Alaptide as Transdermal Permeation Modifier

2015 ◽  
pp. 115-132
Author(s):  
Josef Jampílek ◽  
Jiří Dohnal
Keyword(s):  
Transdermal Permeation

Exploring unsaturated fatty acid cholesteryl esters as transdermal permeation enhancers

2017 ◽  
Vol 7 (2) ◽  
pp. 333-345 ◽  
Author(s):  
Sanjeev Rambharose ◽  
Rahul S. Kalhapure ◽  
Mahantesh Jadhav ◽  
Thirumala Govender
Keyword(s):  
Fatty Acid ◽  
Unsaturated Fatty Acid ◽  
Cholesteryl Esters ◽  
Permeation Enhancers ◽  
Transdermal Permeation

Transdermal Permeation and Skin Retention of Diclofenac and Etofenamate/Flufenamic Acid From Over-the-Counter Pain Relief Products

2021 ◽  
Author(s):  
Monika Kopečná ◽  
Andrej Kováčik ◽  
Petr Novák ◽  
Mila Boncheva Bettex ◽  
Kateřina Vávrová
Keyword(s):  
Pain Relief ◽  
Flufenamic Acid ◽  
Over The Counter ◽  
Transdermal Permeation ◽  
Skin Retention

In vitro evaluation of transdermal permeation effects of Fu’s cupping therapy via six diffusion kinetics models

2019 ◽  
Vol 4 (1) ◽  
pp. 42–53
Author(s):  
WeiJie Xie ◽  
YuMei Wu ◽  
ShuaiShuai Chen ◽  
Jian Xu ◽  
FangFang Yang ◽  
...  
Keyword(s):  
Cupping Therapy ◽  
Diffusion Kinetics ◽  
In Vitro Evaluation ◽  
Kinetics Models ◽  
Transdermal Permeation

Influence of terminal branching on the transdermal permeation-enhancing activity in fatty alcohols and acids

2006 ◽  
Vol 14 (23) ◽  
pp. 7681-7687 ◽  
Author(s):  
Jana Klimentová ◽  
Petr Kosák ◽  
Kateřina Vávrová ◽  
Tomáš Holas ◽  
Alexandr Hrabálek
Keyword(s):  
Fatty Alcohols ◽  
Transdermal Permeation

scholarly journals FORMULATION AND EVALUATION OF IN VITRO TRANSDERMAL PATCH DICLOFENAC SODIUM USING CHITOSAN POLYMER AND POLYVINYL ALCOHOL CROSS-LINKED TRIPOLYPHOSPHATE SODIUM

2018 ◽  
Vol 11 (8) ◽  
pp. 171
Author(s):  
Julia Reveny ◽  
Sumaiyah Sumaiyah
Keyword(s):  
Moisture Absorption ◽  
Diclofenac Sodium ◽  
Chemical Characterization ◽  
Transdermal Patch ◽  
Transdermal Permeation ◽  
Physiochemical Parameters ◽  
Materials Used ◽  
Discharge Profile ◽  
Test Requirements

Objective: The aim of this study was to investigate diclofenac sodium patches using chitosan (Ch) and polyvinyl (PVA) alcohol cross-linked tripolyphosphate sodium (TPP) to increased transdermal permeation of the drug from the matrix system across rabbit skin.Materials and Methods: The chemical characterization of diclofenac sodium was done by ultraviolet-visible spectrophotometry. Formulation of diclofenac sodium patches using solvent evaporation method with cross-link technique. Evaluation of physical character of the film includes organoleptic observation, weight test, thickness, % moisture absorption, fold resistance, interaction between materials used Fourier transform infrared (FTIR), and active substance levels. The drug release was determined using Franz diffusion cells in phosphate buffer (pH 7.4).Results: The result of physiochemical parameters of the transdermal patch were found satisfactory. Formula F1, F2, F3, and F4 produce patches with fine texture, F5 and F6 formulas produce patches with coarse texture. Formula F1, F2, F5, and F6 are flexible and fulfill the multiplier test requirements, while the F3 and F4 formulas are not flexible and do not meet the multiplier test requirements. The patch weight, thickness, and drug content were uniform. The release of patches with following the zero-order release. The optimal formula with the total sodium diclofenac released as much as 17.89 μg, the release flux of 89.42 μg/cm²/h of permeation time of 10 h and the moisture absorption rate of 1.07±0.193. The FTIR data of rabbit skin indicated Ch and PVA alcohol cross-linked TPP increase transdermal permeation of diclofenac sodium in the stratum corneum.Conclusion: The diclofenac sodium can be prepared by cross-linked method, resulted in a better discharge profile.

Effect of penetration enhancers and amorphization on transdermal permeation flux of raloxifene-encapsulated solid lipid nanoparticles: an ex vivo study on human skin

2019 ◽  
Vol 9 (6) ◽  
pp. 1383-1394 ◽  
Author(s):  
Krishna Kumar Patel ◽  
Shilpkala Gade ◽  
Md. Meraj Anjum ◽  
Sanjay Kumar Singh ◽  
Pralay Maiti ◽  
...  
Keyword(s):  
Human Skin ◽  
Solid Lipid Nanoparticles ◽  
Ex Vivo ◽  
Lipid Nanoparticles ◽  
Penetration Enhancers ◽  
Permeation Flux ◽  
Transdermal Permeation ◽  
Solid Lipid ◽  
Ex Vivo Study
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