Characteristics of Cord Blood Stem Cells: Role of Substance P (SP) and Calcitonin Gene-Related Peptide (CGRP)

Author(s):  
Massoumeh Ebtekar ◽  
Somayeh Shahrokhi ◽  
Kamran Alimoghaddam
Cephalalgia ◽  
2006 ◽  
Vol 26 (11) ◽  
pp. 1287-1293 ◽  
Author(s):  
M Alessandri ◽  
L Massanti ◽  
P Geppetti ◽  
G Bellucci ◽  
M Cipriani ◽  
...  

Little is known of mechanism of dialysis headache (DH). As suggested for migraine, a role for neuropeptides has been investigated. Twenty-four patients under haemodialysis were studied. Twelve of them suffered from DH. The remaining patients were headache free. Blood samples for radioimmunoassay of calcitonin gene-related peptide (CGRP) and substance P (SP) were collected from the arteriovenous fistula before and after dialysis treatment. Basal plasma concentrations of CGRP were found to be higher in headache patients. Dialysis significantly decreased CGRP concentrations in both groups. No difference in basal plasma concentrations of SP was observed between groups. At the end of the treatment plasma SP concentrations were reduced in headache-free patients but increased in headache patients. Elevated plasma concentrations of CGRP in patients with DH could represent a biochemical factor contributing to susceptibility to headache. Because of the disputable role of SP in migraine, the significance of the increase of the peptide in plasma during DH remains to be elucidated.


2017 ◽  
Vol 5 (1) ◽  
pp. 98-101 ◽  
Author(s):  
C. Nasadyuk ◽  
A. Mahinya ◽  
S. Martynenko

The paper highlights the features of cord blood stem cells banking worldwide, modern trends of development of this biomedical industry, problems and prospects. The role of the sector of public and family cord blood banks in shaping of the market of storage of human cells and tissue is considered. The data of sociological surveys in Ukraine and abroad, to evaluate the level of awareness of future parents and medical community about the value and possibilities of storage of cord blood is presented. The study revealed favorable preconditions and emphasized the social importance of creating a public cord blood bank in Ukraine in the perspective of its integration with international registries of hematopoietic stem cells.


2013 ◽  
pp. 73-85
Author(s):  
Venkata Ramesh Dasari ◽  
Kiran Kumar Velpula ◽  
Jasti S. Rao

Hypertension ◽  
2001 ◽  
Vol 38 (3) ◽  
pp. 679-682 ◽  
Author(s):  
Khurshed A. Katki ◽  
Scott C. Supowit ◽  
Donald J. DiPette

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