Variation in Anterior Chamber Volume During the Pilocarpine/Phenylephrine Provocative Test

Purpose. To quantify changes in anterior segment (AS) parameters after laser peripheral iridotomy (LPI) using AS-optical coherence tomography (OCT) of iris bombe. Method. AS images of eight eyes were captured before and after iris bombe and more than 2 weeks after LPI (post-LPI) using AS-OCT. We compared the following AS parameters: anterior chamber depth (ACD), anterior chamber volume (ACV), iris curvature (IC), iris thickness at 500 μm from the scleral spur (IT-1) in the middle between the iris root and pupillary margin (IT-2) and 500 μm from the pupillary margin (IT-3) to the anterior chamber angle (ACA) (angle opening distance [AOD750]), and trabecular iris space area. Results. Mean IT-1 and IT-3, but not IT-2, were lower after iris bombe (IT-1, P=0.001; IT-2, P=0.081; and IT-3, P=0.001). There were no significant differences between ACD at pre-LPI and before iris bombe (P=0.096). The mean ACV and AOD750 of iris bombe increased at post-LPI (ACV, P<0.01, and AOD750, P<0.05). The mean IT-1, IT-2, and IT-3 increased at post-LPI (all, P≤0.01). IC decreased at post-LPI (P<0.001), and ACD at post-LPI did not change. Conclusions. The iris extends and becomes thinner during iris bombe. LPI during bombe decreases the IC and increases the ACV and ACA.

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Clear-cornea cataract surgery: pupil size and shape changes, along with anterior chamber volume and depth changes. A Scheimpflug imaging study

Clinical Ophthalmology ◽

10.2147/opth.s68370 ◽

2014 ◽

pp. 2141 ◽

Cited By ~ 17

Author(s):

John Kanellopoulos ◽

George Asimellis

Keyword(s):

Cataract Surgery ◽

Anterior Chamber ◽

Pupil Size ◽

Imaging Study ◽

Size And Shape ◽

Chamber Volume ◽

Scheimpflug Imaging ◽

Anterior Chamber Volume ◽

Shape Changes

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A Simple Photogrammetric Method of Measuring Anterior Chamber Volume

American Journal of Ophthalmology ◽

10.1016/s0002-9394(14)75243-2 ◽

1978 ◽

Vol 85 (4) ◽

pp. 469-474 ◽

Cited By ~ 50

Author(s):

Susan B. Johnson ◽

Roger L. Coakes ◽

Richard F. Brubaker

Keyword(s):

Anterior Chamber ◽

Chamber Volume ◽

Anterior Chamber Volume ◽

Photogrammetric Method

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Quantitative Assessment of Anterior Chamber Volume using Slit-Lamp OCT and Pentacam

European Journal of Ophthalmology ◽

10.1177/112067210901900314 ◽

2009 ◽

Vol 19 (3) ◽

pp. 411-415 ◽

Cited By ~ 6

Author(s):

Umut Asli Dinc ◽

Banu Oncel ◽

Ebru Gorgun ◽

Levent Alimgil

Keyword(s):

Anterior Chamber ◽

Quantitative Assessment ◽

Slit Lamp ◽

Chamber Volume ◽

Anterior Chamber Volume

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Genetic Covariance Between Central Corneal Thickness and Anterior Chamber Volume: A Hungarian Twin Study

Twin Research and Human Genetics ◽

10.1017/thg.2014.54 ◽

2014 ◽

Vol 17 (5) ◽

pp. 397-404 ◽

Cited By ~ 2

Author(s):

Georgina Zsofia Toth ◽

Adel Racz ◽

Adam Domonkos Tarnoki ◽

David Laszlo Tarnoki ◽

Zita Szekelyhidi ◽

...

Keyword(s):

Anterior Chamber ◽

Central Corneal Thickness ◽

Genetic Factors ◽

Corneal Thickness ◽

Anterior Segment ◽

Angle Closure ◽

Genetic Covariance ◽

Chamber Volume ◽

Anterior Chamber Volume ◽

High Heritability

Background: Few, and inconsistent, studies have showed high heritability of some parameters of the anterior segment of the eye; however, no heritability of anterior chamber volume (ACV) has been reported, and no study has been performed to investigate the correlation between the ACV and central corneal thickness (CCT). Methods: Anterior segment measurements (Pentacam, Oculus) were obtained from 220 eyes of 110 adult Hungarian twins (41 monozygotic and 14 same-sex dizygotic pairs; 80% women; age 48.6 ± 15.5 years) obtained from the Hungarian Twin Registry. Results: Age- and sex-adjusted heritability of ACV was 85% (bootstrapped 95% confidence interval; CI: 69% to 93%), and 88% for CCT (CI: 79% to 95%). Common environmental effects had no influence, and unshared environmental factors were responsible for 12% and 15% of the variance, respectively. The correlation between ACV and CCT was negative and significant (rph = −0.35, p < .05), and genetic factors accounted for the covariance significantly (0.934; CI: 0.418, 1.061) based on the bivariate Cholesky decomposition model. Conclusion: These findings support the high heritability of ACV and central corneal thickness, and a strong genetic covariance between them, which underscores the importance of identification of the specific genetic factors and the family risk-based screening of disorders related to these variables, such as open-angle and also angle closure glaucoma and corneal endothelial alterations.

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