, significantly decreased, whereas BAX, TP53, and P21 expression significantly increased. The results of a comet assay indicated that flumethrin significantly changed tail length, tail % DNA, tail moment, and Olive tail moment in concentrations above 1 and 10 µM. In addition, a 0.1 µM concentration of flumethrin affected ERα receptor mediated cell proliferation and increased transcription of estrogen-responsive pS2 (TFF1) and progesterone receptor (PGR) genes. As a result, flumethrin-induced apoptosis and cytotoxicity at a high concentration, while induced genotoxicity even at lower concentrations. Flumethrin is an endocrine disrupting insecticide with estrogenic effects at very low concentrations.

Estrogenic effects of fluorinated diiodine alkanes in MCF‐7 cells, H295R cells and zebrafish embryo assays

2019 ◽  
Vol 39 (7) ◽  
pp. 945-954 ◽  
Author(s):  
Liang Lu ◽  
Jia Chang ◽  
Yunliang Qiu ◽  
Yan Chang ◽  
Jing Ma
Keyword(s):  
Zebrafish Embryo ◽  
Estrogenic Effects ◽  
H295r Cells ◽  
Mcf 7

The protective effects of selenium-enriched spirulina on the reproductive system of male zebrafish (Danio rerio) exposed to beta-cypermethrin

2018 ◽  
Vol 9 (11) ◽  
pp. 5791-5804 ◽  
Author(s):  
Yi Zhang ◽  
Yuhang Zhou ◽  
Qingyang Tang ◽  
Feng Hu ◽  
Lixue Feng ◽  
...  
Keyword(s):  
Danio Rerio ◽  
Reproductive System ◽  
Protective Effects ◽  
Estrogenic Effects

Beta-cypermethrin (beta-CYP), which is widely used for the control of indoor and field pests, is a highly lipophilic insecticide with environmental estrogenic effects.

scholarly journals Pueraria mirifica Exerts Estrogenic Effects in the Mammary Gland and Uterus and Promotes Mammary Carcinogenesis in Donryu Rats

Toxins ◽  
2016 ◽  
Vol 8 (11) ◽  
pp. 275 ◽  
Author(s):  
Anna Kakehashi ◽  
Midori Yoshida ◽  
Yoshiyuki Tago ◽  
Naomi Ishii ◽  
Takahiro Okuno ◽  
...  
Keyword(s):  
Mammary Gland ◽  
Mammary Carcinogenesis ◽  
Pueraria Mirifica ◽  
Estrogenic Effects ◽  
Donryu Rats

scholarly journals Selective Estrogenic Effects of a Novel Triphenylethylene Compound, FC1271a, on Bone, Cholesterol Level, and Reproductive Tissues in Intact and Ovariectomized Rats1

Endocrinology ◽  
2000 ◽  
Vol 141 (2) ◽  
pp. 809-820 ◽  
Author(s):  
Qiang Qu ◽  
Huili Zheng ◽  
Johanna Dahllund ◽  
Aire Laine ◽  
Natalia Cockcroft ◽  
...  
Keyword(s):  
Cholesterol Level ◽  
Reproductive Tissues ◽  
Estrogenic Effects

Anticonceptive and estrogenic effects of a seed extract of Ricinus communis var. minor

1991 ◽  
Vol 34 (2-3) ◽  
pp. 141-145 ◽  
Author(s):  
F.K. Okwuasaba ◽  
U.A. Osunkwo ◽  
M.M. Ekwenchi ◽  
K.I. Ekpenyong ◽  
K.E. Onwukeme ◽  
...  
Keyword(s):  
Ricinus Communis ◽  
Seed Extract ◽  
Estrogenic Effects
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