Structure and Function in Nucleic Acids: Mutagenesis

1987 ◽  
pp. 92-111
Author(s):  
Ignacio Tinoco ◽  
Steven Wolk ◽  
Frances Arnold ◽  
Fareed Aboul-Ela
Keyword(s):  
Nucleic Acids ◽  
Structure And Function ◽  
And Function

III. Functions of short lifetime structures at large 9: case of nucleic acids

2018 ◽  
Vol 18 (3) ◽  
pp. 205-210
Author(s):  
Koichi Nishigaki
Keyword(s):  
Nucleic Acids ◽  
Deoxyribonucleic Acid ◽  
Structure And Function ◽  
The Poor ◽  
Methodological Difficulty ◽  
Short Lifetime ◽  
Transient Structures ◽  
And Function ◽  
Functional Rnas

Abstract The short lifetime structures of nucleic acids are not well studied because of the poor recognition of their importance and the methodological difficulty. In case of proteins, which are a type of single-stranded biopolymers, the essential roles of their transient structures are well established. Therefore, the role of transient structures of nucleic acids is, naturally, of great interest. There have been multiple reports on the function-related unstable (transient) structures of single-stranded nucleotides, though not as many as at present. Recent methodological advances are now enabling us to observe structures with ultra-short lifetime (less than a nanosecond). On the other hand, the biological importance of transient structures of ribonucleicacid (RNA) is increasingly recognized because of the findings of novel functional RNAs such as microRNA. Therefore, the time has come to tackle the structure and function dynamic of RNA/deoxyribonucleic acid in relation to their transient, unstable structures. The specific properties of rapidity and diversity are hypothesized to be involved in unexplored phenomena in neuroscience.

Cellular structure and function

2021 ◽  
pp. 1-104
Keyword(s):  
Plasma Membrane ◽  
Nucleic Acids ◽  
Cellular Structure ◽  
Structure And Function ◽  
The Body ◽  
Signalling Pathways ◽  
Cellular Functions ◽  
Pharmacological Agents ◽  
Intracellular Organelles ◽  
And Function

‘Cellular structure and function’ covers the roles, structures, and functions of the main four types of macromolecules of the human body, namely proteins, lipids, carbohydrates, and nucleic acids. For these macromolecules, the roles and types of each class are discussed (for proteins this includes their roles as structural proteins and enzymes and their kinetics; for lipids, the roles and types of lipid found in the body are considered; for carbohydrates, their roles including structural and metabolic are discussed; and the structure of nucleic acids is described). Then follows a description of the organization of the cell, including the plasma membrane and its components, and the intracellular organelles. Cell growth, division, and apoptosis are covered, as are the formation of gametes, and finally the principles of how cellular functions can be modulated by pharmacological agents through receptors and signalling pathways are discussed.

Some Effects of Metal Ions on the Structure and Function of Nucleic Acids

1973 ◽  
pp. 43-66 ◽  
Author(s):  
G. L. Eichhorn ◽  
N. A. Berger ◽  
J. J. Butzow ◽  
P. Clark ◽  
J. Heim ◽  
...  
Keyword(s):  
Nucleic Acids ◽  
Metal Ions ◽  
Structure And Function ◽  
And Function

Structure and function of nucleic acids affected by high pressure

1996 ◽  
Vol 26 (3-5) ◽  
pp. 414-415
Author(s):  
Andrzej Krzyżaniak ◽  
Piotr Sałański ◽  
Janusz Jurczak ◽  
Jan Barciszewski
Keyword(s):  
High Pressure ◽  
Nucleic Acids ◽  
Structure And Function ◽  
And Function
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